Zobrazeno 1 - 10
of 87
pro vyhledávání: '"Ichiro, Harada"'
Publikováno v:
STAR Protocols, Vol 3, Iss 1, Pp 101122- (2022)
Summary: Direct cardiac reprogramming, in which fibroblasts are converted into induced cardiomyocytes (iCMs) with cardiogenic transcription factors, may be a promising approach for myocardial regeneration. Here, we present a protocol for cardiac repr
Externí odkaz:
https://doaj.org/article/d0e882b0cf6a4cb5b52ff3241c04a09f
Autor:
Haruko Watanabe-Takano, Hiroki Ochi, Ayano Chiba, Ayaka Matsuo, Yugo Kanai, Shigetomo Fukuhara, Naoki Ito, Keisuke Sako, Takahiro Miyazaki, Kazuki Tainaka, Ichiro Harada, Shingo Sato, Yasuhiro Sawada, Naoto Minamino, Shu Takeda, Hiroki R. Ueda, Akihiro Yasoda, Naoki Mochizuki
Publikováno v:
Cell Reports, Vol 36, Iss 2, Pp 109380- (2021)
Summary: Mechanical stimuli including loading after birth promote bone growth. However, little is known about how mechanical force triggers biochemical signals to regulate bone growth. Here, we identified a periosteal-osteoblast-derived secretory pep
Externí odkaz:
https://doaj.org/article/f7b746b5469f41d4b717f92fbc7a86a9
Autor:
Jun-ichiro Harada, Takeshi Matsutani, Nobutoshi Hagiwara, Yoichi Kawano, Akihisa Matsuda, Nobuhiko Taniai, Tsutomu Nomura, Eiji Uchida
Publikováno v:
Case Reports in Surgery, Vol 2018 (2018)
A follow-up endoscopy in a 71-year-old Japanese man who had undergone a left lateral segmentectomy for HCC two years ago revealed an approximately 2 cm in diameter pedunculated polypoid mass in the middle part of the thoracic esophagus. Immunohistoch
Externí odkaz:
https://doaj.org/article/bb23956d98fa48cb94cd792b586c245f
Autor:
Hiro-taka Masuda, Seiichiro Ishihara, Ichiro Harada, Takeomi Mizutani, Masayori Ishikawa, Kazushige Kawabata, Hisashi Haga
Publikováno v:
BioTechniques, Vol 56, Iss 4, Pp 172-179 (2014)
We demonstrate that a (3-aminopropyl)triethoxysilane-treated glass surface is superior to an untreated glass surface for coating with extracellular matrix (ECM) proteins when used as a cell culture substrate to observe cell physiology and behavior. W
Externí odkaz:
https://doaj.org/article/182b71a38efb4d96ac3e95b8debfcdf2
Autor:
Kyoko Takata, Mito Kuroda, Teruo Kawada, Kazumitsu Ueda, Tsuyoshi Goto, Ichiro Harada, Yasuhisa Kimura, Noriyuki Kioka
Publikováno v:
Biochemical and Biophysical Research Communications. 532:205-210
Beige/brite adipocytes, which express high levels of uncoupling protein 1 (UCP1) to generate heat using stored triglycerides, are induced under specific stimuli such as cold exposure in inguinal white adipose tissue (iWAT). Although extracellular mic
Autor:
Fumiya Tamura, Shota Kurotsu, Yuto Abe, Masaki Ieda, Keiichi Fukuda, Takeshi Suzuki, Ichiro Harada, Hiroyuki Yamakawa, Taketaro Sadahiro, Ryo Fujita, Hidenori Kojima, Yu Yamada, Yoshiko Murakata, Naoto Muraoka, Tatsuya Akiyama, Hidenori Tani, Mari Isomi
Publikováno v:
Stem Cell Reports
Summary Direct cardiac reprogramming holds great potential for regenerative medicine. However, it remains inefficient, and induced cardiomyocytes (iCMs) generated in vitro are less mature than those in vivo, suggesting that undefined extrinsic factor
Publikováno v:
Journal of Fluid Science and Technology, Vol 5, Iss 2, Pp 219-234 (2010)
A mixed-flow pump with an unshrouded impeller was computed by a one-way coupled fluid-structure simulation to evaluate a prediction accuracy of stress and analyze a flow pattern which caused the largest stress. The stress occurring around a blade roo
Externí odkaz:
https://doaj.org/article/ce9e3f6edbe6461991662642a51206b9
Autor:
Chaitanya Prashant Ursekar, Soo-Kng Teo, Hiroaki Hirata, Ichiro Harada, Keng-Hwee Chiam, Yasuhiro Sawada
Publikováno v:
PLoS ONE, Vol 9, Iss 3, p e90665 (2014)
We describe the design and validation of an equibiaxial stretching device in which cells are confined to regions of homogeneous strain. Using this device, we seek to overcome a significant limitation of existing equibiaxial stretching devices, in whi
Externí odkaz:
https://doaj.org/article/242ce6cf0e3a4d23b99a7807968f6981
Autor:
Atsushi Takashima, Keisuke Sawada, Yoshinori Ichihara, Motoshi Nagao, Karina Kouzaki, Toru Ogata, Takahiro Maekawa, Noriaki Kawanishi, Koichi Nakazato, Hideki Nakamoto, Ichiro Harada, Youngjae Ryu, Yasuhiro Sawada, Michiru Makuuchi, Shunsuke Kawamura, Daisuke Yoshino, Katsuhiko Suzuki, Naoyoshi Sakitani, Masakuni Tokunaga, Kumiko Saitou, Taku Saito
Publikováno v:
Clinical Science. 132:2147-2161
Physical inactivity gives rise to numerous diseases and organismal dysfunctions, particularly those related to aging. Musculoskeletal disorders including muscle atrophy, which can result from a sedentary lifestyle, aggravate locomotive malfunction an
Autor:
Yugo Kanai, Keisuke Sako, Shu Takeda, Kazuki Tainaka, Naoki Mochizuki, Shingo Sato, Haruko Watanabe-Takano, Shigetomo Fukuhara, Naoki Ito, Hiroki Ochi, Ayaka Matsuo, Naoto Minamino, Takahiro Miyazaki, Yasuhiro Sawada, Ichiro Harada, Akihiro Yasoda, Hiroki R. Ueda, Ayano Chiba
Publikováno v:
Cell Reports, Vol 36, Iss 2, Pp 109380-(2021)
Summary: Mechanical stimuli including loading after birth promote bone growth. However, little is known about how mechanical force triggers biochemical signals to regulate bone growth. Here, we identified a periosteal-osteoblast-derived secretory pep