Zobrazeno 1 - 10
of 353
pro vyhledávání: '"Ichio Aoki"'
Autor:
Shan Gao, Yutaka Miura, Akira Sumiyoshi, Satoshi Ohno, Keisuke Ogata, Takahiro Nomoto, Makoto Matsui, Yuto Honda, Minoru Suzuki, Megumi Iiyama, Kensuke Osada, Ichio Aoki, Nobuhiro Nishiyama
Publikováno v:
Advanced Science, Vol 11, Iss 7, Pp n/a-n/a (2024)
Abstract Nano‐sized contrast agents (NCAs) hold potential for highly specific tumor contrast enhancement during magnetic resonance imaging. Given the quantity of contrast agents loaded into a single nano‐carrier and the anticipated relaxation eff
Externí odkaz:
https://doaj.org/article/b049c92763fc4672b82bdd990b49ad3d
Autor:
Shang-Wei Li, Ming-Feng Hsieh, Taehun Hong, Pengwen Chen, Kensuke Osada, Xueying Liu, Ichio Aoki, Jiashing Yu, Kevin C.-W. Wu, Horacio Cabral
Publikováno v:
Advanced NanoBiomed Research, Vol 4, Iss 1, Pp n/a-n/a (2024)
Metal–organic frameworks (MOFs), such as the magnetic resonance imaging‐fit MIL‐100 based on Fe, are gaining significant attention as versatile theranostics with high‐loading capability. Moreover, as MOFs can be engineered to target tumors, t
Externí odkaz:
https://doaj.org/article/7533571db0c547cba951b7fae784b6a5
Autor:
Akira Sumiyoshi, Sayaka Shibata, Dessislava Lazarova, Zhivko Zhelev, Ichio Aoki, Rumiana Bakalova
Publikováno v:
Redox Report, Vol 28, Iss 1 (2023)
ABSTRACTObjectives: The present study describes a pharmacological strategy for the treatment of glioblastoma by redoxcycling ‘mitocans’ such as quinone/ascorbate combination drugs, based on their tumor-selective redox-modulating effects and toler
Externí odkaz:
https://doaj.org/article/4870639b8f2a41248188487048bdc3b6
Autor:
Megumi Ueno, Raj Kumar Parajuli, Hiromu Ito, Megumi Iiyama, Saaya Suzuki, Ken-ichiro Matsumoto, Ikuo Nakanishi, Ichio Aoki, Akira Sumiyoshi
Publikováno v:
Advances in Redox Research, Vol 8, Iss , Pp 100067- (2023)
The effects of X-ray irradiation on the redox status of colorectal tissues were investigated using magnetic resonance redox imaging.The pyrrolidine-ring nitroxyl contrast agent, 3-carbamoyl-2,2,5,5-tetramethylpyrrolidine-N-oxyl (CmP), was used as a s
Externí odkaz:
https://doaj.org/article/c91f96c187594713827e5ae9e7fcb325
Autor:
Milka Mileva, Lyudmila Dimitrova, Milena Popova, Vassya Bankova, Dimo Krastev, Hristo Najdenski, Zhivko Zhelev, Ichio Aoki, Rumiana Bakalova-Zheleva
Publikováno v:
International Journal Bioautomation, Vol 25, Iss 4, Pp 315-330 (2021)
Burkitt's lymphoma is a highly aggressive type of non-Hodgkin's lymphoma, linked to the Epstein-Barr virus, which induces oxidative stress and DNA damage in the infected cells. We investigated the cytotoxicity and redox-modulating ability of ethyl ac
Externí odkaz:
https://doaj.org/article/8484255641db455080ff17e3a3b25f3e
Autor:
Kyohei Okubo, Ryuta Takeda, Shuhei Murayama, Masakazu Umezawa, Masao Kamimura, Kensuke Osada, Ichio Aoki, Kohei Soga
Publikováno v:
Science and Technology of Advanced Materials, Vol 22, Iss 1, Pp 160-172 (2021)
Rare-earth-doped nanoparticles (NPs), such as NaGdF4 nanocrystals doped with light-emitting rare earth ions, are promising bimodal probes that allow the integration of over 1000 nm near-infrared (OTN-NIR; NIR-II/III) fluorescence imaging and magnetic
Externí odkaz:
https://doaj.org/article/39f80b28c5534d55a91e40df25b46bf6
Publikováno v:
Redox Biology, Vol 55, Iss , Pp 102397- (2022)
Externí odkaz:
https://doaj.org/article/1f036ad967244d10b78c53f19daebc58
Publikováno v:
Redox Biology, Vol 53, Iss , Pp 102337- (2022)
Recent studies demonstrate that redox imbalance of NAD+/NADH and NADP+/NADPH pairs due to impaired respiration may trigger two “hidden” metabolic pathways on the crossroad between mitochondrial dysfunction, senescence, and proliferation: “β-ox
Externí odkaz:
https://doaj.org/article/b405a8941af6486cb7b90c823edb2f59
Autor:
Rumiana Bakalova, Dessislava Lazarova, Akira Sumiyoshi, Sayaka Shibata, Zhivko Zhelev, Biliana Nikolova, Severina Semkova, Tatyana Vlaykova, Ichio Aoki, Tatsuya Higashi
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 9, p 8435 (2023)
Our study proposes a pharmacological strategy to target cancerous mitochondria via redox-cycling “mitocans” such as quinone/ascorbate (Q/A) redox-pairs, which makes cancer cells fragile and sensitive without adverse effects on normal cells and ti
Externí odkaz:
https://doaj.org/article/3e9d8696110a45c9bdab1ccb30c31713
Publikováno v:
Nano Select, Vol 2, Iss 4, Pp 779-790 (2021)
Abstract Targeted theranostics can improve benefits of therapeutics or imaging probes by minimizing the dose and by selective delivery to a target site. For this study, a gold nanorod (AuNR)‐based nanohybrid was designed for efficient cancer treatm
Externí odkaz:
https://doaj.org/article/b5de1a1434d04e9cb21fbeb2d0b540e7