Zobrazeno 1 - 10
of 379
pro vyhledávání: '"Ichinosuke Hyodo"'
Autor:
Takeshi Kajiwara, Tomohiro Nishina, Riu Yamashita, Yoshiaki Nakamura, Manabu Shiozawa, Satoshi Yuki, Hiroya Taniguchi, Hiroki Hara, Takashi Ohta, Taito Esaki, Eiji Shinozaki, Atsuo Takashima, Yoshiyuki Yamamoto, Kentaro Yamazaki, Takayuki Yoshino, Ichinosuke Hyodo
Publikováno v:
Cancers, Vol 15, Iss 21, p 5172 (2023)
The treatment strategies and prognoses of patients with metastatic colorectal cancer (CRC) differ according to the sidedness of the primary tumor. TP53 gain-of-function (GOF) and non-GOF variants have been reported to be differentially associated wit
Externí odkaz:
https://doaj.org/article/c7cdc4b2ea6d48e9a0cc6563676ac09e
Autor:
Sotaro Sadahiro, Kazuhiro Sakamoto, Takashi Tsuchiya, Takao Takahashi, Hiroki Ohge, Toshihiko Sato, Ken Kondo, Yutaka Ogata, Hideo Baba, Michio Itabashi, Masataka Ikeda, Madoka Hamada, Kiyoshi Maeda, Hiroyuki Masuko, Keiichi Takahashi, Junichi Sakamoto, Mitsuo Kusano, Ichinosuke Hyodo, Masataka Taguri, Satoshi Morita
Publikováno v:
BMC Cancer, Vol 22, Iss 1, Pp 1-10 (2022)
Abstract Background The efficacy of adjuvant chemotherapy for high-risk stage II colon cancer (CC) has not been well established. We compared the effects of surgery with and without oral uracil and tegafur plus leucovorin (UFT/LV) in patients with hi
Externí odkaz:
https://doaj.org/article/451f7132142d4feca58058cfba356fff
Autor:
Hiroyuki Arai, Eisuke Inoue, Kensei Yamaguchi, Narikazu Boku, Hiroki Hara, Tomohiro Nishina, Masahiro Tsuda, Kohei Shitara, Katsunori Shinozaki, Shinichiro Nakamura, Ichinosuke Hyodo, Kei Muro, Mitsuru Sasako, Masanori Terashima, Takako E. Nakajima
Publikováno v:
Cancer Medicine, Vol 10, Iss 21, Pp 7673-7682 (2021)
Abstract Background In the JCOG1108/WJOG7312G trial, a combination (FLTAX) of 5‐fluorouracil (FU) /leucovorin (FL) and paclitaxel (PTX) did not show superiority in overall survival (OS) to FL in untreated patients with severe peritoneal metastasis
Externí odkaz:
https://doaj.org/article/5a49fbf951434c0199f4f695f82816eb
Autor:
Kohei Shitara, Taroh Satoh, Satoru Iwasa, Kensei Yamaguchi, Kei Muro, Yoshito Komatsu, Tomohiro Nishina, Taito Esaki, Jun Hasegawa, Yasuyuki Kakurai, Emi Kamiyama, Tomoko Nakata, Kota Nakamura, Hayato Sakaki, Ichinosuke Hyodo
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 7, Iss 1, Pp 1-12 (2019)
Abstract Background Erythropoietin-producing hepatocellular receptor A2 (EPHA2) is overexpressed on the cell surface in many cancers and predicts poor prognosis. DS-8895a is a humanized anti-EPHA2 IgG1 monoclonal antibody afucosylated to enhance anti
Externí odkaz:
https://doaj.org/article/e6e7417efabc4c09a8c6af99cb58e3cb
Autor:
Takao Takahashi, Kazuyuki Ishida, Yasunori Emi, Michiie Sakamoto, Johji Imura, Shinichi Aishima, Kei Muro, Hiroyuki Uetake, Eiji Oki, Yu Katayose, Kazuhiro Yoshida, Michiaki Unno, Ichinosuke Hyodo, Naohiro Tomita, Kenichi Sugihara, Yoshihiko Maehara
Publikováno v:
Cancers, Vol 14, Iss 18, p 4392 (2022)
We compared the preplanned histopathological responses of resected liver metastases from patients who received modified FOLFOX6 plus bevacizumab or modified FOLFOX6 plus cetuximab for liver-limited colorectal metastases in the ATOM trial. Fibrosis an
Externí odkaz:
https://doaj.org/article/0b0344cf4e1e4484a59255beabf340b1
Autor:
Masamichi Yamaura, Takeshi Yamada, Rei Watanabe, Hitomi Kawai, Suguru Hirose, Hiroki Tajima, Masashi Sato, Yuichi Uchida, Daisuke Suganuma, Yoshiyuki Yamamoto, Toshikazu Moriwaki, Ichinosuke Hyodo
Publikováno v:
BMC Cancer, Vol 18, Iss 1, Pp 1-6 (2018)
Abstract Background Anal canal cancer occasionally accompanies extramammary Paget disease. Although most of them are squamous cell carcinoma, anal canal adenocarcinoma with neuroendocrine features accompanying secondary extramammary Paget disease has
Externí odkaz:
https://doaj.org/article/fb297464af2e4233b2dc5cdc6e2fcd25
Autor:
Daisuke Akutsu, Hideo Suzuki, Toshiaki Narasaka, Masahiko Terasaki, Tsuyoshi Kaneko, Hirofumi Matsui, Yuji Mizokami, Ichinosuke Hyodo
Publikováno v:
Endoscopy International Open, Vol 05, Iss 01, Pp E30-E34 (2017)
Background and study aims Esophageal endoscopic submucosal dissection (ESD) is technically difficult because of narrow working spaces and ease of perforation due to the lack of serosa. HybridKnife is a recently developed ESD device that is combined w
Externí odkaz:
https://doaj.org/article/688e4cdf9c6c4937b5166db74e468577
Autor:
Sachiko Hirai, Shinji Endo, Rie Saito, Mitsuaki Hirose, Takunori Ueno, Hideo Suzuki, Kenji Yamato, Masato Abei, Ichinosuke Hyodo
Publikováno v:
PLoS ONE, Vol 9, Iss 7, p e102831 (2014)
Up-regulated sirtuin 1 (SIRT1), an NAD+-dependent class III histone deacetylase, deacetylates p53 and inhibits its transcriptional activity, leading to cell survival. SIRT1 overexpression has been reported to predict poor survival in some malignancie
Externí odkaz:
https://doaj.org/article/05397061318642f19ae9674c378b852a
Autor:
Mika, Okazawa-Sakai, Yasuko, Yamamoto, Mashu, Futagawa, Miki, Okamura, Satoko, Miyawaki, Tomohiro, Nishina, Kazuhiro, Takehara, Toshiyuki, Kozuki, Shuta, Tomida, Ichinosuke, Hyodo, Shozo, Ohsumi, Akira, Hirasawa
Publikováno v:
Acta Medica Okayama. 76(6):673-678
Patients found to have presumed germline pathogenic variants (PGPVs) during comprehensive genomic profiling (CGP) require genetic counseling (GC) referrals. We retrospectively investigated the outcomes of patients with PGPVs. Among 159 patients who u
Autor:
Yusuke Seyama, Kazuhiro Sudo, Suguru Hirose, Yukako Hamano, Takeshi Yamada, Takashi Hiroyama, Ryosuke Sasaki, Masami Yokota Hirai, Ichinosuke Hyodo, Kiichiro Tsuchiya, Yukio Nakamura
The identification and development of therapeutic targets in cancer stem cells that lead to tumor development, recurrence, metastasis, and drug resistance is an important goal in cancer research. The hepatocellular carcinoma cell line Li-7 contains f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5827698f0351971eb54c310642b49e87
https://doi.org/10.21203/rs.3.rs-2940353/v1
https://doi.org/10.21203/rs.3.rs-2940353/v1