TALK-1-mediated alterations of β-cell mitochondrial function and insulin secretion impair glucose homeostasis on a diabetogenic diet.

Autor: Graff SM; Department of Molecular Physiology and Biophysics, Vanderbilt University, Nashville, TN 37232, USA; Department of Pharmacy and Pharmaceutical Sciences, Lipscomb University, Nashville, TN 37204, USA., Nakhe AY; Department of Molecular Physiology and Biophysics, Vanderbilt University, Nashville, TN 37232, USA., Dadi PK; Department of Molecular Physiology and Biophysics, Vanderbilt University, Nashville, TN 37232, USA., Dickerson MT; Department of Molecular Physiology and Biophysics, Vanderbilt University, Nashville, TN 37232, USA., Dobson JR; Department of Molecular Physiology and Biophysics, Vanderbilt University, Nashville, TN 37232, USA., Zaborska KE; Department of Molecular Physiology and Biophysics, Vanderbilt University, Nashville, TN 37232, USA., Ibsen CE; Department of Molecular Physiology and Biophysics, Vanderbilt University, Nashville, TN 37232, USA., Butterworth RB; Department of Molecular Physiology and Biophysics, Vanderbilt University, Nashville, TN 37232, USA., Vierra NC; Department of Molecular Physiology and Biophysics, Vanderbilt University, Nashville, TN 37232, USA., Jacobson DA; Department of Molecular Physiology and Biophysics, Vanderbilt University, Nashville, TN 37232, USA. Electronic address: david.a.jacobson@vanderbilt.edu.

Publikováno v: Cell reports [Cell Rep] 2024 Jan 23; Vol. 43 (1), pp. 113673. Date of Electronic Publication: 2024 Jan 10.