Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Ibrahim T. Mughrabi"'
Autor:
Ibrahim T. Mughrabi, Michael Gerber, Naveen Jayaprakash, Santhoshi P. Palandira, Yousef Al-Abed, Timir Datta-Chaudhuri, Corey Smith, Valentin A. Pavlov, Stavros Zanos
Publikováno v:
Journal of Neuroinflammation, Vol 20, Iss 1, Pp 1-15 (2023)
Abstract Background The noradrenergic innervation of the spleen is implicated in the autonomic control of inflammation and has been the target of neurostimulation therapies for inflammatory diseases. However, there is no real-time marker of its succe
Externí odkaz:
https://doaj.org/article/89e0b92ee1164d0a8b1115da6bbd4daa
Autor:
Ibrahim T. Mughrabi, Mahendar Ochani, Mirza Tanovic, Ping Wang, Betty Diamond, Barbara Sherry, Valentin A. Pavlov, Seza Ozen, Daniel L. Kastner, Jae Jin Chae, Yousef Al-Abed
Publikováno v:
Molecular Medicine, Vol 28, Iss 1, Pp 1-11 (2022)
Abstract Background Autoinflammatory diseases, a diverse group of inherited conditions characterized by excessive innate immune activation, have limited therapeutic options. Neuroimmune circuits of the inflammatory reflex control innate immune overac
Externí odkaz:
https://doaj.org/article/31c2573a5b13408bb668d631563ddf84
Autor:
Ahmad Altiti, Mingzhu He, Sonya VanPatten, Kai Fan Cheng, Umair Ahmed, Pui Yan Chiu, Ibrahim T. Mughrabi, Bayan Al Jabari, Ronald M. Burch, Kirk R. Manogue, Kevin J. Tracey, Betty Diamond, Christine N. Metz, Huan Yang, LaQueta K. Hudson, Stavros Zanos, Myoungsun Son, Barbara Sherry, Thomas R. Coleman, Yousef Al-Abed
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-13 (2022)
The rapid protease degradation of peptides is currently limiting their therapeutic utility. Here, the authors report functionalised thiocarbazate scaffolds as precursors of aza-amino acids that can be integrated in peptide sequences, extending their
Externí odkaz:
https://doaj.org/article/a48c24524daa4e5cb8838c0018607cb6
Autor:
Ibrahim T Mughrabi, Jordan Hickman, Naveen Jayaprakash, Dane Thompson, Umair Ahmed, Eleni S Papadoyannis, Yao-Chuan Chang, Adam Abbas, Timir Datta-Chaudhuri, Eric H Chang, Theodoros P Zanos, Sunhee C Lee, Robert C Froemke, Kevin J Tracey, Cristin Welle, Yousef Al-Abed, Stavros Zanos
Publikováno v:
eLife, Vol 10 (2021)
Vagus nerve stimulation (VNS) suppresses inflammation and autoimmune diseases in preclinical and clinical studies. The underlying molecular, neurological, and anatomical mechanisms have been well characterized using acute electrophysiological stimula
Externí odkaz:
https://doaj.org/article/00fccd68672b49909ac33099dcf37e3b
Autor:
Stefanos Zafeiropoulos, Umair Ahmed, Ibrahim T Mughrabi, Naveen Jayaprakash, Chrystal Chadwick, Anna Daytz, Alexandra Bekiaridou, Nafiseh Saleknezhad, Yemil Atish-Fregoso, Kaitlin Carroll, George Giannakoulas, Yousef Al-Abed, Christopher Puleo, Mark Nicolls, Betty Diamond, Stavros Zanos
RationaleChronic inflammation is pathogenically implicated in pulmonary arterial hypertension (PAH), however, it has not been adequately targeted therapeutically.ObjectivesWe investigated whether neuromodulation of an anti-inflammatory neuroimmune pa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c0940cbac28ceb3ca7af5ee5ef36ef49
https://doi.org/10.1101/2023.03.28.534567
https://doi.org/10.1101/2023.03.28.534567
Autor:
Ibrahim T. Mughrabi, Michael Gerber, Naveen Jayaprakash, Santhoshi P. Palandira, Yousef Al-Abed, Timir Datta-Chaudhuri, Corey Smith, Valentin A. Pavlov, Stavros Zanos
BackgroundThe noradrenergic innervation of the spleen is implicated in the autonomic control of inflammation and has been the target of neurostimulation therapies for inflammatory diseases. However, there is no real-time marker of its successful acti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7bf2a84daef79c8b4f3a54b20fbfbe22
https://doi.org/10.1101/2022.04.26.489592
https://doi.org/10.1101/2022.04.26.489592
Autor:
Ibrahim T. Mughrabi, Stavros Zanos, Loren Rieth, Anna Daytz, Lance B Becker, Timir Datta-Chaudhuri, Yousef Al-Abed, Arielle H. Gabalski, Marina Cracchiolo, Theodoros P. Zanos, Yao-Chuan Chang, Umair Ahmed
Publikováno v:
Brain Stimulation, Vol 13, Iss 6, Pp 1617-1630 (2020)
Background Cervical vagus nerve stimulation (VNS) is a rapidly emerging bioelectronic treatment for brain, metabolic, cardiovascular and immune disorders. Its desired and off-target effects are mediated by different nerve fiber populations and knowle
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::10fa001dbe44c6fbe06dc4d22003b96c
https://doi.org/10.1016/j.brs.2020.09.002
https://doi.org/10.1016/j.brs.2020.09.002
Autor:
Naveen Jayaprakash, Al Abed Y, Timir Datta-Chaudhuri, Theodoros P. Zanos, Stavros Zanos, Ibrahim T. Mughrabi, Jason Wong, Jason Wright, Mathew J
Novel research in the field of bioelectronic medicine requires systems that pair high-performance neurostimulation and bio-signal acquisition hardware with advanced software signal processing and control algorithms. Although mice are the most commonl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e13388d2106f2a7e3c0597e507c01ec4
https://doi.org/10.1101/2021.06.02.446797
https://doi.org/10.1101/2021.06.02.446797
Publikováno v:
NER
Large, myelinated, motor A-fibers in the vagus innervate muscles of the larynx. They are implicated in side effects of cervical vagus nerve stimulation (VNS), laryngeal paralysis after surgical injury of the vagus, and in motor manifestations of prog
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::438ac8c86a3082f1e613e2b679111436
https://doi.org/10.1109/ner49283.2021.9441454
https://doi.org/10.1109/ner49283.2021.9441454
Autor:
Yousef Al-Abed, Kevin J. Tracey, Timir Datta-Chaudhuri, Yao-Chuan Chang, Ibrahim T. Mughrabi, Eric H. Chang, Adam Abbas, Theodoros P. Zanos, Stavros Zanos, Dane Thompson, Naveen Jayaprakash, Cristin G. Welle, Sunhee C Lee, Jordan Hickman, Umair Ahmed, Robert C. Froemke, Eleni S. Papadoyannis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::088f38f3e1ad22ca15ffe71c38624708
https://doi.org/10.7554/elife.61270.sa2
https://doi.org/10.7554/elife.61270.sa2