Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Ibrahim Olajide Gbadebo"'
Autor:
Abdul-Quddus Kehinde Oyedele, Nurudeen Abiodun Owolabi, Tope Tunji Odunitan, Abosede Ajibare Christiana, Rukayat Olajumoke Jimoh, Waliu Olatunji Abdul Azeez, Maryam Bello-Hassan Titilayo, Abiola Sarah Soares, Adedayo Toluwani Adekola, Teslim Oluwaseyi Abdulkareem, Samson Olabode Oyelekan, Mojeed Ayoola Ashiru, Ibrahim Olajide Gbadebo, Habeebah Eyinade Olajumoke, Ibrahim Damilare Boyenle, Abdeen Tunde Ogunlana
Publikováno v:
Informatics in Medicine Unlocked, Vol 37, Iss , Pp 101170- (2023)
A prospective target for the therapy of solid tumors is KRAS G12D, the most prevalent oncogenic KRAS mutation. However, despite decades of research that focused on the identification of druggable compounds against this highly challenging therapeutic
Externí odkaz:
https://doaj.org/article/5d49b7965d9e448483893b2f7c5a0d6b
Autor:
Ibrahim Olaide Adedotun, Misbaudeen Abdul-Hammed, Basirat Temidayo Egunjobi, Ubeydat Temitope Ismail, Jemilat Yetunde Yusuf, Tolulope Irapada Afolabi, Ibrahim Olajide Gbadebo
Publikováno v:
Physical Sciences Reviews.
Ovarian cancer is a crucial gynaecological unmet medical disease with a high mortality rate. According to recent research, the phosphoinositol 3 kinase (PI3K)/protein kinase B (AKT)/mammalian target of rapamycin (mTOR) pathways are hyper-activated in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c9ba04c39db0129faf7d30633d21fc3d
https://doi.org/10.1515/psr-2022-0341
https://doi.org/10.1515/psr-2022-0341
Autor:
Abdul-Quddus Kehinde Oyedele, Abdeen Tunde Ogunlana, Ibrahim Damilare Boyenle, Najahtulahi Opeyemi Ibrahim, Ibrahim Olajide Gbadebo, Nurudeen Abiodun Owolabi, Ashiru Mojeed Ayoola, Ann Christopher Francis, Olajumoke Habeebah Eyinade, Temitope Isaac Adelusi
Publikováno v:
Molecular diversity.
For decades, KRAS G12C was considered an undruggable target. However, in recent times, a covalent inhibitor known as sotorasib was discovered and approved for the treatment of patients with KRAS G12C-driven cancers. Ever since the discovery of this d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1a7ba00fbb042739d47f6de324cd821d
https://pubmed.ncbi.nlm.nih.gov/36271195
https://pubmed.ncbi.nlm.nih.gov/36271195
Autor:
Ponnadurai Ramasami, Christianah Otoame Irabor, Ibrahim Olajide Gbadebo, Monsurat Olajide, Ibrahim Olaide Adedotun, Lydia Rhyman, Tolulope Irapada Afolabi, Misbaudeen Abdul-Hammed
Publikováno v:
Natural Product Research
article-version (VoR) Version of Record
article-version (VoR) Version of Record
The current research used a virtual screening method to study 57 isolated phytochemicals (alkaloids, phytosterols, and flavonoids) against the SARS-CoV-2 main protease (Mpro). The absorption, distribution, metabolism, excretion, and toxicity (ADMET)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::749a8a6daff1c7a46c5f77658fa1aeab
https://pubmed.ncbi.nlm.nih.gov/34107799
https://pubmed.ncbi.nlm.nih.gov/34107799