Zobrazeno 1 - 10
of 106
pro vyhledávání: '"Ibrahim M Adham"'
Autor:
Odgerel Oidovsambuu, Gunsmaa Nyamsuren, Shuai Liu, Wolfgang Göring, Wolfgang Engel, Ibrahim M Adham
Publikováno v:
PLoS ONE, Vol 6, Iss 10, p e25908 (2011)
VSIG1, a cell adhesion protein of the immunoglobulin superfamily, is preferentially expressed in stomach, testis, and certain gastric, esophageal and ovarian cancers. Here, we describe the expression patterns of three alternatively spliced isoforms o
Externí odkaz:
https://doaj.org/article/138201e3eb0f44e4984937bbc44517dd
Autor:
Manar Elkenani, Amal Z. Barakat, Torsten Held, Daniel Marques Rodrigues, Sherok Mobarak, Surabhi Swarnka, Ibrahim M. Adham, Belal A. Mohamed
Publikováno v:
Journal of Translational Medicine, Vol 20, Iss 1, Pp 1-10 (2022)
Abstract Background Molecular chaperones assist protein folding, facilitate degradation of misfolded polypeptides, and thereby maintain protein homeostasis. Impaired chaperone activity leads to defective protein quality control that is implicated in
Externí odkaz:
https://doaj.org/article/8dc60591845c458a975ab700f5e81a40
Publikováno v:
The FEBS Journal. 288:3317-3329
Differentiation of the embryonic stem cells (ESCs) is regulated by a variety of different signaling pathways. Genetic depletion of murine Pelota gene (Pelo) leads to early embryonic lethality. Here, we aimed at determining the embryonic stage and dec
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::22c89571aa3877a169beb111297aa576
https://doi.org/10.1111/febs.15643
https://doi.org/10.1111/febs.15643
Autor:
Ibrahim M. Adham, Sebastian Diecke, Robin Hindmarsh, Wolfram-Hubertus Zimmermann, Peter Nürnberg, Ibrahim El-Battrawy, Yun Li, Gabriela Salinas, Lukas Cyganek, Christian D. Muller, Huan Lan, Mandy Kleinsorge, Gerd Hasenfuss, Malte Tiburcy, Boris Barbarics, Bernd Wollnik, Ulrich Hanses, Janine Altmüller, Lennart Roos, Thomas Paul, Christof Lenz, Gökhan Yigit
Publikováno v:
Circulation. 142(11)
Background: Noonan syndrome (NS) is a multisystemic developmental disorder characterized by common, clinically variable symptoms, such as typical facial dysmorphisms, short stature, developmental delay, intellectual disability as well as cardiac hype
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2caf8784e2e016ec90a139efeaa0bacf
https://pubmed.ncbi.nlm.nih.gov/32623905
https://pubmed.ncbi.nlm.nih.gov/32623905
Autor:
Pei Hsuan Li, Chia-Ling Wu, Rouan Yao, Ronald E. Law, Richard Di Marchi, Sumiko Yoshida, Kenneth Walsh, Fangzhou Wu, Joel P Berger, Dongying Zhang, Sonomi Maruyama, Blake D. Jardin, Jennifer Parker Duffen, Ibrahim M. Adham
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Background The insulin/insulin‐like growth factor/relaxin family represents a group of structurally related but functionally diverse proteins. The family member relaxin‐2 has been evaluated in clinical trials for its efficacy in the treatment of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e80ab3db8f323e0efcf61141809c4bfc
https://doi.org/10.1161/jaha.117.008441
https://doi.org/10.1161/jaha.117.008441
Autor:
Ajay Kumar Mishra, Inês Sequeira, Tony Ly, Harunori Yoshikawa, Angus I. Lamond, Rachel Green, Kifayathullah Liakath-Ali, Fiona M. Watt, Angela Oliveira Pisco, Colin Chih Chien Wu, Kalle Sipilä, Eric W. Mills, Ibrahim M. Adham, Beate M. Lichtenberger
Publikováno v:
Liakath-Ali, K, Mills, E W, Sequeira, I, Lichtenberger, B M, Pisco, A O, Sipilä, K H, Mishra, A, Yoshikawa, H, Wu, C C-C, Ly, T, Lamond, A I, Adham, I M, Green, R & Watt, F M 2018, ' An evolutionarily conserved ribosome-rescue pathway maintains epidermal homeostasis ', Nature, vol. 556, pp. 376–380 . https://doi.org/10.1038/s41586-018-0032-3
Ribosome-associated mRNA quality control mechanisms ensure the fidelity of protein translation1,2. Although these mechanisms have been extensively studied in yeast, little is known about their role in mammalian tissues, despite emerging evidence that
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0cc27db998c4bff59dcf2299f067b2ba
https://hdl.handle.net/20.500.11820/1d7a5279-db8a-4439-a96d-485fd01a39b8
https://hdl.handle.net/20.500.11820/1d7a5279-db8a-4439-a96d-485fd01a39b8
Publikováno v:
Histochemistry and cell biology. 150(1)
Tight connection between sperm head and tail is crucial for the transport of the male genome and fertilization. The linkage complex, the sperm head-to-tail coupling apparatus (HTCA), originates from the centrosome and anchors to the nuclear membrane.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d342e29aa1dcabf4821d338d39964479
https://pubmed.ncbi.nlm.nih.gov/29663073
https://pubmed.ncbi.nlm.nih.gov/29663073
Autor:
Manar Elkenani, Wolfgang Engel, Erdenechimeg Tsagaan, Priyadharsini Raju, Aleksandra Kata, Ibrahim M. Adham, Gunsmaa Nyamsuren
Publikováno v:
REPRODUCTION. 149:213-221
Pelota (Pelo) is an evolutionarily conserved gene, and its deficiency inDrosophilaaffects both male and female fertility. In mice, genetic ablation ofPeloleads to embryonic lethality at the early implantation stage as a result of the impaired develop
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::843d464e3df7ab2abc82d94de19f8c32
https://doi.org/10.1530/rep-14-0391
https://doi.org/10.1530/rep-14-0391
Autor:
Belal A. Mohamed, Torsten Held, Amal Z. Barakat, Manar Elkenani, Christian Mühlfeld, Ibrahim M. Adham, Jörg Männer
Publikováno v:
American Journal of Respiratory Cell and Molecular Biology. 50:817-824
Heat shock proteins HSPA4L and HSPA4 are closely related members of the HSP110 family and act as cochaperones. We generated Hspa4l(-/-)Hspa4(-/-) mice to investigate a functional complementarity between HSPA4L and HSPA4 during embryonic development.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7d37996e8e9afc6d51e988811c0fe13b
https://doi.org/10.1165/rcmb.2013-0132oc
https://doi.org/10.1165/rcmb.2013-0132oc
Autor:
Jörg Schmidtke, Grazia Mauceri, Stephanie Schubert, Britta Marohn, Anja Schöner, Ibrahim M. Adham, Bernhard Vaske
Publikováno v:
Biology of Reproduction. 83:20-26
TSPY encodes the testis-specific protein Y-linked. In man, expression of TSPY is restricted to the testis, where TSPY is expressed in spermatogonia, primary spermatocytes, and round spermatids, and to the prostate gland. There is circumstantial evide
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2efbba5ea5586f04fab4f537cc5efd31
https://doi.org/10.1095/biolreprod.109.082156
https://doi.org/10.1095/biolreprod.109.082156