Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Ibrahim H. Polat"'
Autor:
Ibrahim H. Polat, Míriam Tarrado-Castellarnau, Adrian Benito, Claudia Hernandez-Carro, Josep Centelles, Silvia Marin, Marta Cascante
Publikováno v:
Antioxidants, Vol 10, Iss 9, p 1349 (2021)
Nucleotide pools need to be constantly replenished in cancer cells to support cell proliferation. The synthesis of nucleotides requires glutamine and 5-phosphoribosyl-1-pyrophosphate produced from ribose-5-phosphate via the oxidative branch of the pe
Externí odkaz:
https://doaj.org/article/360bf3d7c41645e5b7019a591e55cfd7
Autor:
Míriam Tarrado-Castellarnau, Santiago Diaz-Moralli, Ibrahim H. Polat, Rebeca Sanz-Pamplona, Cristina Alenda, Víctor Moreno, Antoni Castells, Marta Cascante
Publikováno v:
Translational Medicine Communications, Vol 2, Iss 1, Pp 1-9 (2017)
Abstract Background Glyceraldehyde-3-phosphate dehydrogenase (GAPDH) is an essential regulator of glycolysis used as a housekeeping marker for gene/protein normalisation. Given the pivotal role of GAPDH in tumour metabolism, our aim was to correlate
Externí odkaz:
https://doaj.org/article/99bd00c6b6c84226bcc7b8d84a205cae
Autor:
Ibrahim H. Polat, Míriam Tarrado-Castellarnau, Rohit Bharat, Jordi Perarnau, Adrian Benito, Roldán Cortés, Philippe Sabatier, Marta Cascante
Publikováno v:
Biology, Vol 10, Iss 2, p 85 (2021)
The pentose phosphate pathway (PPP) plays an essential role in the metabolism of breast cancer cells for the management of oxidative stress and the synthesis of nucleotides. 6-phosphogluconate dehydrogenase (6PGD) is one of the key enzymes of the oxi
Externí odkaz:
https://doaj.org/article/bfff6e3ccbea44878a91cece93a626dd
Autor:
Brandts, Fatima Baker, Ibrahim H. Polat, Khalil Abou-El-Ardat, Islam Alshamleh, Marlyn Thoelken, Daniel Hymon, Andrea Gubas, Sebastian E. Koschade, Jonas B. Vischedyk, Manuel Kaulich, Harald Schwalbe, Shabnam Shaid, Christian H.
Publikováno v:
Cancers; Volume 13; Issue 23; Pages: 6142
Autophagy is an important survival mechanism that allows recycling of nutrients and removal of damaged organelles and has been shown to contribute to the proliferation of acute myeloid leukemia (AML) cells. However, little is known about the mechanis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=multidiscipl::076a2c764936ef166e630216533be8b9
Autor:
Fatima Baker, Ibrahim H. Polat, Khalil Abou-El-Ardat, Islam Alshamleh, Marlyn Thoelken, Daniel Hymon, Andrea Gubas, Sebastian E. Koschade, Jonas B. Vischedyk, Manuel Kaulich, Harald Schwalbe, Shabnam Shaid, Christian H. Brandts
Publikováno v:
Cancers
Cancers, Vol 13, Iss 6142, p 6142 (2021)
Cancers, Vol 13, Iss 6142, p 6142 (2021)
Simple Summary The importance of autophagy in leukemia progression and survival has been studied previously. However, little is known about the development of resistance mechanisms to autophagy inhibition in leukemia. Here, we present data on the mec
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::8311a5854e8796698445780776050256
http://europepmc.org/articles/PMC8657081
http://europepmc.org/articles/PMC8657081
Autor:
Carles Foguet, Vitaly A. Selivanov, Rotem Katzir, Marta Cascante, Philippe Sabatier, Eytan Ruppin, Shir Katz, Ibrahim H. Polat, Michal Harel, Tamar Geiger
Publikováno v:
Scientific Reports, Vol 9, Iss 1, Pp 1-12 (2019)
Scientific Reports
Dipòsit Digital de la UB
Universidad de Barcelona
Scientific Reports
Dipòsit Digital de la UB
Universidad de Barcelona
Altered metabolism is a hallmark of cancer, but little is still known about its regulation. In this study, we measure transcriptomic, proteomic, phospho-proteomic and fluxomics data in a breast cancer cell-line (MCF7) across three different growth co
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cbf49e96d3ec0211df64fc66b8a169b7
http://link.springer.com/article/10.1038/s41598-019-54221-y
http://link.springer.com/article/10.1038/s41598-019-54221-y
Autor:
Adrian Benito, Jordi Perarnau, Marta Cascante, Ibrahim H. Polat, Philippe Sabatier, Roldán Cortés, Míriam Tarrado-Castellarnau, Rohit Bharat
Publikováno v:
Biology
Volume 10
Issue 2
Dipòsit Digital de la UB
Universidad de Barcelona
Biology, Vol 10, Iss 85, p 85 (2021)
Volume 10
Issue 2
Dipòsit Digital de la UB
Universidad de Barcelona
Biology, Vol 10, Iss 85, p 85 (2021)
Simple Summary Cancer cells alter their metabolism to maintain their high need for energy, produce enough macromolecules for biosynthesis, and preserve their redox status. The investigation of cancer cell-specific metabolic alterations has vital impo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::46e0e852bf435b14cb2aff7cdb86433d
Autor:
Míriam Tarrado-Castellarnau, Silvia Marin, Claudia Hernandez-Carro, Marta Cascante, Adrian Benito, Ibrahim H. Polat, Josep J. Centelles
Publikováno v:
Dipòsit Digital de la UB
Universidad de Barcelona
Antioxidants
Volume 10
Issue 9
Antioxidants, Vol 10, Iss 1349, p 1349 (2021)
Universidad de Barcelona
Antioxidants
Volume 10
Issue 9
Antioxidants, Vol 10, Iss 1349, p 1349 (2021)
Nucleotide pools need to be constantly replenished in cancer cells to support cell proliferation. The synthesis of nucleotides requires glutamine and 5-phosphoribosyl-1-pyrophosphate produced from ribose-5-phosphate via the oxidative branch of the pe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4802203ee8c884241f86845eb7531ea4
http://hdl.handle.net/2445/181347
http://hdl.handle.net/2445/181347
Autor:
Marta Larroya, Clara Murillo, Ibrahim H. Polat, Ana B. Sánchez-García, Teresa Cobo, José Ríos, Claudia Rueda, Silvia Marin, Eduard Gratacós, Marta Cascante
Publikováno v:
Digital.CSIC. Repositorio Institucional del CSIC
instname
instname
Although the influence of microbial invasion of the amniotic cavity on the development of spontaneous preterm delivery is unquestionable, the use of an invasive procedure to diagnose the status of an infection limits its clinical translation.
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Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2e83a6859209d8098eadfb2308dd29cb
https://pubmed.ncbi.nlm.nih.gov/32717258
https://pubmed.ncbi.nlm.nih.gov/32717258
Autor:
Adrian Benito, Ibrahim H. Polat, Marta Cascante, Silvia Marin, Carlos J. Ciudad, Véronique Noé
Publikováno v:
Oncotarget
Dipòsit Digital de la UB
Universidad de Barcelona
Dipòsit Digital de la UB
Universidad de Barcelona
The pentose phosphate pathway is a fundamental metabolic pathway that provides cells with ribose and NADPH required for anabolic reactions - synthesis of nucleotides and fatty acids - and maintenance of intracellular redox homeostasis. It plays a key
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::37b11b5bcc5da9c1e45e3ebd8182aa66
http://europepmc.org/articles/PMC5739767
http://europepmc.org/articles/PMC5739767