Zobrazeno 1 - 10
of 195
pro vyhledávání: '"Ibrahim H, Eissa"'
Autor:
Ibrahim H. Eissa, Reda G. Yousef, Eslam B. Elkaeed, Aisha A. Alsfouk, Dalal Z. Husein, Ibrahim M. Ibrahim, Ahmed Ismail, Hazem Elkady, Ahmed M. Metwaly
Publikováno v:
ACS Omega, Vol 9, Iss 14, Pp 15861-15881 (2024)
Externí odkaz:
https://doaj.org/article/b004c67ecc314a46bfafaba99f91a655
Autor:
Akram Hegazy, Raya Soltane, Ahlam Alasiri, Islam Mostafa, Ahmed M. Metwaly, Ibrahim H. Eissa, Sara H. Mahmoud, Abdou Kamal Allayeh, Noura M. Abo Shama, Ahmed A. Khalil, Ramya S. Barre, Assem Mohamed El-Shazly, Mohamed A. Ali, Luis Martinez-Sobrido, Ahmed Mostafa
Publikováno v:
BMC Complementary Medicine and Therapies, Vol 24, Iss 1, Pp 1-26 (2024)
Abstract Background The continuous evolution of drug-resistant influenza viruses highlights the necessity for repurposing naturally-derived and safe phytochemicals with anti-influenza activity as novel broad-spectrum anti-influenza medications. Metho
Externí odkaz:
https://doaj.org/article/459bd18dc3af4adf98e62c9bf91380b9
Autor:
Sanagik Sabry Abu El Wafa, Ahmed A. El-Ashmawy, Hanaa A. H. Kassem, Ibrahim H. Eissa, Mohammed Abu-Elghait, Nermin A. Younis, Inas Y. Younis
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-16 (2023)
Abstract Pelargonium graveolens L'Hér is an important species of genus Pelargonium with an economic value. The unique rose scent of its oil is used in perfume and cosmetic industry. The oil is characterized by the presence of citronellol, geraniol a
Externí odkaz:
https://doaj.org/article/46b71a92211b4643b060757401f75aa0
Autor:
Ahmed M Metwaly, Esmail M El-Fakharany, Aisha A Alsfouk, Ibrahim M Ibrahim, Eslam B Elkaeed, Ibrahim H Eissa
Publikováno v:
PLoS ONE, Vol 19, Iss 12, p e0312866 (2024)
To find an effective inhibitor for SARS-CoV-2, Quercetin's chemical structure was compared to nine ligands associated with nine key SARS-CoV-2 proteins. It was found that Quercetin closely resembles Remdesivir, the co-crystallized ligand of RNA-depen
Externí odkaz:
https://doaj.org/article/e4b0229c61114fdabb544487aaac910a
Autor:
Ibrahim H. Eissa, Abdulrahman M. Saleh, Sara T. Al-Rashood, Abdul-Aziz M. M. El-Attar, Ahmed M. Metwaly
Publikováno v:
Journal of Chemistry, Vol 2024 (2024)
As a follow-up to our teamwork’s former work against SARS-CoV-2, eight compounds (ramelteon (68), prilocaine (224), nefiracetam (339), cyclandelate (911), mepivacaine (2325), ropivacaine (2351), tasimelteon (2384), and levobupivacaine (2840)) were
Externí odkaz:
https://doaj.org/article/5bbc0fa8f04a42a4addd5572504b7209
Autor:
Ibrahim H. Eissa, Muhammad Abd ElGayed Bkrah, Reda G. Yousef, Hazem Elkady, Eslam B. Elkaeed, Bshra A. Alsfouk, Ibrahim M. Ibrahim, Ahmed M. Metwaly, Dalal Z. Husein
Publikováno v:
Journal of Chemistry, Vol 2024 (2024)
A new nicotinamide derivative, (E)-N-(4-(1-(2-(4-benzamidobenzoyl)hydrazone)ethyl)phenyl)nicotinamide, was designed as a VEGFR-2 inhibitor. Utilizing the density functional theory (DFT) calculations, the three-dimensional structure of the designed co
Externí odkaz:
https://doaj.org/article/6562b0ebed124687ba78da8bd3270b1e
Autor:
Ibrahim H. Eissa, Hazem Elkady, Mahmoud Rashed, Alaa Elwan, Mohamed Hagras, Mohammed A. Dahab, Mohammed S. Taghour, Ibrahim M. Ibrahim, Dalal Z. Husein, Eslam B. Elkaeed, Hanan A. Al-ghulikah, Ahmed M. Metwaly, Hazem A. Mahdy
Publikováno v:
Heliyon, Vol 10, Iss 2, Pp e24005- (2024)
In this study, a series of seven novel 2,4-dioxothiazolidine derivatives with potential anticancer and VEGFR-2 inhibiting abilities were designed and synthesized as VEGFR-2 inhibitors. The synthesized compounds were tested in vitro for their potentia
Externí odkaz:
https://doaj.org/article/941a6ba96f1444fc9f1952738aba1c7c
Autor:
Ahmed M. Metwaly, Moustafa M. Saleh, Bshra A. Alsfouk, Ibrahim M. Ibrahim, Muhamad Abd-Elraouf, Eslam B. Elkaeed, Ibrahim H. Eissa
Publikováno v:
Heliyon, Vol 10, Iss 2, Pp e24075- (2024)
Staphylococcus aureus is a highly prevalent and aggressive human pathogen causing a wide range of infections. This study aimed to explore the potential of Patuletin, a rare natural flavone, as an anti-virulence agent against S. aureus. At a sub-inhib
Externí odkaz:
https://doaj.org/article/ffc93f71c6464cbb90adfca63bce9e55
Autor:
Ibrahim H Eissa, Reda G Yousef, Eslam B Elkaeed, Aisha A Alsfouk, Dalal Z Husein, Ibrahim M Ibrahim, Hesham A El-Mahdy, Hazem Elkady, Ahmed M Metwaly
Publikováno v:
Evolutionary Bioinformatics, Vol 19 (2023)
The overexpression of the Epidermal Growth Factor Receptor (EGFR) marks it as a pivotal target in cancer treatment, with the aim of reducing its proliferation and inducing apoptosis. This study aimed at the CADD of a new apoptotic EGFR inhibitor. The
Externí odkaz:
https://doaj.org/article/646090e38afb4cf69efe8364aced2105
Autor:
Ibrahim H. Eissa, Reda G. Yousef, Mostafa A. Asmaey, Hazem Elkady, Dalal Z. Husein, Aisha A. Alsfouk, Ibrahim M. Ibrahim, Mohamed A. Elkady, Eslam B. Elkaeed, Ahmed M. Metwaly
Publikováno v:
Saudi Pharmaceutical Journal, Vol 31, Iss 12, Pp 101852- (2023)
VEGFR-2 is a significant target in cancer treatment, inhibiting angiogenesis and impeding tumor growth. Utilizing the essential pharmacophoric structural properties, a new semi-synthetic theobromine analogue (T-1-MBHEPA) was designed as VEGFR-2 inhib
Externí odkaz:
https://doaj.org/article/fb21ad7bdf7e4aa894fa67c446b73100