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pro vyhledávání: '"Ibogamine"'
Akademický článek
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Publikováno v:
Forensic Toxicology
Forensic Toxicology, Springer Verlag, 2020, 38 (2), pp.447-454. ⟨10.1007/s11419-020-00531-0⟩
Forensic Toxicology, 2020, 38 (2), pp.447-454. ⟨10.1007/s11419-020-00531-0⟩
Forensic Toxicology, Springer Verlag, 2020, 38 (2), pp.447-454. ⟨10.1007/s11419-020-00531-0⟩
Forensic Toxicology, 2020, 38 (2), pp.447-454. ⟨10.1007/s11419-020-00531-0⟩
International audience; Purpose Identifying xenobiotics involved in deaths remains a challenge in toxicology, especially when they are missing from the usual suspect databases. The tool development for the rapid processing of untargeted screening dat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::217cdf3ce0f93525432d3b04a48af17b
https://doi.org/10.1007/s11419-020-00531-0
https://doi.org/10.1007/s11419-020-00531-0
Autor:
Teresa de Jesús Olivera-Flores, Felix Krengel, Ricardo Reyes-Chilpa, Josefina Herrera-Santoyo
Publikováno v:
Plant Cell, Tissue and Organ Culture (PCTOC). 138:215-227
Monoterpenoid indole alkaloids (MIAs) of the ibogan type, such as ibogaine, have shown promising antiaddictive effects against several drugs of abuse in humans and animal models of addiction. Unfortunately, international ibogaine demand has led to th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::877fa10223cc0820fa9f565937067679
https://doi.org/10.1007/s11240-019-01629-z
https://doi.org/10.1007/s11240-019-01629-z
Autor:
Scott C. Farrow, Jessica Meades, Belinda Ameyaw, Mohamed O. Kamileen, Sarah E. O'Connor, Youli Xiao
Publikováno v:
The Journal of Biological Chemistry
Monoterpenoid indole alkaloids are a large (approximate to 3000 members) and structurally diverse class of metabolites restricted to a limited number of plant families in the order Gentianales. Tabernanthe iboga or iboga (Apocynaceae) is native to we
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::70a98af95692f23702a85b913ec7c85e
http://europepmc.org/articles/PMC6130943
http://europepmc.org/articles/PMC6130943
Autor:
Simon J. Kim, Robert A. Batey
Publikováno v:
Organic Chemistry Frontiers. 5:2934-2939
An enantioselective route to substituted chiral isoquinuclidines, present in alkaloids such as catharanthine, deserpidine, ibogamine and ibogaine, has been developed using a “ketene equivalent” approach. Organocatalyzed Diels–Alder reaction of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7b43ca525cd688666314fae94b29c989
https://doi.org/10.1039/c8qo00849c
https://doi.org/10.1039/c8qo00849c
Autor:
Muhammad Faisal, Shomaila Saeed, Parvez Ali Mahesar, Bhajan Lal, Danish Shahzad, Jamaluddin Mahar, Aamer Saeed, Fayaz Ali Larik, Pervaiz Ali Channar
Publikováno v:
Tetrahedron: Asymmetry. 28:1445-1461
Isoquinuclidines constitute the central structural nucleus of numerous biologically active natural products, for example, iboga alkaloids such as ibogamine and catharanthine as well as non-indole-containing alkaloids such as the dioscorine and the ca
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::231ed3e33c85c82e7ff6ef1e7a86d715
https://doi.org/10.1016/j.tetasy.2017.10.013
https://doi.org/10.1016/j.tetasy.2017.10.013
Publikováno v:
Chemistrybiodiversity. 16(7)
Several species from the Apocynaceae family, such as Tabernanthe iboga, Voacanga africana, and many Tabernaemontana species, produce ibogan type alkaloids, some of which present antiaddictive properties. In this study, we used gas chromatography/mass
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::255c02f924c56bb7b581b197a3a76b16
https://pubmed.ncbi.nlm.nih.gov/31095891
https://pubmed.ncbi.nlm.nih.gov/31095891
Autor:
Ricardo Reyes Chilpa, Quentin Chevalier, Jonathan Dickinson, Josefina Herrera Santoyo, Felix Krengel
Publikováno v:
Chemistry & Biodiversity. 16
Ibogaine and other ibogan type alkaloids present anti-addictive effects against several drugs of abuse and occur in different species of the Apocynaceae family. In this work, we used gas chromatography-mass spectrometry (GC/MS) and principal componen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b83266fe256ec24d29e360c4f4cf247f
https://doi.org/10.1002/cbdv.201800506
https://doi.org/10.1002/cbdv.201800506
Dissertation/ Thesis
DISCOVERY OF NOVEL MACROLIDE ANTIBIOTICS AND METHODOLOGY DEVELOPMENT OF N-SULFINYL METALLODIENAMINES
Autor:
Jin, Xiao
My Ph.D. research consists of two components: discovery of novel macrolide antibiotics and methodology development of N-sulfinyl metallodienamines. To tackle bacterial resistance, new antibiotics are desperately needed. My research objective is to ad
Externí odkaz:
http://hdl.handle.net/20.500.12613/615
DISCOVERY OF NOVEL MACROLIDE ANTIBIOTICS AND METHODOLOGY DEVELOPMENT OF N-SULFINYL METALLODIENAMINES
My Ph.D. research consists of two components: discovery of novel macrolide antibiotics and methodology development of N-sulfinyl metallodienamines. To tackle bacterial resistance, new antibiotics are desperately needed. My research objective is to ad
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d7de82af2dfea83a1848e5ec46518922