Molecular and phenotypic profiling of colorectal cancer patients in West Africa reveals biological insights.

Autor: Alatise OI; Faculty of Clinical Sciences, College of Health Sciences, Obafemi Awolowo University, Ile-Ife, Nigeria., Knapp GC; Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, NY, USA.; Division of General Surgery, Department of Surgery, Dalhousie University, Halifax, NS, Canada., Sharma A; Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Chatila WK; Marie-Jose and Henry R. Kravis Center for Molecular Oncology, Memorial Sloan Kettering Cancer Center, New York, NY, USA.; Human Oncology and Pathogenesis Program, Memorial Sloan Kettering Cancer Center, New York, NY, USA.; Tri-Institutional Program in Computational Biology and Medicine, Weill Cornell Medical College, New York, NY, USA., Arowolo OA; Faculty of Clinical Sciences, College of Health Sciences, Obafemi Awolowo University, Ile-Ife, Nigeria., Olasehinde O; Faculty of Clinical Sciences, College of Health Sciences, Obafemi Awolowo University, Ile-Ife, Nigeria., Famurewa OC; Faculty of Clinical Sciences, College of Health Sciences, Obafemi Awolowo University, Ile-Ife, Nigeria., Omisore AD; Faculty of Clinical Sciences, College of Health Sciences, Obafemi Awolowo University, Ile-Ife, Nigeria., Komolafe AO; Faculty of Clinical Sciences, College of Health Sciences, Obafemi Awolowo University, Ile-Ife, Nigeria., Olaofe OO; Faculty of Clinical Sciences, College of Health Sciences, Obafemi Awolowo University, Ile-Ife, Nigeria., Katung AI; Federal Medical Centre, Owo, Ondo State, Nigeria., Ibikunle DE; Federal Medical Centre, Owo, Ondo State, Nigeria., Egberongbe AA; Federal Medical Centre, Owo, Ondo State, Nigeria., Olatoke SA; Department of Surgery, University of Ilorin Teaching Hospital, Ilorin, Nigeria., Agodirin SO; Department of Surgery, University of Ilorin Teaching Hospital, Ilorin, Nigeria., Adesiyun OA; Department of Surgery, University of Ilorin Teaching Hospital, Ilorin, Nigeria., Adeyeye A; Department of Surgery, University of Ilorin Teaching Hospital, Ilorin, Nigeria., Kolawole OA; Department of Surgery, Ladoke Akintola University of Technology, Ogbomoso, Oyo State, Nigeria., Olakanmi AO; Department of Surgery, University of Medical Sciences, Ondo, Ondo State, Nigeria., Arora K; Marie-Jose and Henry R. Kravis Center for Molecular Oncology, Memorial Sloan Kettering Cancer Center, New York, NY, USA.; Human Oncology and Pathogenesis Program, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Constable J; Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Shah R; Marie-Jose and Henry R. Kravis Center for Molecular Oncology, Memorial Sloan Kettering Cancer Center, New York, NY, USA.; Human Oncology and Pathogenesis Program, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Basunia A; Marie-Jose and Henry R. Kravis Center for Molecular Oncology, Memorial Sloan Kettering Cancer Center, New York, NY, USA.; Human Oncology and Pathogenesis Program, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Sylvester B; Human Oncology and Pathogenesis Program, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Wu C; Human Oncology and Pathogenesis Program, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Weiser MR; Colorectal Service, Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Seier K; Department of Epidemiology and Biostatistics, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Gonen M; Department of Epidemiology and Biostatistics, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Stadler ZK; Clinical Genetics Service and the Cancer Biology and Genetics Program, Memorial Sloan Kettering Cancer Center, New York, NY, USA.; Gastrointestinal Oncology Service, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Kemel Y; Niehaus Center for Inherited Cancer Genomics, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Vakiani E; Human Oncology and Pathogenesis Program, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Berger MF; Human Oncology and Pathogenesis Program, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Chan TA; Human Oncology and Pathogenesis Program, Memorial Sloan Kettering Cancer Center, New York, NY, USA.; Department of Radiation Oncology, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Solit DB; Human Oncology and Pathogenesis Program, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Shia J; Department of Pathology, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Sanchez-Vega F; Human Oncology and Pathogenesis Program, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Schultz N; Human Oncology and Pathogenesis Program, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Brennan M; Bobst International Center, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Smith JJ; Human Oncology and Pathogenesis Program, Memorial Sloan Kettering Cancer Center, New York, NY, USA.; Colorectal Service, Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Kingham TP; Hepatopancreatobiliary Service, Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, NY, USA. kinghamt@mskcc.org.

Publikováno v: Nature communications [Nat Commun] 2021 Nov 24; Vol. 12 (1), pp. 6821. Date of Electronic Publication: 2021 Nov 24.