Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Ibha Rai"'
Autor:
Fang Yu, Kelsey Klute, Kamiya Mehla, Ravi Thakur, Gavin Graves, Junichi Sadoshima, Rebecca E. Oberley-Deegan, Michael A. Hollingsworth, Divya Murthy, Camila G. Pacheco, Scott E. Mulder, Nina V. Chaika, Kuldeep S. Attri, Kyla Buettner, Melissa Teoh-Fitzgerald, Pankaj K. Singh, Jaime Abrego, Ibha Rai, Paul M. Grandgenett, Aneesha Dasgupta, Bradley N. Reames, Surendra K. Shukla, David A. Tuveson, Enza Vernucci, Nicholas J Mullen, Ryan J. King, Dezhen Wang, Michael Punsoni, Matthew C. Zimmerman, Dannielle D. Engle
Publikováno v:
The Journal of experimental medicine, vol 217, iss 7
The Journal of Experimental Medicine
The Journal of Experimental Medicine
This study demonstrates a novel signaling pathway regulating pancreatic cancer cachexia. These results establish that the Sirt1–Nox4 signaling axis plays an essential role in the manifestation of pancreatic cancer cachexia, and inhibition of this a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b95eacb1b84092379889e72b0d37e57c
https://escholarship.org/uc/item/1xf460n5
https://escholarship.org/uc/item/1xf460n5
Autor:
Kamiya Mehla, Venugopal Gunda, Anusha Mishra, Ibha Rai, Ryan King, Joshua Soucheck, Gennifer D. Goode, Aneesha Dasgupta, Enza Vernucci, Surendra K. Shukla, Sangeetha Natrajan, Fang Yu, Pankaj K. Singh, Nina V. Chaika
Publikováno v:
Cancer Research. 76:10-10
Cancer cachexia is a systemic syndrome characterized by progressive weight loss of the patient due to muscle wasting and fat depletion with or without anorexia. About 80% of pancreatic ductal adenocarcinoma (PDAC) patients exhibits cachectic phenotyp