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pro vyhledávání: '"Iberiotoxin"'
Akademický článek
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Akademický článek
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Autor:
András Horváth, Torsten Christ, Jussi T. Koivumäki, Maksymilian Prondzynski, Antonia T. L. Zech, Michael Spohn, Umber Saleem, Ingra Mannhardt, Bärbel Ulmer, Evaldas Girdauskas, Christian Meyer, Arne Hansen, Thomas Eschenhagen, Marc D. Lemoine
Publikováno v:
Cells, Vol 9, Iss 1, p 253 (2020)
Human induced pluripotent stem cell-derived cardiomyocytes (hiPSC-CMs) represent an unlimited source of human CMs that could be a standard tool in drug research. However, there is concern whether hiPSC-CMs express all cardiac ion channels at physiolo
Externí odkaz:
https://doaj.org/article/3763edddbe7747caaa9a423b5f025cfe
Autor:
Eva A. Rog-Zielinska, Elisa Darkow, Susanne Proksch, Matthias Karck, Dorothee Jakob, Peter Kohl, Fabian A. Kari, Constanze Schmidt, Alexander Klesen, Ramona Emig, Tim Guth, Hélène Guizouarn, Stephan R Künzel, Diana Aria, Benoit Allegrini, Rémi Peyronnet, Ana Simon Chica, Friedhelm Beyersdorf, Stéphane N. Hatem, Ursula Ravens
Publikováno v:
Journal of Molecular and Cellular Cardiology
Journal of Molecular and Cellular Cardiology, 2021, 158, pp.49-62. ⟨10.1016/j.yjmcc.2021.05.002⟩
Journal of Molecular and Cellular Cardiology, 2021, 158, pp.49-62. ⟨10.1016/j.yjmcc.2021.05.002⟩
International audience; Aims: Atrial Fibrillation (AF) is an arrhythmia of increasing prevalence in the aging populations of developed countries. One of the important indicators of AF is sustained atrial dilatation, highlighting the importance of mec
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9728446bc28c83db545c9617ade2af8c
https://doi.org/10.1016/j.yjmcc.2021.05.002
https://doi.org/10.1016/j.yjmcc.2021.05.002
Publikováno v:
British Journal of Pharmacology. 178:4119-4136
Background and purpose KATP channels are negative regulators of lymphatic vessel excitability and contractility and are proposed to be targets for immune cell products that inhibit lymph transport. Previous studies in rat and guinea pig mesenteric ly
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6dfb88449716444c4031dae2b3974650
https://doi.org/10.1111/bph.15602
https://doi.org/10.1111/bph.15602
Autor:
Ji-Yue Wen, Zhi-Wu Chen, Ye Chen, Jing-Si Duan, Fang Zhang, Shuo Chen, Yi-Fei Fan, Zi-Yao Ma, Yang Zhang, Wei-Ming Xie, Jie Zhang
Publikováno v:
British Journal of Pharmacology. 178:4155-4175
BACKGROUND AND PURPOSE Endothelium-derived hyperpolarizing factor (EDHF) has been suggested as a therapeutic target for vascular protection against ischaemic brain injury. However, the molecular entity of EDHF and its action on neurons remains unclea
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ce622a513d8d58159c92773d120c8e62
https://doi.org/10.1111/bph.15607
https://doi.org/10.1111/bph.15607
Autor:
Hu-die Li, Chang-peng Cui, Dali Luo, Xue-lian Li, Hai-lan Ma, Meng Zhou, Zhao Qian, Lu-qi Wang, Bai-Yan Li
Publikováno v:
Acta Pharmacol Sin
Female-specific subpopulation of myelinated Ah-type baroreceptor neurons (BRNs) in nodose ganglia is the neuroanatomical base of sexual-dimorphic autonomic control of blood pressure regulation, and KCa1.1 is a key player in modulating the neuroexcita
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e2a2a4b6e848938847b1abafb8de1b66
https://doi.org/10.1038/s41401-021-00722-4
https://doi.org/10.1038/s41401-021-00722-4
Autor:
Cengiz Güven, Ali Parlar
Publikováno v:
Current Medical Science. 41:381-389
The aim of the current study was to investigate the pharmacological activity of glabridin on the isolated human saphenous vein (SV) and explore the underlying mechanisms. Samples of patients' SVs were removed during bypass surgery, and 4-mm lengths o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2832fba9d920b508d7188d17beea5af7
https://doi.org/10.1007/s11596-021-2358-6
https://doi.org/10.1007/s11596-021-2358-6
Autor:
Predrag Milojevic, Hai-Tao Hou, Dragoslav Nenezic, Guo-Wei He, Ivan Stojanovic, Aleksandra Novakovic, Qin Yang, Marija Marinko, Vladimir Kanjuh
Publikováno v:
Fundamental and Clinical Pharmacology
Hydrogen sulfide (H2 S) represents the third and the youngest member of the gaseous transmitters family. The dominant effect of H2 S on isolated vessels is vasodilation. As the mechanism of H2 S-induced relaxation in human vessels remains unclear, th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::89c3518f7758cf283edeebd6d3406054
https://doi.org/10.1111/fcp.12658
https://doi.org/10.1111/fcp.12658
Publikováno v:
Biological and Pharmaceutical Bulletin. 44:82-87
CYP epoxygenase-derived epoxyeicosatrienoic acids (EETs) contribute to endothelium-dependent hyperpolarization (EDH)-related dilation in multiple vascular beds. The present study aimed to determine the role of EETs in the acetylcholine (ACh)-induced
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5da44f63fdf19aaa7345c3d377266784
https://doi.org/10.1248/bpb.b20-00635
https://doi.org/10.1248/bpb.b20-00635