Zobrazeno 1 - 10
of 366
pro vyhledávání: '"Iber, Dagmar"'
Autor:
Vetter, Roman, Iber, Dagmar
Publikováno v:
Nat. Commun. 15, 930 (2024)
In a recent article [Vetter and Iber, Nat. Commun. 13, 1145 (2022)], we demonstrated that single morphogen gradients in the developing mouse neural tube can carry sufficient positional accuracy to explain the patterning precision of progenitor domain
Externí odkaz:
http://arxiv.org/abs/2402.00781
Publikováno v:
Computer Physics Communications 299, 109128 (2024)
We present PolyHoop, a lightweight standalone C++ implementation of a mechanical model to simulate the dynamics of soft particles and cellular tissues in two dimensions. With only few geometrical and physical parameters, PolyHoop is capable of simula
Externí odkaz:
http://arxiv.org/abs/2307.15006
Publikováno v:
In Computer Physics Communications June 2024 299
Autor:
Junyent, Sergi, Meglicki, Maciej, Vetter, Roman, Mandelbaum, Rachel, King, Catherine, Patel, Ekta M., Iwamoto-Stohl, Lisa, Reynell, Clare, Chen, Dong-Yuan, Rubino, Patrizia, Arrach, Nabil, Paulson, Richard J., Iber, Dagmar, Zernicka-Goetz, Magdalena
Publikováno v:
In Cell 23 May 2024 187(11):2838-2854
A common developmental process, called branching morphogenesis, generates the epithelial trees in a variety of organs, including the lungs, kidneys, and glands. How branching morphogenesis can create epithelial architectures of very different shapes
Externí odkaz:
http://arxiv.org/abs/2103.00258
Autor:
Iber, Dagmar
Branching morphogenesis generates epithelial trees which facilitate gas exchange, filtering, as well as secretion processes with their large surface to volume ratio. In this review, we focus on the developmental mechanisms that control the early stag
Externí odkaz:
http://arxiv.org/abs/2012.12127
Publikováno v:
In Cell Reports 26 December 2023 42(12)
Publikováno v:
In iScience 20 October 2023 26(10)
Parameter estimation is a major challenge in computational modeling of biological processes. This is especially the case in image-based modeling where the inherently quantitative output of the model is measured against image data, which is typically
Externí odkaz:
http://arxiv.org/abs/1807.10180
During organogenesis tissue grows and deforms. The growth processes are controlled by diffusible proteins, so-called morphogens. Many different patterning mechanisms have been proposed. The stereotypic branching program during lung development can be
Externí odkaz:
http://arxiv.org/abs/1710.02876