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Akademický článek

Hyperglucagonaemia and amino acid alterations in individuals with type 2 diabetes and non-alcoholic fatty liver disease

Autor: Iben Rix, Marie L Johansen, Asger Lund, Malte P Suppli, Elizaveta Chabanova, Gerrit van Hall, Jens J Holst, Nicolai J Wewer Albrechtsen, Caroline Kistorp, Filip K Knop

Publikováno v: Endocrine Connections, Vol 13, Iss 1, Pp 1-11 (2023)

Aims: Hyperglucagonaemia contributes to the pathophysiology in type 2 diabetes (T2D), but the mechanisms behind the inappropriate glucagon secretion are not fully understood. Glucagon and amino acids are regulated in a feedback loop referred to as th

Externí odkaz: https://doaj.org/article/6f1c147d2ee0469ab8bf0a86ef0c342e

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Akademický článek

Identification of bile acid-CoA:amino acid N-acyltransferase as the hepatic N-acyl taurine synthase for polyunsaturated fatty acids

Autor: Samuel A.J. Trammell, Luke F. Gamon, Kamil Gotfryd, Katja Thorøe Michler, Bandar D. Alrehaili, Iben Rix, Filip K. Knop, Pontus Gourdon, Yoon-Kwang Lee, Michael J. Davies, Matthew P. Gillum, Trisha J. Grevengoed

Publikováno v: Journal of Lipid Research, Vol 64, Iss 9, Pp 100361- (2023)

N-acyl taurines (NATs) are bioactive lipids with emerging roles in glucose homeostasis and lipid metabolism. The acyl chains of hepatic and biliary NATs are enriched in polyunsaturated fatty acids (PUFAs). Dietary supplementation with a class of PUFA

Externí odkaz: https://doaj.org/article/f84f1e3b40024fd5a3352b3eef7e65dc

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1191-P: Increased Glucagon Sensitivity in Totally Pancreatectomized Patients

Autor: Iben Rix, Lars F. Garvey, Jens J. Holst, Tina Vilsbøll, Filip K. Knop, Asger Lund, Gerrit van Hall, Carsten P. Hansen, Klara Owen

Publikováno v: Diabetes. 70

Glucagon secretion and signaling are affected in several metabolic disorders including different types of diabetes. To understand these mechanisms better, we investigated the effect of exogeneous glucagon in participants deprived of endogenous glucag

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::8354d7a574dd6c9133583275e1cb4e0f
https://doi.org/10.2337/db21-1191-p

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Cardiometabolic effects of antidiabetic drugs in non-alcoholic fatty liver disease

Autor: Heidi Storgaard, Iben Rix, Lise Lotte Gluud, Julie Steen Pedersen

Publikováno v: Clinical Physiology and Functional Imaging. 39:122-127

PURPOSE Non-alcoholic fatty liver disease (NAFLD) affects about 25% of the population worldwide. NAFLD may be viewed as the hepatological manifestation of metabolic syndrome. Patients with metabolic syndrome due to diabetes or obesity have an increas

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e7f5c688c34f457f9f3a0570ab91266d
https://doi.org/10.1111/cpf.12526

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The Scandinavian baltic pancreatic club (SBPC) database: design, rationale and characterisation of the study cohort

Publikováno v: Olesen, S M, Poulsen, J L, Drewes, A M, Frøkjær, J B, Laukkarinen, J, Parhiala, M, Rix, I, Novovic, S, Lindkvist, B, Bexander, L, Dimcevski, G, Engjom, T, Erchinger, F, Haldorsen, I S, Pukitis, A, Ozola-Zālīte, I, Haas, S, Vujasinovic, M, Löhr, J-M, Gulbinas, A, Jensen, N M, Jørgensen, M T, Nøjgaard, C & Scandinavian Baltic Pancreatic Club (SBPC) 2017, ' The Scandinavian baltic pancreatic club (SBPC) database : design, rationale and characterisation of the study cohort ', Scandinavian Journal of Gastroenterology, vol. 52, no. 8, pp. 909-915 . https://doi.org/10.1080/00365521.2017.1322138
Olesen, S S, Poulsen, J L, Drewes, A M, Frøkjær, J B, Laukkarinen, J, Parhiala, M, Rix, I, Novovic, S, Lindkvist, B, Bexander, L, Dimcevski, G, Engjom, T, Erchinger, F, Haldorsen, I S, Pukitis, A, Ozola-Zālīte, I, Haas, S, Vujasinovic, M, Löhr, J-M, Gulbinas, A, Jensen, N M, Jørgensen, M T, Nøjgaard, C & Scandinavian Baltic Pancreatic Club (SBPC) 2017, ' The Scandinavian baltic pancreatic club (SBPC) database : design, rationale and characterisation of the study cohort ', Scandinavian Journal of Gastroenterology, vol. 52, no. 8, pp. 909-915 . https://doi.org/10.1080/00365521.2017.1322138

OBJECTIVES: Chronic pancreatitis (CP) is a multifaceted disease associated with several risk factors and a complex clinical presentation. We established the Scandinavian Baltic Pancreatic Club (SBPC) Database to characterise and study the natural his

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9cc01126e924988bad31ad572a57b15b
https://pubmed.ncbi.nlm.nih.gov/28471312

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Asthma in ear, nose, and throat primary care patients with chronic rhinosinusitis with nasal polyps

Autor: Vibeke Backer, Christian von Buchwald, Andreas T Ravn, Susanne Schwer, Kåre Håkansson, Martin Frendø, Iben Rix

Publikováno v: American journal of rhinologyallergy. 30(3)

Background Chronic rhinosinusitis with nasal polyps (CRSwNP) is a common inflammatory disorder associated with asthma. This association is well described in patients with CRSwNP undergoing endoscopic sinus surgery (ESS); however, some patients are ne

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3dd51d2a32df11fcc001260ba8542922
https://pubmed.ncbi.nlm.nih.gov/27216338

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Management of chronic rhinosinusitis with nasal polyps and coexisting asthma: A systematic review

Autor: Kåre Håkansson, Martin Frendø, Iben Rix, Christian Grønhøj Larsen, Christian von Buchwald

Publikováno v: American journal of rhinologyallergy. 29(3)

Background Chronic rhinosinusitis (CRS) with nasal polyps (CRSwNP) and asthma are strongly associated, and patients suffering from both diseases are often difficult to treat. However, no guidelines about the management of patients with CRS and coexis

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6442278e8210e1bef84b2b3018a3268c
https://pubmed.ncbi.nlm.nih.gov/25975250

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