Zobrazeno 1 - 10
of 46
pro vyhledávání: '"Iben Lundgaard"'
Autor:
Gabriela C. De Paula, Blanca I. Aldana, Roberta Battistella, Rosalía Fernández-Calle, Andreas Bjure, Iben Lundgaard, Tomas Deierborg, João M. N. Duarte
Publikováno v:
Journal of Neuroinflammation, Vol 21, Iss 1, Pp 1-16 (2024)
Abstract Dietary patterns that include an excess of foods rich in saturated fat are associated with brain dysfunction. Although microgliosis has been proposed to play a key role in the development of brain dysfunction in diet-induced obesity (DIO), n
Externí odkaz:
https://doaj.org/article/f63b0eba36e841d9b3c65e1eea50c764
Autor:
Marta Ramos-Vega, Pontus Kjellman, Mihail Ivilinov Todorov, Tekla Maria Kylkilahti, B. Thomas Bäckström, Ali Ertürk, Chris Denis Madsen, Iben Lundgaard
Publikováno v:
Acta Neuropathologica Communications, Vol 10, Iss 1, Pp 1-13 (2022)
Abstract Recent studies suggest that metabolic changes and oxygen deficiency in the central nervous system play an important role in the pathophysiology of multiple sclerosis (MS). In our present study, we investigated the changes in oxygenation and
Externí odkaz:
https://doaj.org/article/c66cb17ff0514cfeb54eda293a879346
Autor:
Tomas Bohr, Poul G. Hjorth, Sebastian C. Holst, Sabina Hrabětová, Vesa Kiviniemi, Tuomas Lilius, Iben Lundgaard, Kent-Andre Mardal, Erik A. Martens, Yuki Mori, U. Valentin Nägerl, Charles Nicholson, Allen Tannenbaum, John H. Thomas, Jeffrey Tithof, Helene Benveniste, Jeffrey J. Iliff, Douglas H. Kelley, Maiken Nedergaard
Publikováno v:
iScience, Vol 25, Iss 9, Pp 104987- (2022)
Summary: We review theoretical and numerical models of the glymphatic system, which circulates cerebrospinal fluid and interstitial fluid around the brain, facilitating solute transport. Models enable hypothesis development and predictions of transpo
Externí odkaz:
https://doaj.org/article/33ffdd5decaa48649e91d28e1138f5aa
Publikováno v:
BMC Veterinary Research, Vol 17, Iss 1, Pp 1-8 (2021)
Abstract Background We report the effects of the presentation of an idiopathic subdural hematoma (SDH) in an adult domestic pig on the glymphatic system, a brain-wide solute clearance system. This accidental finding is based on our recently published
Externí odkaz:
https://doaj.org/article/6c4f58e52fcd4709a394c0accaa2b34b
Publikováno v:
Journal of Neuroinflammation, Vol 18, Iss 1, Pp 1-13 (2021)
Abstract Background The exchange of cerebrospinal (CSF) and interstitial fluid is believed to be vital for waste clearance in the brain. The sleep-dependent glymphatic system, which is comprised of perivascular flow of CSF and is largely dependent on
Externí odkaz:
https://doaj.org/article/feccedfae79b4477a885f299a3120139
Autor:
Jane Fisher, Chiara Pavan, Luisa S. Ohlmeier, Bo Nilson, Iben Lundgaard, Adam Linder, Peter Bentzer
Publikováno v:
Intensive Care Medicine Experimental, Vol 8, Iss 1, Pp 1-17 (2020)
Abstract Background Acute bacterial meningitis is a disease with a high mortality and a high incidence of neurological sequelae in survivors. There is an acute need to develop new adjuvant therapies. To ensure that new therapies evaluated in animal m
Externí odkaz:
https://doaj.org/article/2ff98d8a9a6546ce918741dac9bf9955
Autor:
Tirthankar Mohanty, Jane Fisher, Anahita Bakochi, Ariane Neumann, José Francisco Pereira Cardoso, Christofer A. Q. Karlsson, Chiara Pavan, Iben Lundgaard, Bo Nilson, Peter Reinstrup, Johan Bonnevier, David Cederberg, Johan Malmström, Peter Bentzer, Adam Linder
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-13 (2019)
Neutrophils play critical roles in the host response to bacteria, including the production neutrophil extracellular traps (NET). Here the authors show that NET formation in the context of pneumococcal meningitis impairs bacterial clearance and target
Externí odkaz:
https://doaj.org/article/b07c86bc32944286b1715bc59d4fafda
Autor:
Theodosia Vallianatou, Nicholas B. Bèchet, Mario S. P. Correia, Iben Lundgaard, Daniel Globisch
Publikováno v:
Metabolites, Vol 12, Iss 1, p 21 (2021)
Sleep is a state in which important restorative and anabolic processes occur. Understanding changes of these metabolic processes during the circadian rhythm in the brain is crucial to elucidate neurophysiological mechanisms important for sleep functi
Externí odkaz:
https://doaj.org/article/17097f0fc6654f56a7d800543ddba3a8
Autor:
Roberta Battistella, Marios Kritsilis, Hana Matuskova, Douglas Haswell, Anne Xiaoan Cheng, Anja Meissner, Maiken Nedergaard, Iben Lundgaard
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 21, p 11554 (2021)
The vascular system is vital for all tissues and the interest in its visualization spans many fields. A number of different plant-derived lectins are used for detection of vasculature; however, studies performing direct comparison of the labeling eff
Externí odkaz:
https://doaj.org/article/2775e13ac7734fd68eea1e35fd93b552
Autor:
Anne Sofie Munk, Wei Wang, Nicholas Burdon Bèchet, Ahmed M. Eltanahy, Anne Xiaoan Cheng, Björn Sigurdsson, Abdellatif Benraiss, Maarja A. Mäe, Benjamin Travis Kress, Douglas H. Kelley, Christer Betsholtz, Kjeld Møllgård, Anja Meissner, Maiken Nedergaard, Iben Lundgaard
Publikováno v:
Cell Reports, Vol 26, Iss 11, Pp 2955-2969.e3 (2019)
Summary: The glymphatic system is a highly polarized cerebrospinal fluid (CSF) transport system that facilitates the clearance of neurotoxic molecules through a brain-wide network of perivascular pathways. Herein we have mapped the development of the
Externí odkaz:
https://doaj.org/article/5b77896f85a4421cba8e2c229b4cb483