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Akademický článek

The GLP-1 Analogs Liraglutide and Semaglutide Reduce Atherosclerosis in ApoE−/− and LDLr−/− Mice by a Mechanism That Includes Inflammatory Pathways

Autor: Günaj Rakipovski, PhD, Bidda Rolin, DVM, Jane Nøhr, PhD, Ib Klewe, PhD, Klaus S. Frederiksen, PhD, Robert Augustin, PhD, Jacob Hecksher-Sørensen, PhD, Camilla Ingvorsen, PhD, Joseph Polex-Wolf, PhD, Lotte Bjerre Knudsen, DMSc

Publikováno v: JACC: Basic to Translational Science, Vol 3, Iss 6, Pp 844-857 (2018)

Summary: The glucagon-like peptide-1 receptor agonists (GLP-1RAs) liraglutide and semaglutide reduce cardiovascular risk in type 2 diabetes patients. The mode of action is suggested to occur through modified atherosclerotic progression. In this study

Externí odkaz: https://doaj.org/article/2d522d42a8bd4b7390f2d85e3fee3cac

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The GLP-1 Analogs Liraglutide and Semaglutide Reduce Atherosclerosis in ApoE−/− and LDLr−/− Mice by a Mechanism That Includes Inflammatory Pathways

Autor: Robert Augustin, Lotte Bjerre Knudsen, Klaus Stensgaard Frederiksen, Jane Nøhr, Ib Klewe, Joseph Polex-Wolf, Günaj Rakipovski, Bidda Rolin, Camilla Ingvorsen, Jacob Hecksher-Sørensen

Publikováno v: JACC: Basic to Translational Science
JACC: Basic to Translational Science, Vol 3, Iss 6, Pp 844-857 (2018)

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Highlights • The GLP-1RAs liraglutide and semaglutide reduce cardiovascular risk in type 2 diabetes patients. • In ApoE−/− mice and LDLr−/− mice, liraglutide and semaglutide treatment significantly attenuated plaque l

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6a2285f7b2f401e31c02827d624d53aa
http://europepmc.org/articles/PMC6314963

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Anomalous Transport in Conical Granular Piles

Autor: Álvaro Corral, Mikkel Avlund, Peter Toke Heden Ahlgren, Jonas Nyvold Pedersen, Ib Klewe

Experiments on 2+1-dimensional piles of elongated particles are performed. Comparison with previous experiments in 1+1 dimensions shows that the addition of one extra dimension to the dynamics changes completely the avalanche properties, appearing a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2c508700db4890ab5513191612d33c85

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