Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Iara J. de Messias Reason"'
Autor:
Elidiana De Bona, Kárita Cláudia Freitas Lidani, Lorena Bavia, Zahra Omidian, Luiza Helena Gremski, Thaisa Lucas Sandri, Iara J. de Messias Reason
Publikováno v:
Frontiers in Immunology, Vol 9 (2018)
Chagas disease (CD), a neglected tropical disease caused by the protozoan Trypanosoma cruzi, affects around six million individuals in Latin America. Currently, CD occurs worldwide, becoming a significant public health concern due to its silent aspec
Externí odkaz:
https://doaj.org/article/73586cb238a14ea1b1debf3db305f442
Autor:
Maria Regina Tizzot, Kárita Cláudia Freitas Lidani, Fabiana Antunes Andrade, Hellen Weinschutz Mendes, Marcia Holsbach Beltrame, Edna Reiche, Steffen Thiel, Jens C. Jensenius, Iara J. de Messias-Reason
Publikováno v:
Frontiers in Immunology, Vol 9 (2018)
The complement system is a key component of the innate immune system, participating in the surveillance against infectious agents. Once activated by one of the three different pathways, complement mediates cell lysis, opsonization, signalizes pathoge
Externí odkaz:
https://doaj.org/article/d2ad2e0278b54af88da397f4881be77e
Publikováno v:
Frontiers in Microbiology, Vol 8 (2017)
Trypanosoma cruzi is a protozoan parasite known to cause Chagas disease (CD), a neglected sickness that affects around 6–8 million people worldwide. Originally, CD was mainly found in Latin America but more recently, it has been spread to countries
Externí odkaz:
https://doaj.org/article/7913ec1f18644a41a92a89ff3ed4cbb9
Publikováno v:
Memorias do Instituto Oswaldo Cruz, Vol 109, Iss 4, Pp 442-447 (2014)
The aim of the present study was to detect natural infection by Leishmania (Leishmania) infantum in Lutzomyia longipalpis captured in Barcarena, state of Pará, Brazil, through the use of three primer sets. With this approach, it is unnecessary to pr
Externí odkaz:
https://doaj.org/article/01aaabb2e2104919a3a9e1ac433925ee
Human complement receptor type 1 (CR1) protein levels and genetic variants in chronic Chagas Disease
Autor:
Thaisa Lucas, Sandri, Kárita Cláudia Freitas, Lidani, Fabiana Antunes, Andrade, Christian G, Meyer, Peter G, Kremsner, Iara J, de Messias-Reason, Thirumalaisamy P, Velavan
Publikováno v:
Scientific Reports
Scientific Reports, Vol 8, Iss 1, Pp 1-10 (2018)
Scientific Reports, Vol 8, Iss 1, Pp 1-10 (2018)
Complement is an essential element in both innate and acquired immunity contributing to the immunopathogenesis of many disorders, including Chagas Disease (CD). Human complement receptor 1 (CR1) plays a role in the clearance of complement opsonized m
Publikováno v:
Clinical and Experimental Immunology. 145:463-468
SummaryMannan-binding lectin (MBL) is an important component of the first-line defence against infections. Evidence has shown that MBL deficiency, reducing phagocytosis and internalization of intracellular pathogens may protect the host against intra
Publikováno v:
North American Journal of Medical Sciences
Background: Endemic pemphigus foliaceus (EPF) is the only known autoimmune disease presenting in circumscribed geographic areas. Aim: We aim to provide information concerning the natural course of EPF, including systemic compromise in the presteroid
Autor:
Iara J. de Messias-Reason, Segun I. Oyedeji, Imad Faik, Peter G. Kremsner, Zulkarnain Md Idris, Jürgen F. J. Kun, Bertrand Lell
Publikováno v:
Human immunology. 72(1)
Human ficolin-2 (L-ficolin; FCN2) is a serum protein binding to sugar moieties of different human micro-pathogens forcing phagocytosis. Here, we investigate the clinical significance of FCN2 in African children with either mild or severe malaria (n =
Publikováno v:
The Journal of infectious diseases. 199(6)
Host factors have been shown to play a significant role in the susceptibility to and clinical outcome of leprosy. Here, we analyze polymorphisms of the gene encoding ficolin-2 (FCN2), which is a soluble pattern-recognition molecule. A total of 158 pa
Autor:
Cristina, Tena-Tomás, Maria Lucia, Pedroso, Iara J, de Messias-Reason, Peter G, Kremsner, Jürgen F J, Kun
Publikováno v:
European cytokine network. 18(3)
Interferon-alpha (IFN-alpha) alone or in combination with ribavirin has been used for the last decade in the treatment of chronic hepatitis C, although the achievement of a sustained virological response (SVR) has not been very satisfactory. The trea