Zobrazeno 1 - 10
of 76
pro vyhledávání: '"Iannis E Adamopoulos"'
Autor:
Adam P Ross, M Adela Mansilla, Youngshik Choe, Simon Helminski, Richard Sturm, Roy L Maute, Scott R May, Kamil K Hozyasz, Piotr Wójcicki, Adrianna Mostowska, Beth Davidson, Iannis E Adamopoulos, Samuel J Pleasure, Jeffrey C Murray, Konstantinos S Zarbalis
Publikováno v:
PLoS ONE, Vol 8, Iss 7, p e69333 (2013)
Orofacial clefts are among the most common birth defects and result in an improper formation of the mouth or the roof of the mouth. Monosomy of the distal aspect of human chromosome 6p has been recognized as causative in congenital malformations affe
Externí odkaz:
https://doaj.org/article/3455b107f3fe46c88b568ef09eda1336
Autor:
Alexander Merleev, Antonio Ji-Xu, Atrin Toussi, Lam C. Tsoi, Stephanie T. Le, Guillaume Luxardi, Xianying Xing, Rachael Wasikowski, William Liakos, Marie-Charlotte Brüggen, James T. Elder, Iannis E. Adamopoulos, Yoshihiro Izumiya, Annie R. Leal, Qinyuan Li, Nikolay Y. Kuzminykh, Amanda Kirane, Alina I. Marusina, Johann E. Gudjonsson, Emanual Maverakis
Publikováno v:
JCI Insight, Vol 7, Iss 16 (2022)
Proprotein convertase subtilisin/kexin type-9 (PCSK9) is a posttranslational regulator of the LDL receptor (LDLR). Recent studies have proposed a role for PCSK9 in regulating immune responses. Using RNA-Seq–based variant discovery, we identified a
Externí odkaz:
https://doaj.org/article/0af5f0392e5144bb91cb11d1e06f87ed
Autor:
Alexander A. Merleev, Stephanie T. Le, Claire Alexanian, Atrin Toussi, Yixuan Xie, Alina I. Marusina, Steven M. Watkins, Forum Patel, Allison C. Billi, Julie Wiedemann, Yoshihiro Izumiya, Ashish Kumar, Ranjitha Uppala, J. Michelle Kahlenberg, Fu-Tong Liu, Iannis E. Adamopoulos, Elizabeth A. Wang, Chelsea Ma, Michelle Y. Cheng, Halani Xiong, Amanda Kirane, Guillaume Luxardi, Bogi Andersen, Lam C. Tsoi, Carlito B. Lebrilla, Johann E. Gudjonsson, Emanual Maverakis
Publikováno v:
JCI Insight, Vol 7, Iss 16 (2022)
The epidermis is the outermost layer of skin. Here, we used targeted lipid profiling to characterize the biogeographic alterations of human epidermal lipids across 12 anatomically distinct body sites, and we used single-cell RNA-Seq to compare kerati
Externí odkaz:
https://doaj.org/article/29f7b5c3c7314462ae63385c896e06c5
Autor:
Hao Li, Iannis E. Adamopoulos, Vaishali R. Moulton, Isaac E. Stillman, Zach Herbert, James J. Moon, Amir Sharabi, Suzanne Krishfield, Maria G. Tsokos, George C. Tsokos
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-12 (2020)
Splenic marginal zone macrophages can establish immune tolerance and limit the development of systemic lupus erythematosus (SLE). Here the authors show that these cells do this by clearing apoptotic cells, and defects in these cells result in the gen
Externí odkaz:
https://doaj.org/article/e6b55468c2854d60ac861be67cb25f57
Publikováno v:
Frontiers in Immunology, Vol 11 (2021)
Axial spondyloarthritis is a prevalent form of chronic arthritis which is related to psoriatic arthritis and skin psoriasis. TNF and IL-17A as well as IL-17F are key cytokines contributing to the pathobiology of this disease, as evidence by the thera
Externí odkaz:
https://doaj.org/article/3f8f50c98f5c494babbe9d41f9f5c4e3
Autor:
Cuong Thach Nguyen, Hiroki Furuya, Dayasagar Das, Alina I. Marusina, Alexander A. Merleev, Resmi Ravindran, Zahra Jalali, Imran H. Khan, Emanual Maverakis, Iannis E. Adamopoulos
Publikováno v:
Arthritis & Rheumatology. 74:1524-1534
This study was undertaken to identify the mechanistic role of γδ T cells in the pathogenesis of experimental psoriatic arthritis (PsA).In this study, we performed interleukin-23 (IL-23) gene transfer in wild-type (WT) and T cell receptor δ-deficie
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eb0c7448b71129f0b7a52ca99aaef638
https://doi.org/10.1002/art.42124
https://doi.org/10.1002/art.42124
Autor:
Alina I. Marusina, Antonio Ji-Xu, Stephanie T. Le, Atrin Toussi, Lam C. Tsoi, Qinyuan Li, Guillaume Luxardi, Jordan Nava, Lauren Downing, Annie R. Leal, Nikolay Y. Kuzminykh, Olga Kruglinskaya, Marie-Charlotte Brüggen, Iannis E. Adamopoulos, Alexander A. Merleev, Johann E. Gudjonsson, Emanual Maverakis
Publikováno v:
Journal of Investigative Dermatology.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::284bf61fce130188f7b1986f1951e9c0
https://doi.org/10.1016/j.jid.2023.01.012
https://doi.org/10.1016/j.jid.2023.01.012
Publikováno v:
Clinical Immunology. 251:109327
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ce05a39a7aefade7271ce6c945e38554
https://doi.org/10.1016/j.clim.2023.109327
https://doi.org/10.1016/j.clim.2023.109327
Autor:
Iannis E. Adamopoulos, Dario Kivelevitch, Gerald G. Krueger, Richard G. Langley, Alan Menter, So Yeon Paek
Publikováno v:
Dermatology and Therapy
Psoriasis is an immune-mediated inflammatory skin disease associated with numerous inflammatory comorbidities, including increased cardiovascular risk. The interleukin (IL)-23/IL-17 axis plays a central role in the immunopathogenesis of psoriasis and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7872d48fa7f2b92718b005595a9cf0d3
https://doi.org/10.1007/s13555-021-00483-2
https://doi.org/10.1007/s13555-021-00483-2
Autor:
Shi Su, Xanthi-Lida Katopodi, Yered H. Pita-Juarez, Emanual Maverakis, Ioannis S. Vlachos, Iannis E. Adamopoulos
Publikováno v:
Clinical immunology (Orlando, Fla.). 240
Serine and Arginine Rich Splicing Factor 1 (SRSF1) is a splicing factor that binds to exonic enhancers and stimulates splicing and is previously implicated with autoimmunity. Herein, we investigate the role of SRSF1 in regulating innate immune functi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::127c899313ee39b9af29ccf45dd7fe04
https://pubmed.ncbi.nlm.nih.gov/35613697
https://pubmed.ncbi.nlm.nih.gov/35613697