Výsledky vyhledávání - "Ian Waterson"

Toxicology Paradise: Sorting Out Adverse and Non-adverse Findings in Animal Toxicity Studies

Autor: Brad Bolon, Paul Baldrick, Tessie Alapatt, Melissa Rhodes, Mary Ellen Cosenza, Ian Waterson

Publikováno v: International Journal of Toxicology. 39:365-378

A challenge for all toxicologists is defining what study findings are actually adverse versus non-adverse in animal toxicity studies, and which ones are relevant for generating a no observed adverse effect level (NOAEL) to assess human risk. This art

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::0a52882a93d93b2d5544880a835643e9
https://doi.org/10.1177/1091581820935089

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Preclinical screening for antidepressant activity - shifting focus away from the Forced Swim Test to the use of translational biomarkers

Autor: Ian Ragan, Fiona Sewell, David Jones, Ian Waterson, Mark D. Tricklebank

Publikováno v: Regulatory toxicology and pharmacology : RTP. 125

Depression is the world's predominant mental health problem and a leading cause of disability. Neuropharmacological research has not yet advanced treatments to sufficiently meet clinical need, largely due to the failure of animal models to predict cl

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f81ff50c5df8ff88296a771cc3694db1
https://pubmed.ncbi.nlm.nih.gov/34245825

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