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pro vyhledávání: '"Ian W. Kellaway"'
Autor:
Ian W. Kellaway
Publikováno v:
Smith and Williams' Introduction to the Principles of Drug Design and Action ISBN: 9781315273792
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e50d9fa1916d2f70849f5c4f34ab1af1
https://doi.org/10.1201/9781315273792-2
https://doi.org/10.1201/9781315273792-2
Publikováno v:
International Journal of Pharmaceutics. 375:114-122
Nanoparticles containing insulin have been produced by emulsification processes followed by freeze-drying. Purified nanoparticles were suspended in hydrofluoroalkane (HFA) 134a, using essential oils (cineole and citral) as suspension stabilizers to f
Publikováno v:
International Journal of Pharmaceutics. 372:140-146
Nanoparticles delivered from pressurized metered dose inhalers (pMDIs) potentially offer a means of efficiently delivering proteins to the lung. Nanoparticles containing the model protein lysozyme have been produced using microemulsion and nanoprecip
Publikováno v:
Langmuir. 21:7342-7348
The effect of pH on the adsorption of catalase and lysozyme at the air-water interface has been studied using a combined surface pressure-interfacial shear rheology technique. The results presented show that the rate of development of interfacial phe
Publikováno v:
Journal of Controlled Release. 104:79-90
A novel process for generating sustained release (SR) particles for pulmonary drug delivery is described. High purity nanoparticles of a hydrophilic, ionised drug are entrapped within hydrophobic microspheres using a spray-drying approach. Sustained
Publikováno v:
Journal of Pharmacy and Pharmacology. 53:629-636
The possible role of water inthe mucoadhesion phenomenon exhibitedby the liquid crystalline phases of glyceryl monooleate was investigated using an in-vitro tensile strength technique. The mucoadhesion of the liquid crystalline phases of glyceryl mon
Autor:
Ian W. Kellaway, Y Darwis
Publikováno v:
International Journal of Pharmaceutics. 215:113-121
Beclomethasone dipropionate (BDP) liposomes were prepared from various lipids, dilauroyl phosphatidylcholine (DLPC), dimyristoyl phosphatidylcholine (DMPC), dipalmitoyl phosphatidylcholine (DPPC), and hydrogenated soybean phosphatidylcholine (Epikuro
Publikováno v:
International Journal of Pharmaceutics. 197:221-231
The lower respiratory tract provides a number of disease targets for gene therapy. Nebulisation is the most practical system for the aerosolisation of non-viral gene delivery systems. The aerosolisation process represents a significant challenge to t
Publikováno v:
International Journal of Pharmaceutics. 195:17-23
Current literature highlights the potential suitability of microcalorimetry for the investigation of cell-drug interactions. Previous work using bacteria or antigens derived from infectious organisms yielded conclusions that heat production is a quan
Autor:
Jaehwi Lee, Ian W. Kellaway
Publikováno v:
International Journal of Pharmaceutics. 195:29-33
Swelling and [D-Ala(2), D-Leu(5)]enkephalin (DADLE) release from the lamellar and cubic liquid crystalline phases of glyceryl monooleate (GMO) were studied using two in vitro methods, a total immersion method and a Franz cell method. The swelling of