Zobrazeno 1 - 10
of 40
pro vyhledávání: '"Ian W. James"'
Publikováno v:
Angewandte Chemie. International Edition; September 3, 2001, Vol. 40 Issue: 17 p3230-3233, 4p
Autor:
Rustum S. Boyce, Jonathan M. White, Andrew M. Bray, Ian W. James, Craig S. Sheehan, Thao Nguyen, Sharon T. Marino, Beata M. Krywult, Daniel A. Huggins, Peter G. Griffiths, Neil Choi, Danuta Stachurska-Buczek, Jack G. Parsons
Publikováno v:
Molecules, Vol 9, Iss 6, Pp 449-458 (2004)
The synthesis of (2S)-2-benzyloxymethyl-3-(2-fluoro-4-methoxyphenyl)- propionic acid, (2S)-2-benzyloxymethyl-3-(2-fluoro-4-methylphenyl)propionic acid and (2S)-2-benzyl-oxymethyl-3-(2,4-dimethylphenyl)propionic acid has been achieved by TiCl4 mediate
Externí odkaz:
https://doaj.org/article/79972dc0ed9743ebba6459a5f9db9f31
Autor:
Rustum S. Boyce, Jonathan M. White, Andrew M. Bray, Ian W. James, Peter G. Griffiths, Jack G. Parsons, Neil Choi, Thao Nguyen, Craig S. Sheehan, Beata M. Krywult, Daniel A. Huggins, Danuta Stachurska-Buczek, Sharon T. Marino
Publikováno v:
Molecules, Vol 9, Iss 6, Pp 405-426 (2004)
In the past decade there has been a significant growth in the sales of pharmaceutical drugs worldwide, but more importantly there has been a dramatic growth in the sales of single enantiomer drugs. The pharmaceutical industry has a rising demand for
Externí odkaz:
https://doaj.org/article/4608ad3d215d4a5baa43da91d5408ca6
Autor:
Daniel A. Huggins, Jonathan M. White, Sharon T. Marino, Peter G. Griffiths, Andrew M. Bray, Thao Nguyen, Ian W. James, Craig S. Sheehan, Beata Krywult, Danuta Stachurska-Buczek, Neil Choi, Rustum S. Boyce, Jack G. Parsons
Publikováno v:
Molecules
Volume 9
Issue 6
Pages: 405-426
Molecules, Vol 9, Iss 6, Pp 405-426 (2004)
Volume 9
Issue 6
Pages: 405-426
Molecules, Vol 9, Iss 6, Pp 405-426 (2004)
In the past decade there has been a significant growth in the sales of pharmaceutical drugs worldwide, but more importantly there has been a dramatic growth in the sales of single enantiomer drugs. The pharmaceutical industry has a rising demand for
Autor:
Lawrence D'Souza, Ramina Nazarbaghi, Uday Maitra, Nicholas J. Ede, Yazhong Pei, Walter H. Moos, Susan Glasco, Xiao-Qing Tang, Ian W. James, Srinivasan Chandrasekaran, Soumitra Ghosh, Andrew N. Hunter, David J. Owen, Michael J Lilly, Jinghua Yu, Christen M. Anderson
Publikováno v:
The Journal of Organic Chemistry. 68:92-103
Type II diabetes mellitus is a chronic metabolic disorder that can lead to serious cardiovascular, renal, neurologic, and retinal complications. While several drugs are currently prescribed to treat type II diabetes, their efficacy is limited by mech
Synthesis of hydroxamic acids using SynPhase™ crowns: Development of the hydroxylamine trityl linker
Autor:
Wayne R. Sampson, Jeffrey A. Leitch, Ben Gubbins, Beata Krywult, Susan N. Eagle, Nicholas J. Ede, Andrew M. Bray, Ian W. James, Rachael M. Griffiths
Publikováno v:
Letters in Peptide Science. 6:157-163
The synthesis of peptide and small molecule hydroxamic acids utilising SynPhase™ crowns is demonstrated. A hydroxylamine trityl linker is generated from chlorotrityl derivatised Synphase™ crowns by reaction with N-hydroxyphthalimide followed by s
Autor:
Ian W. James
Publikováno v:
Tetrahedron. 55:4855-4946
Autor:
Ian W. James
Publikováno v:
Molecular Diversity. 2:175-180
Recent literature in solid-phase organic and inorganic chemistry has been reviewed. Papers have been collated according to the compounds prepared on the solid phase and the types of transformations performed. Covered are more than 40 chemical transfo
Autor:
Ian W. James
Publikováno v:
Molecular Diversity. 3:181-190
The solid phase chemistry literature for much of 1997 has been reviewed with an emphasis on organic chemistry. Reactions have been classified according to both the types of chemistry performed and the products formed on the solid phase. Examples of i
Publikováno v:
Tetrahedron Letters. 37:9097-9100
A method has been developed for the synthesis of Hmb protected amino acid residues via reductive alkylation of 2-hydroxy-4-methoxybenzaldehyde with resin bound amino acids/peptides. The methodology potentially allows incorporation of Hmb protected am