Zobrazeno 1 - 10
of 116
pro vyhledávání: '"Ian W, Gibson"'
Redefining Renal Cell Carcinoma: A Molecular Perspective on Classification and Clinical Implications
Publikováno v:
European Medical Journal, Pp 116-123 (2023)
Renal cell carcinoma (RCC) is the most common primary tumour of the kidney. RCC is a clinically and pathologically heterogenous entity, which has traditionally been classified under two broad categories: clear-cell and non-clear cell. With improved m
Externí odkaz:
https://doaj.org/article/be8229deb0d84021a486d08e9591798a
Autor:
Zeguo Sun, Zhongyang Zhang, Khadija Banu, Ian W. Gibson, Robert B. Colvin, Zhengzi Yi, Weijia Zhang, Bony De Kumar, Anand Reghuvaran, John Pell, Thomas D. Manes, Arjang Djamali, Lorenzo Gallon, Philip J. O’Connell, John Cijiang He, Jordan S. Pober, Peter S. Heeger, Madhav C. Menon
Publikováno v:
The Journal of Clinical Investigation, Vol 133, Iss 21 (2023)
Donor-recipient (D-R) mismatches outside of human leukocyte antigens (HLAs) contribute to kidney allograft loss, but the mechanisms remain unclear, specifically for intronic mismatches. We quantified non-HLA mismatches at variant-, gene-, and genome-
Externí odkaz:
https://doaj.org/article/1062a57a1df84d2eb0cec1a6f8b62c10
Publikováno v:
Canadian Journal of Kidney Health and Disease, Vol 10 (2023)
Background: Glomerulonephritis (GN) represents a common cause of chronic kidney disease, and treatment to slow or prevent progression of GN is associated with significant morbidity. Large patient registries have improved the understanding of risk str
Externí odkaz:
https://doaj.org/article/d395c4fba1fe45adbee7978c6e5c8574
Autor:
Donald E. Hricik, Brian Armstrong, Tarek Alhamad, Daniel C. Brennan, Jonathan S. Bromberg, Suphamai Bunnapradist, Sindhu Chandran, Robert. L. Fairchild, David P. Foley, Richard Formica, Ian W. Gibson, Karen Kesler, S. Joseph Kim, Roslyn B. Mannon, Madhav C. Menon, Kenneth A. Newell, Peter Nickerson, Jonah Odim, Emilio D. Poggio, Randall Sung, Ron Shapiro, Kathryn Tinckam, Flavio Vincenti, Peter S. Heeger
Publikováno v:
Journal of the American Society of Nephrology. 34:145-159
Autor:
Ian W. Gibson
Publikováno v:
Glomerular Diseases. 1:68-81
Background: Transplant glomerulopathy (TG) is a morphologic alteration in glomeruli of renal allografts, characterized by glomerular basement membrane reduplications. Summary: TG is associated with progressive chronic allograft dysfunction and protei
Autor:
Ian W. Gibson, Jeff Saranchuk, Karl Kassier, Seyed Mohammad Mohaghegh Poor, Janetta Rossouw, Robert Wightman, Shivani Mathur
Publikováno v:
International Journal of Surgical Pathology
Two sporadic cases of eosinophilic solid and cystic renal cell carcinoma (ESC RCC), at our institution, are presented in this study to contribute to the growing literature on this novel renal neoplasm. The first patient was a 38-year-old female with
Autor:
Robert Balshaw, Nancy D. Bridges, Ian W. Gibson, Julie Ho, Chris Wiebe, Peter Nickerson, David N. Rush, Peter S. Heeger
Publikováno v:
American Journal of Transplantation
Improving long‐term kidney transplant outcomes requires novel treatment strategies, including delayed calcineurin inhibitor (CNI) substitution, tested using informative trial designs. An alternative approach to the usual superiority‐based trial i
Autor:
Ian W. Gibson, Peter Nickerson, Julie Ho, Denise Pochinco, David N. Rush, Aviva Goldberg, Jamie Shaw, Chris Wiebe, Tom Blydt-Hansen, Martin Karpinski, Patricia E. Birk
Publikováno v:
American Journal of Transplantation
Prognostic biomarkers of T cell–mediated rejection (TCMR) have not been adequately studied in the modern era. We evaluated 803 renal transplant recipients and correlated HLA‐DR/DQ molecular mismatch alloimmune risk categories (low, intermediate,
Autor:
David N. Rush, James Shaw, Chris Wiebe, Ian W. Gibson, Julie Ho, Christie Rampersad, Peter Nickerson
Publikováno v:
American Journal of Kidney Diseases. 75:138-143
Improving precision in predicting alloreactivity is an important unmet need and may require individualized consideration of non-HLA antibodies. We report a 21-year-old man with kidney failure from immunoglobulin A nephropathy who met all traditional
Autor:
Yong Jia, Seyed M.M. Poor, Brenden Dufault, Vivian Lu, Jasmir G. Nayak, Deepak K. Pruthi, Ian W. Gibson
Publikováno v:
Human pathology. 124
To establish a systematic histological assessment of non-neoplastic kidney (NNK) tissue at the time of nephrectomy to evaluate a patient's risk of developing post-operative renal dysfunction, a combined prospective pathologic assessment of the NNK an