Zobrazeno 1 - 10
of 24
pro vyhledávání: '"Ian T Foe"'
Autor:
Megan Garland, Christopher J Schulze, Ian T Foe, Wouter A van der Linden, Matthew A Child, Matthew Bogyo
Publikováno v:
PLoS ONE, Vol 13, Iss 1, p e0190255 (2018)
Protein palmitoylation is a dynamic post-translational modification (PTM) important for cellular functions such as protein stability, trafficking, localization, and protein-protein interactions. S-palmitoylation occurs via the addition of palmitate t
Externí odkaz:
https://doaj.org/article/e5d8492e87b545fe8500288befcbf7ae
Autor:
John C. K. Wang, Hannah T. Baddock, Amirhossein Mafi, Ian T. Foe, Matthew Bratkowski, Ting-Yu Lin, Zena D. Jensvold, Magdalena Preciado López, David Stokoe, Dan Eaton, Qi Hao, Aaron H. Nile
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-18 (2024)
Abstract Human papillomavirus (HPV) is a significant contributor to the global cancer burden, and its carcinogenic activity is facilitated in part by the HPV early protein 6 (E6), which interacts with the E3-ligase E6AP, also known as UBE3A, to promo
Externí odkaz:
https://doaj.org/article/01d684ed234649ecaa9a5734315b209f
Publikováno v:
mSphere, Vol 6, Iss 3 (2021)
Gliding motility plays a central role in the life cycle of T. gondii
Externí odkaz:
https://doaj.org/article/9c001115bdb04ee3a7c8dff233c97ad1
Autor:
Ian T. Foe, Ouma Onguka, Katherine Amberg-Johnson, Rikki M. Garner, Neri Amara, Wandy Beatty, Ellen Yeh, Matthew Bogyo
Publikováno v:
mSphere, Vol 3, Iss 5 (2018)
ABSTRACT Hydrolase are enzymes that regulate diverse biological processes, including posttranslational protein modifications. Recent work identified four active serine hydrolases (ASHs) in Toxoplasma gondii as candidate depalmitoylases. However, only
Externí odkaz:
https://doaj.org/article/0e40db20321c4986a54345682c61beaa
Autor:
Ian T. Foe, Ouma Onguka, Katherine Amberg-Johnson, Rikki M. Garner, Neri Amara, Wandy Beatty, Ellen Yeh, Matthew Bogyo
Publikováno v:
mSphere, Vol 3, Iss 5 (2018)
Externí odkaz:
https://doaj.org/article/855cd9dabcc64f688086c00f6dafbc15
Autor:
Micah J. Niphakis, Ouma Onguka, Stephanie M. Terrell, Piotr Cieplak, Kenneth M. Lum, Brett M. Babin, Neri Amara, Ian T. Foe, Matthew Bogyo, Markus Lakemeyer, Jonathan Z. Long
Publikováno v:
Cell Chem Biol
SummaryThe intracellular protozoan parasite Toxoplasma gondii must scavenge cholesterol and other lipids from the host to facilitate intracellular growth and replication. Enzymes responsible for neutral lipid synthesis have been identified but there
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::54046838c77237279340d57d3e2e3e69
https://doi.org/10.1101/2020.11.24.396663
https://doi.org/10.1101/2020.11.24.396663
Autor:
Nina F. Gnädig, Jonathan Z. Long, Yani Zhou, Ouma Onguka, Eranthie Weerapana, David A. Fidock, Barbara H. Stokes, Sachel Mok, Anne-Catrin Uhlemann, Stephanie M. Terrell, Kenji L. Kurita, Piotr Cieplak, Christopher J. Schulze, Tomas Yeo, Roger G. Linington, Ian T. Foe, Matthew Bogyo, Michael J. Boucher, Euna Yoo
SUMMARYSalinipostin A (Sal A) is a potent antimalarial marine natural product with an undefined mechanism of action. Using a Sal A-derived activity-based probe, we identify its targets in thePlasmodium falciparumparasite. All of the identified protei
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::213079f81ffedc83bc3c52eeab1a4ac0
Autor:
David A. Fidock, Barbara H. Stokes, Piotr Cieplak, Yani Zhou, Krittikorn Kümpornsin, Sachel Mok, Jonathan Z. Long, Euna Yoo, Kenji L. Kurita, Ian T. Foe, Matthew Bogyo, Michael J. Boucher, Nina F. Gnädig, Anne-Catrin Uhlemann, Ouma Onguka, Tomas Yeo, Roger G. Linington, Stephanie M. Terrell, Christopher J. Schulze, Marcus C. S. Lee, Eranthie Weerapana
Publikováno v:
Cell Chem Biol
Summary Salinipostin A (Sal A) is a potent antiplasmodial marine natural product with an undefined mechanism of action. Using a Sal A-derived activity-based probe, we identify its targets in the Plasmodium falciparum parasite. All of the identified p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8cd1de8040b695e68d20b488036ea2d8
https://pubmed.ncbi.nlm.nih.gov/32084335
https://pubmed.ncbi.nlm.nih.gov/32084335
Autor:
Eranthie Weerapana, Nina F. Gnädig, Barbara H. Stokes, Ian T. Foe, Kenji L. Kurita, Roger G. Linington, Anne-Catrin Uhlemann, Matthew Bogyo, Michael J. Boucher, Jonathan Z. Long, Piotr Cieplak, David A. Fidock, Ouma Onguka, Euna Yoo, Tomas Yeo, Yani Zhou, Christopher J. Schulze, Sachel Mok, Stephanie M. Terrell
Publikováno v:
SSRN Electronic Journal.
Salinipostin A (Sal A) is a potent antimalarial marine natural product with an undefined mechanism of action. Using a Sal A-derived activity-based probe, we identify its targets in the Plasmodium falciparum parasite. All of the identified proteins co
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5472207e3b51d1eedb2e3264c754fd29
https://doi.org/10.2139/ssrn.3479442
https://doi.org/10.2139/ssrn.3479442
Membrane skeletal association and post-translational allosteric regulation ofToxoplasma gondiiGAPDH1
Autor:
Rashmi Dubey, Ian T. Foe, Matthew Bogyo, Bart L. Staker, Marc-Jan Gubbels, Peter J. Myler, Huân M. Ngô
Publikováno v:
Molecular Microbiology. 103:618-634
When Toxoplasma gondii egresses from the host cell, glyceraldehyde-3-phosphate dehydrogenase 1 (GAPDH1), which is primary a glycolysis enzyme but actually a quintessential multifunctional protein, translocates to the unique cortical membrane skeleton
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::850c7917cefb19a510b09a1685f20a05
https://doi.org/10.1111/mmi.13577
https://doi.org/10.1111/mmi.13577