Zobrazeno 1 - 10
of 80
pro vyhledávání: '"Ian Storer"'
Publikováno v:
Humanities & Social Sciences Communications, Vol 11, Iss 1, Pp 1-14 (2024)
Abstract Industrial designers have a need to acquire knowledge related to physical materials and undertake activities such as materials selection and materials-driven creative design. Chinese indigenous materials (CIMs) and relevant crafts are identi
Externí odkaz:
https://doaj.org/article/a33453f7b30447e2bf9e57451103c076
Publikováno v:
Humanities & Social Sciences Communications, Vol 11, Iss 1, Pp 1-1 (2024)
Externí odkaz:
https://doaj.org/article/11fcdb97aba44a1cb9703da2d68d842d
Autor:
Gomez-Angel, Andres R., Donald, James R., Firth, James D., De Fusco, Claudia, Ian Storer, R., Cox, Daniel J., O’Brien, Peter
Publikováno v:
In Tetrahedron 12 March 2021 83
Publikováno v:
In Toxicology and Applied Pharmacology 15 February 2017 317:41-50
Autor:
Angelina R. Sekirnik, Jessica K. Reynolds, Larissa See, Joseph P. Bluck, Amy R. Scorah, Cynthia Tallant, Bernadette Lee, Katarzyna B. Leszczynska, Rachel L. Grimley, R. Ian Storer, Marta Malattia, Sara Crespillo, Sofia Caria, Stephanie Duclos, Ester M. Hammond, Stefan Knapp, Garrett M. Morris, Fernanda Duarte, Philip C. Biggin, Stuart J. Conway
Publikováno v:
ACS Chemical Biology. 17:2753-2768
TRIM33 is a member of the tripartite motif (TRIM) family of proteins, some of which possess E3 ligase activity and are involved in the ubiquitin-dependent degradation of proteins. Four of the TRIM family proteins, TRIM24 (TIF1α), TRIM28 (TIF1β), TR
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f3e2aeb12794430ed27bbc1291d39218
https://doi.org/10.1021/acschembio.2c00266
https://doi.org/10.1021/acschembio.2c00266
Autor:
Benjamin C. Whitehurst, Matthias R. Bauer, Fredrik Edfeldt, Anders Gunnarsson, Christian Margreitter, Philip B. Rawlins, R. Ian Storer
Publikováno v:
Journal of Medicinal Chemistry.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::92ac4872dc5340487462910b8549354e
https://doi.org/10.1021/acs.jmedchem.3c00493
https://doi.org/10.1021/acs.jmedchem.3c00493
Autor:
Caroline L. Benn, Pinky Dua, Rachel Gurrell, Peter Loudon, Andrew Pike, R. Ian Storer, Ciara Vangjeli
Publikováno v:
Frontiers in Medicine, Vol 5 (2018)
Gout is the most common form of inflammatory arthritis and is a multifactorial disease typically characterized by hyperuricemia and monosodium urate crystal deposition predominantly in, but not limited to, the joints and the urinary tract. The preval
Externí odkaz:
https://doaj.org/article/74db2acb93c54e4eb7d0dcaff4767766
Autor:
Simon C. C. Lucas, Ulf Börjesson, Mark J. Bostock, John Cuff, Fredrik Edfeldt, Kevin J. Embrey, Per-Olof Eriksson, Andrea Gohlke, Anders Gunnarson, Michael Lainchbury, Alexander G. Milbradt, Rachel Moore, Philip B. Rawlins, Ian Sinclair, Christopher Stubbs, R. Ian Storer
Publikováno v:
RSC Med Chem
Fragment based drug discovery is a critical part of the lead generation toolbox and relies heavily on a readily available, high quality fragment library. Over years of use, the AstraZeneca fragment set had become partially depleted and instances of c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::446ddff84fa8641f08a20b101425dc2e
https://europepmc.org/articles/PMC9491351/
https://europepmc.org/articles/PMC9491351/
Autor:
Lena Ripa, Josefine Pemberton, Fredrik Edfeldt, Ulf Börjesson, Magnus Nilsson, R. Ian Storer, Paolo Di Fruscia, Gavin W. Collie, Louise Barlind, Anna Aagaard, Linda Öster, Helena Käck, Eva L. Hansson, Igor L. Shamovsky, Richard J. Lewis
Publikováno v:
ACS Med Chem Lett
[Image: see text] The MEK1 kinase plays a critical role in key cellular processes, and as such, its dysfunction is strongly linked to several human diseases, particularly cancer. MEK1 has consequently received considerable attention as a drug target,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::32e123e9ce780e990c54c74a7c8c4a07
https://doi.org/10.1021/acsmedchemlett.0c00563
https://doi.org/10.1021/acsmedchemlett.0c00563
Autor:
Jennifer E. Nelson, Simon C. C. Lucas, Iacovos N Michaelides, Matthias R. Bauer, Benjamin C Whitehurst, R. Ian Storer, Paolo Di Fruscia
Publikováno v:
RSC Med Chem
Aliphatic three- and four-membered rings including cyclopropanes, cyclobutanes, oxetanes, azetidines and bicyclo[1.1.1]pentanes have been increasingly exploited in medicinal chemistry for their beneficial physicochemical properties and applications a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f297b29e4248cacc143b0578d2195082
https://doi.org/10.1039/d0md00370k
https://doi.org/10.1039/d0md00370k