Zobrazeno 1 - 10
of 48
pro vyhledávání: '"Ian Stoppa"'
Autor:
Alessia Provera, Cristina Vecchio, Anteneh Nigussie Sheferaw, Ian Stoppa, Deepika Pantham, Umberto Dianzani, Salvatore Sutti
Publikováno v:
Heliyon, Vol 10, Iss 15, Pp e35338- (2024)
Metabolic dysfunction associated steatotic liver disease (MASLD) is a progressive pathological condition characterized by the accumulation of triglycerides within hepatocytes that causes histological changes, which, in the long run, might compromise
Externí odkaz:
https://doaj.org/article/165392ea03ad43e38e826b1f18cedd4d
Autor:
Alessia Provera, Naresh Naik Ramavath, Laila Lavanya Gadipudi, Casimiro Luca Gigliotti, Elena Boggio, Cristina Vecchio, Ian Stoppa, Roberta Rolla, Renzo Boldorini, Mario Pirisi, Carlo Smirne, Emanuele Albano, Umberto Dianzani, Salvatore Sutti
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
Background and aimsInducible T-cell Co-Stimulator (ICOS) present on T-lymphocytes and its ligand ICOSL expressed by myeloid cells play multiple roles in regulating T-cell functions. However, recent evidence indicates that reverse signalling involving
Externí odkaz:
https://doaj.org/article/f05f4f2e19024bb6aff14a0bd147f227
Autor:
Ian Stoppa, Chiara Dianzani, Nausicaa Clemente, Annalisa Bozza, Valentina Bordano, Sara Garelli, Luigi Cangemi, Umberto Dianzani, Luigi Battaglia
Publikováno v:
Biomolecules, Vol 14, Iss 2, p 238 (2024)
Bone is a site of distant metastases, which are a common cause of morbidity and mortality with a high socio-economic impact, for many malignant tumours. In order to engineer pharmacological therapies that are suitable for this debilitating disease, t
Externí odkaz:
https://doaj.org/article/64c0d3947aa24a85969c2d506d96458c
Autor:
Gustavo Ferreira Alves, Ian Stoppa, Eleonora Aimaretti, Chiara Monge, Raffaella Mastrocola, Elisa Porchietto, Giacomo Einaudi, Debora Collotta, Ilaria Bertocchi, Elena Boggio, Casimiro Luca Gigliotti, Nausicaa Clemente, Manuela Aragno, Daniel Fernandes, Carlo Cifani, Christoph Thiemermann, Chiara Dianzani, Umberto Dianzani, Massimo Collino
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Inducible T cell co-stimulator (ICOS), an immune checkpoint protein expressed on activated T cells and its unique ligand, ICOSL, which is expressed on antigen-presenting cells and non-hematopoietic cells, have been extensively investigated in the imm
Externí odkaz:
https://doaj.org/article/1c55e496fa97413c9846216878568c2f
Autor:
Chiara Puricelli, Casimiro Luca Gigliotti, Ian Stoppa, Sara Sacchetti, Deepika Pantham, Anna Scomparin, Roberta Rolla, Stefania Pizzimenti, Umberto Dianzani, Elena Boggio, Salvatore Sutti
Publikováno v:
Pharmaceutics, Vol 15, Iss 6, p 1772 (2023)
Chronic inflammation contributes to the pathogenesis of many diseases, including apparently unrelated conditions such as metabolic disorders, cardiovascular diseases, neurodegenerative diseases, osteoporosis, and tumors, but the use of conventional a
Externí odkaz:
https://doaj.org/article/8467e4ef71cd47deb3a6df40ccb3c0ba
Autor:
Federica Costa, Eleonora Beltrami, Simona Mellone, Sara Sacchetti, Elena Boggio, Casimiro Luca Gigliotti, Ian Stoppa, Umberto Dianzani, Roberta Rolla, Mara Giordano
Publikováno v:
Biomedicines, Vol 11, Iss 4, p 1127 (2023)
Monogenic autoimmune disorders represent an important tool to understand the mechanisms behind central and peripheral immune tolerance. Multiple factors, both genetic and environmental, are known to be involved in the alteration of the immune activat
Externí odkaz:
https://doaj.org/article/1289b07fc1e44e2db079d5c833c339cb
Autor:
Elena Boggio, Casimiro Luca Gigliotti, Ian Stoppa, Deepika Pantham, Sara Sacchetti, Roberta Rolla, Margherita Grattarola, Chiara Monge, Stefania Pizzimenti, Umberto Dianzani, Chiara Dianzani, Luigi Battaglia
Publikováno v:
Pharmaceutics, Vol 15, Iss 3, p 937 (2023)
The most important limitations of chemotherapeutic agents are severe side effects and the development of multi-drug resistance. Recently, the clinical successes achieved with immunotherapy have revolutionized the treatment of several advanced-stage m
Externí odkaz:
https://doaj.org/article/75e773a78e284e2fb215421db80a3a54
Autor:
Chiara Monge, Ian Stoppa, Chiara Ferraris, Annalisa Bozza, Luigi Battaglia, Luigi Cangemi, Gianluca Miglio, Stefania Pizzimenti, Nausicaa Clemente, Casimiro Luca Gigliotti, Elena Boggio, Umberto Dianzani, Chiara Dianzani
Publikováno v:
Nanomaterials, Vol 12, Iss 23, p 4233 (2022)
High-grade melanoma remains a major life-threatening illness despite the improvement in therapeutic control that has been achieved by means of targeted therapies and immunotherapies in recent years. This work presents a preclinical-level test of a mu
Externí odkaz:
https://doaj.org/article/f1c2098e89e44523a47e692a13827ff3
Autor:
Chiara Puricelli, Elena Boggio, Casimiro Luca Gigliotti, Ian Stoppa, Salvatore Sutti, Roberta Rolla, Umberto Dianzani
Publikováno v:
Pharmaceutics, Vol 14, Iss 9, p 1782 (2022)
Conventional therapies for immune-mediated diseases, including autoimmune disorders, transplant reactions, and allergies, have undergone a radical evolution in the last few decades; however, they are still not specific enough to avoid widespread immu
Externí odkaz:
https://doaj.org/article/3e7a6caa267b46fb89a1fbbc258841ef
Autor:
Francesca Uberti, Vera Morsanuto, Silvio Aprile, Sabrina Ghirlanda, Ian Stoppa, Andrea Cochis, Giorgio Grosa, Lia Rimondini, Claudio Molinari
Publikováno v:
Journal of Ovarian Research, Vol 10, Iss 1, Pp 1-14 (2017)
Abstract Background Resveratrol (3,5,4′-trihydroxy-trans-stilbene) is a natural antioxidant polyphenol able to exert a wide range of biological effect on several tissues. Despite its important beneficial properties, it has a low water solubility, w
Externí odkaz:
https://doaj.org/article/d2dc70ef4ff844fc868eb95ace72860c