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pro vyhledávání: '"Ian S. Alexander"'
Publikováno v:
Biomedicines, Vol 10, Iss 3, p 655 (2022)
With the advent of cancer immunotherapy, there has been a major improvement in patient’s quality of life and survival. The growth of cancer immunotherapy has dramatically changed our understanding of the basics of cancer biology and has altered the
Externí odkaz:
https://doaj.org/article/6932c94d40064453b8e66d159588033a
Autor:
Chandra C. Ghosh, Kara R. Heatherton, Kyle P. O’ Connell, Ian S. Alexander, Deborah A. Greer, Jason LaPorte, Prajna Guha, Bryan F. Cox, Steven C. Katz
Publikováno v:
Cancer Gene Therapy. 29:1854-1865
Myeloid-derived suppressor cells (MDSCs) expand in response to malignancy and suppress responsiveness to immunotherapy, including checkpoint inhibitors (CPIs). Within the liver, MDSCs have unique immunosuppressive features. While TLR9 agonists have s