Zobrazeno 1 - 10
of 546
pro vyhledávání: '"Ian S Zagon"'
Publikováno v:
Medicine in Drug Discovery, Vol 11, Iss , Pp 100098- (2021)
Aims: Non-healing wounds are a major complication for the 27 million individuals in the United States with diagnosed diabetes. This study investigated the efficacy of a novel formulation to treat diabetic foot ulcers by targeting an underlying pathop
Externí odkaz:
https://doaj.org/article/4eae1014207340e2aa7a66b1c7457d6d
Publikováno v:
BMC Ophthalmology, Vol 19, Iss 1, Pp 1-8 (2019)
Abstract Background Dry eye disease (DED) is a prevalent complication of diabetes and presents as reduced tear production and/or increased corneal surface sensitivity often with secondary ocular surface changes. This study examined the safety and eff
Externí odkaz:
https://doaj.org/article/86b47628615f4e5fb7e8673d0ece813a
Publikováno v:
Journal of diabetes and clinical research. 4(1)
Diabetes is a chronic disorder that affects more than 500 million individuals worldwide. It is a life-long disease with complications that attack nearly all other systems within the body. Although there is a slight increase in the prevalence of diabe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::760361d5791efe94d0f131009e617280
https://pubmed.ncbi.nlm.nih.gov/36274979
https://pubmed.ncbi.nlm.nih.gov/36274979
Autor:
Patricia J. McLaughlin, Laura B. Odom, Peter A. Arnett, Shannon Orehek, Gary A. Thomas, Ian S. Zagon
Publikováno v:
International immunopharmacology. 113
Persons with multiple sclerosis (PwMS) have been considered at high risk for vaccination and/or acquisition of COVID-19 related to their reduced immune systems and daily regimen of immune suppressing therapy. Substantiated and unsubstantiated reports
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::48ca0f7310a6857e8faded340ad3e62e
https://pubmed.ncbi.nlm.nih.gov/36379151
https://pubmed.ncbi.nlm.nih.gov/36379151
Publikováno v:
Brain Research Bulletin. 165:246-252
Multiple sclerosis is a chronic progressive neurological disorder that has few distinctive biomarkers associated with disease progression or response to therapy. This research investigated whether non-invasive imaging correlated with animal behavior
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4c4c82dcdd7fa01a15eb333bccd7b5e8
https://doi.org/10.1016/j.brainresbull.2020.10.015
https://doi.org/10.1016/j.brainresbull.2020.10.015
Publikováno v:
Exp Biol Med (Maywood)
Diabetes often presents with ocular surface complications including dry eye, keratopathy, and altered sensitivity, along with systemic disorders. A common theme associated with corneal surface defects is decreased cellular proliferation. The opioid g
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d06be8ce257ee7a562660a792539de13
https://doi.org/10.1177/1535370220940273
https://doi.org/10.1177/1535370220940273
Publikováno v:
Journal of Diabetes Research, Vol 2016 (2016)
The Opioid Growth Regulatory System consists of opioid growth factor (OGF), [Met5]-enkephalin, and its unique receptor (OGFr). OGF inhibits cell division when bound to OGFr. Conversely, blockade of the interaction of OGF and OGFr, using the potent, l
Externí odkaz:
https://doaj.org/article/432178c11914426e986bc2436cc367d4
Autor:
Ian S. Zagon, Gregory S. Lewis, Patricia J. McLaughlin, Michelle B. Titunick, Jarrett D. Cain
Publikováno v:
Connective Tissue Research. 60:521-529
Purpose: This research investigated the presence and integrity of the opioid growth factor (OGF)—opioid growth factor receptor (OGFr) regulatory pathway in type 1 diabetic (T1D) rats, and i...
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cd7421cfee785ce4df2d93f6d574be8d
https://doi.org/10.1080/03008207.2019.1593396
https://doi.org/10.1080/03008207.2019.1593396
Publikováno v:
Experimental and Therapeutic Medicine
Approximately 4.5 million women in the United States exhibit diabetes-associated ocular complications. The time course and magnitude of these complications, and their association with the dysregulation of the opioid growth factor (OGF)-OGF receptor (
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::984f2b19eb9b6c045ac1a6dfced5fcb6
https://doi.org/10.3892/etm.2021.10119
https://doi.org/10.3892/etm.2021.10119
Publikováno v:
Multiple sclerosis and related disorders. 50
Multiple sclerosis (MS) is an autoimmune-mediated degenerative disorder with increased peripheral inflammation disrupting the blood brain barrier. With increasing MS-related healthcare costs, the requirement to validate minimally invasive biomarkers
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::58094694f7c2de9b55a41832d5aafe1a
https://pubmed.ncbi.nlm.nih.gov/33677409
https://pubmed.ncbi.nlm.nih.gov/33677409