Zobrazeno 1 - 10
of 85
pro vyhledávání: '"Ian S McLennan"'
Publikováno v:
PLoS ONE, Vol 11, Iss 9, p e0162509 (2016)
Circulating Anti-Müllerian hormone (AMH) is derived from the gonads, and is a mixture of the prohormone (proAMH), which does not bind to AMH receptors, and receptor-competent AMH. The functions of a hormone are partially defined by the factors that
Externí odkaz:
https://doaj.org/article/ba1c0d70801c42c3ad730baf9eacac50
Publikováno v:
PLoS ONE, Vol 10, Iss 7, p e0133637 (2015)
The testes secrete four hormones (anti-Müllerian hormone, insulin-like peptide 3, Inhibin B and testosterone) from two endocrine cell types. It is unknown whether anti-Müllerian hormone and insulin-like peptide 3 levels have a diurnal variation, an
Externí odkaz:
https://doaj.org/article/ee28cf1f3c4b424bba8f62606ecf9ce9
Autor:
Yih Harng Chong, Nicola A Dennis, Martin J Connolly, Ruth Teh, Gregory T Jones, Andre M van Rij, Stephanie Farrand, A John Campbell, Ian S McLennan
Publikováno v:
PLoS ONE, Vol 8, Iss 8, p e70967 (2013)
The Sertoli cells of the testes secrete anti-Müllerian hormone (Müllerian inhibiting Substance, AMH) and inhibin B (InhB). AMH triggers the degeneration of the uterine precursor in male embryos, whereas InhB is part of the gonadal-pituitary axis fo
Externí odkaz:
https://doaj.org/article/d310b45684214bbd92a3a13bb35fc842
Publikováno v:
PLoS ONE, Vol 8, Iss 3, p e58441 (2013)
Bone morphogenetic proteins (BMPs), members of the transforming growth factor-beta (TGF-β) superfamily, have been shown to play important roles in the nervous system, including neuronal survival and synaptogenesis. However, the physiological functio
Externí odkaz:
https://doaj.org/article/eab3057e9c034a008d83c90d6bce8e63
Publikováno v:
PLoS ONE, Vol 6, Iss 6, p e20533 (2011)
The testes of preadolescent boys appear to be dormant, as they produce only trace levels of testosterone. However, they release supra-adult levels of Müllerian Inhibiting Substance (MIS, anti-Müllerian hormone) and lesser levels of inhibin B (InhB)
Externí odkaz:
https://doaj.org/article/63f427c8ac03421a9893bb8fd9e2a169
Publikováno v:
Biology of Reproduction. 98:54-62
Anti-Mullerian hormone (AMH) is both a gonadal hormone and a putative paracrine regulator of neurons, the uterus, and the placenta. A mouse line with neuronal expression of AMH (Thy1.2-AMH) was generated to examine the role of paracrine AMH in the br
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dc059b5b8a139b2a7df05975b887cb40
https://doi.org/10.1093/biolre/iox151
https://doi.org/10.1093/biolre/iox151
Publikováno v:
Endocrine. 57:528-534
High levels of circulating anti-Mullerian hormone are unique to developing males, but the function of anti-Mullerian hormone in boys is unknown. In mice, anti-Mullerian hormone contributes to the male biases in the brain, but its receptors are presen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2bdd47422bbb58c800231f37a544273f
https://doi.org/10.1007/s12020-017-1333-2
https://doi.org/10.1007/s12020-017-1333-2
Publikováno v:
Molecular Reproduction and Development. 84:626-637
The hypothesis that, in contrast to other Transforming growth factor-beta (TGFβ) superfamily ligands, the dose-response curve of Anti-Mullerian hormone (AMH) is unmodulated was tested by examining whether known TGFB superfamily modulators affect AMH
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::df8b77643634ee5f3371c3c24ff7364b
https://doi.org/10.1002/mrd.22828
https://doi.org/10.1002/mrd.22828
Publikováno v:
Endocrinology. 157:1622-1629
Anti-Müllerian hormone (AMH) is a gonadal hormone that regulates aspects of male sexual differentiation and ovarian function. AMH is synthesized as the AMH proprotein precursor (proAMH), which is converted to a receptor-binding form (AMHN,C) by prot
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8e18897c81d51bd83dde3ebfb12803c4
https://doi.org/10.1210/en.2015-1834
https://doi.org/10.1210/en.2015-1834
Autor:
Michael W. Pankhurst, Ian S. McLennan
Publikováno v:
Molecular and Cellular Endocrinology. 419:165-171
The utility of serum anti-Müllerian hormone (AMH) assays in assessment of female fertility have been investigated extensively but little is known about the biological activity of the hormone being studied. ProAMH is the proprotein precursor and is i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::39ef0b63080050fdc1794d0a2222f2c2
https://doi.org/10.1016/j.mce.2015.10.013
https://doi.org/10.1016/j.mce.2015.10.013