Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Ian S D, Roberts"'
Autor:
Brian Shine, Robert Pell, Weiyu Ye, Mark R Middleton, Tim James, Stephanie Jones, Robert A Watson, Ian S D Roberts, Monika Hofer, Damian Jenkins, Miranda J Payne, Nicholas Coupe, Chelsea A Taylor, Elsita Jungkurth, Rosalin Cooper, Orion Tong, Eleni Ieremia, David Maldonado-Perez, Benjamin P Fairfax
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 12, Iss 4 (2024)
We describe three cases of critical acute myositis with myocarditis occurring within 22 days of each other at a single institution, all within 1 month of receiving the initial cycle of the anti-PD-1 drug pembrolizumab. Analysis of T cell receptor rep
Externí odkaz:
https://doaj.org/article/97a4f9e90ef947358cb17f5b1cd03194
Autor:
David L. Hölscher, Nassim Bouteldja, Mehdi Joodaki, Maria L. Russo, Yu-Chia Lan, Alireza Vafaei Sadr, Mingbo Cheng, Vladimir Tesar, Saskia V. Stillfried, Barbara M. Klinkhammer, Jonathan Barratt, Jürgen Floege, Ian S. D. Roberts, Rosanna Coppo, Ivan G. Costa, Roman D. Bülow, Peter Boor
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-14 (2023)
Pathology diagnostics still rely on tissue morphology assessment by trained experts. Here, the authors perform deep-learning-based segmentation followed by large-scale feature extraction of histological images, i.e., next-generation morphometry, to e
Externí odkaz:
https://doaj.org/article/23a6ad923ea34d429c8664558993fafc
Autor:
Janev Fehmi, Alexander J. Davies, Marilina Antonelou, Stephen Keddie, Sonja Pikkupeura, Luis Querol, Emilien Delmont, Andrea Cortese, Diego Franciotta, Staffan Persson, Jonathan Barratt, Ruth Pepper, Filipa Farinha, Anisur Rahman, Diana Canetti, Janet A. Gilbertson, Nigel B. Rendell, Aleksandar Radunovic, Thomas Minton, Geraint Fuller, Sinead M. Murphy, Aisling S. Carr, Mary R. Reilly, Filip Eftimov, Luuk Wieske, Charlotte E. Teunissen, Ian S. D. Roberts, Neil Ashman, Alan D. Salama, Simon Rinaldi
Publikováno v:
PLoS ONE, Vol 18, Iss 3 (2023)
Membranous glomerulonephritis (MGN) is a common cause of nephrotic syndrome in adults, mediated by glomerular antibody deposition to an increasing number of newly recognised antigens. Previous case reports have suggested an association between patien
Externí odkaz:
https://doaj.org/article/dff9589eb34c4a748b786c06b1069e74
Autor:
Richard Colling, Andrew Protheroe, Mark Sullivan, Ruth Macpherson, Mark Tuthill, Jacqueline Redgwell, Zoe Traill, Angus Molyneux, Elizabeth Johnson, Niveen Abdullah, Andrea Taibi, Nikki Mercer, Harry R. Haynes, Anthony Sackville, Judith Craft, Joao Reis, Gabrielle Rees, Maria Soares, Ian S. D. Roberts, Darrin Siiankoski, Helen Hemsworth, Derek Roskell, Sharon Roberts-Gant, Kieron White, Jens Rittscher, Jim Davies, Lisa Browning, Clare Verrill
Publikováno v:
Diagnostics, Vol 11, Iss 12, p 2191 (2021)
Background: In this article we share our experience of creating a digital pathology (DP) supraregional germ cell tumour service, including full digitisation of the central laboratory. Methods: DP infrastructure (Philips) was deployed across our hospi
Externí odkaz:
https://doaj.org/article/3ca0341550b64a49b16959b7daed5916
Autor:
Mehdi Joodaki, Mina Shaigan, Victor Parra, Roman D. Buelow, Christoph Kuppe, David L. Holscher, Mingbo Cheng, James S. Nagai, Nassim Bouteldja, Vladimir Tesar, Jonathan Barratt, Ian S. D. Roberts, Rosanna Coppo, Rafael Kramann, Peter Boor, Ivan G. Costa
Publikováno v:
Cold Spring Harbor : Cold Spring Harbor Laboratory, bioRxiv : the preprint server for biology [1]-24 (2022). doi:10.1101/2022.12.16.520739
Although clinical applications represent the next challenge in single-cell genomics and digital pathology, we still lack computational methods to analyze single-cell and pathomics data to find sample level trajectories or clusters associated with dis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::72b38dcefde29a560a55153f98a14383
https://publications.rwth-aachen.de/record/862383
https://publications.rwth-aachen.de/record/862383
Autor:
Robert Pell, S Kim Suvarna, Nigel Cooper, Guy Rutty, Anna Green, Michael Osborn, Peter Johnson, Alison Hayward, Justine Durno, Theodore Estrin-Serlui, Marion Mafham, Ian S D Roberts
Publikováno v:
Journal of Clinical Pathology
AimsWidespread disruption of healthcare services and excess mortality not directly attributed to COVID-19 occurred between March and May 2020. We undertook the first UK multicentre study of coroners’ autopsies before and during this period using po
Autor:
Sharon Ashworth, Beina Teng, Jessica Kaufeld, Emily Miller, Irini Tossidou, Christoph Englert, Frank Bollig, Lynne Staggs, Ian S D Roberts, Joon-Keun Park, Hermann Haller, Mario Schiffer
Publikováno v:
PLoS ONE, Vol 5, Iss 9, p e12626 (2010)
BACKGROUND: Podocytes are highly specialized epithelial cells on the visceral side of the glomerulus. Their interdigitating primary and secondary foot processes contain an actin based contractile apparatus that can adjust to changes in the glomerular
Externí odkaz:
https://doaj.org/article/1d197e41d627485087b1d5bdf9a70c5d
Autor:
Maria F, Soares, Vera, Genitsch, Aron, Chakera, Andrew, Smith, Clare, MacEwen, Shubha S, Bellur, Nasullah K, Alham, Ian S D, Roberts
Publikováno v:
Histopathology. 74(4)
The Oxford Classification E score (endocapillary hypercellularity) predicts renal functional decline in IgA nephropathy (IgAN) patients free from steroid/immunosuppressive (IS) therapy, but is poorly reproducible. We hypothesise that endocapillary hy
Autor:
Ian S D, Roberts
Publikováno v:
Transactions of the Medical Society of London. 129
Autor:
Tamara Mallett, Jan Dudley, Jane Tizard, Judit Sutak, Ian S D Roberts, Moin A Saleem, Martin Mraz
Publikováno v:
Research. 1