Zobrazeno 1 - 10
of 41
pro vyhledávání: '"Ian R. Logan"'
Publikováno v:
Nucleic Acids Research. 49:10203-10206
Autor:
Ian R. Logan, Alison L. Brown
Publikováno v:
Cogent Medicine, Vol 4, Iss 1 (2017)
Near drowning is an important, but rarely reported precipitant of acute kidney injury (AKI). The underlying pathophysiology is thought to be ischaemic kidney injury, but diagnostic uncertainty has arisen due to reports of isolated AKI in the absence
Externí odkaz:
https://doaj.org/article/6f376c6438944d7faf5bb1025ca2bfde
Publikováno v:
Hypertension. 76:859-865
Investigation for secondary causes is recommended in early onset hypertension. However, obesity is associated with higher blood pressure (BP), so investigation for alternative secondary causes may not be necessary in all obese patients. We sought to
Autor:
Aghogho Odudu, Jamie Willows, Ian R. Logan, Neil S. Sheerin, Timothy Ellam, Charles R.V. Tomson
Publikováno v:
American journal of nephrology. 50(2)
Background: If loss of functioning nephrons predisposes to glomerular barotrauma (a “remnant nephron” effect), then glomerular permeability should increase as glomerular filtration rate (GFR) falls, as is observed in animal models of nephron loss
Autor:
Ian R. Logan, Charles R.V. Tomson
Publikováno v:
British Journal of Hospital Medicine. 77:639-644
Hypertension is a common clinical problem in patients with chronic kidney disease. This article should equip the non-specialty doctor with the general principles pertaining to the investigation and treatment of hypertension in these patients. It also
Publikováno v:
BMJ. :m24
What you need to know In many countries (including the UK and Australia) it is still common practice for hospital doctors to write letters to patients’ general practitioners (GPs) following outpatient consultations, and for patients to receive copi
Autor:
Caitlin A. Mooney, Victoria G. Shuttleworth, Ian R. Logan, Lotfia S Nawafa, Steven L. Cobb, Luke Gaughan, Neil S. Sheerin
Publikováno v:
Journal of Cell Science.
Chronic kidney disease (CKD) is a global socioeconomic problem. It is characterised by the presence of differentiated myofibroblasts that, in response to TGF B-1, produce tissue fibrosis, leading to renal failure. Here we define a novel interaction b
Autor:
John R. Kirby, Simi Ali, Anna Moles, Neil S. Sheerin, Gerhard Reinaldi Situmorang, Ian R. Logan, Akmal Taher
Publikováno v:
Nephrology Dialysis Transplantation. 32:iii80-iii81
Autor:
Frances V. Fuller-Pace, John Lunec, Hesta V. McNeill, David W. Meek, Craig N. Robson, Ian R. Logan, Xiaohong Lu, Susan Cook
Publikováno v:
Nucleic Acids Research
Here we define an important role for heat shock factor 1 (HSF1) in the cellular response to genotoxic agents. We demonstrate for the first time that HSF1 can complex with nuclear p53 and that both proteins are co-operatively recruited to p53-responsi
Publikováno v:
The International Journal of Biochemistry & Cell Biology. 40:236-244
Tat-interactive protein 60 kDa is a nuclear acetyltransferase that both coactivates and corepresses transcription factors and has a definitive function in the DNA damage response. Here, we provide evidence that Tat-interactive protein 60 kDa is phosp