Výsledky vyhledávání - "Ian R. Judson"

Akademický článek

Noninvasive Magnetic Resonance Spectroscopic Pharmacodynamic Markers of a Novel Histone Deacetylase Inhibitor, LAQ824, in Human Colon Carcinoma Cells and Xenografts

Autor: Yuen-Li Chung, Helen Troy, Rebecca Kristeleit, Wynne Aherne, L. Elizabeth Jackson, Peter Atadja, John R. Griffiths, Ian R. Judson, Paul Workman, Martin O. Leach, Mounia Beloueche-Babari

Publikováno v: Neoplasia: An International Journal for Oncology Research, Vol 10, Iss 4, Pp 303-313 (2008)

The aim of this work was to use phosphorus magnetic resonance spectroscopy (31P MRS) to investigate the pharmacodynamic effects of LAQ824, a histone deacetylase (HDAC) inhibitor. Human HT29 colon carcinoma cells were examined by 31P MRS after treatme

Externí odkaz: https://doaj.org/article/fe40d0898e264b54a206180207b9790f

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Akademický článek

A Case of Ovarian Fibromatosis and Massive Ovarian Oedema Associated With Intra-Abdominal Fibromatosis, Sclerosing Peritonitis and Meig’s Syndrome

Autor: Emma L. Spurrell, Yen C. Yeo, Terence P. Rollason, Ian R. Judson

Publikováno v: Sarcoma, Vol 8, Iss 4, Pp 113-121 (2004)

Purpose:To discuss a case of ovarian fibromatosis/massive ovarian oedema, intra-abdominal fibromatosis, sclerosing peritonitis and Meig’s syndrome. To review the reported therapeutic options.

Externí odkaz: https://doaj.org/article/7ce0e276f9894fdc86e5b10cc8d983b3

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Akademický článek

Susceptibility of Fibromatosis Cells in Short-Term Culture to Ifosfamide: A Possible Experimental Treatment in Clinically Aggressive Cases

Autor: Mark W. Verrill, Helen M. Coley, Ian R. Judson, Cyril Fisher

Publikováno v: Sarcoma, Vol 3, Iss 2, Pp 79-84 (1999)

Purpose. Deep fibromatoses are large, often rapidly growing but benign soft tissue tumours. Although surgery is the mainstay of treatment, in unremitting and aggressive cases the use of cytotoxic chemotherapy may produce objective tumour responses

Externí odkaz: https://doaj.org/article/9c2ec041e2ab464b908c1fefed4b23cb

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Akademický článek

A Phase I/II Study of a 72-h Continuous Infusion of Etoposide in Advanced Soft Tissue Sarcoma

Autor: Charles R. Crawley, Ian R. Judson, Mark Verrill, Catherine Hill, Florence I. Raynaud

Publikováno v: Sarcoma, Vol 1, Iss 3-4, Pp 149-154 (1997)

Purpose. The study was performed to assess the antitumour activity and toxicity of a 72-h continuous infusion of single-agent etoposide as second-line treatment for patients with locally advanced or metastatic soft tissue sarcoma (STS), following rep

Externí odkaz: https://doaj.org/article/0ef2cd0f6ead41d8bf46653e7af92f3f

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Akademický článek

Targeting the Insulin-Like Growth Factor 1 Receptor in Ewing's Sarcoma: Reality and Expectations

Autor: David Olmos, Ana Sofia Martins, Robin L. Jones, Salma Alam, Michelle Scurr, Ian R. Judson

Publikováno v: Sarcoma, Vol 2011 (2011)

Ewing's sarcoma family of tumours comprises a group of very aggressive diseases that are potentially curable with multimodality treatment. Despite the undoubted success of current treatment, approximately 30% of patients will relapse and ultimately d

Externí odkaz: https://doaj.org/article/524cb604f6e949f984d6ff0dafe4fe6a

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Akademický článek

Clinical Benefit of Second-Line Palliative Chemotherapy in Advanced Soft-Tissue Sarcoma

Autor: Anna Minchom, Robin L. Jones, Cyril Fisher, Omar Al-Muderis, Sue Ashley, Michelle Scurr, Vasilios Karavasilis, Ian R. Judson

Publikováno v: Sarcoma, Vol 2010 (2010)

Background. This paper aimed to assess the utility of second-line chemotherapy in patients with advanced soft-tissue sarcoma. Materials and Methods. A retrospective search of a prospectively maintained database identified patients treated between 199

Externí odkaz: https://doaj.org/article/785ba3f3ae464d03b8bfb1fd4a822458

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