Zobrazeno 1 - 10
of 52
pro vyhledávání: '"Ian R. Doyle"'
Publikováno v:
Journal of Forensic and Legal Medicine. 15:48-52
OBJECTIVE: To describe the changes in lung-specific secretory proteins in biological fluids in a fatal case of paraquat ingestion and to present immunostaining data obtained on postmortem lung tissue specimens. METHODS: A 20-year-old man committed su
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::331e62c293975a96dea24af721a63e4a
https://doi.org/10.1016/j.jcfm.2006.09.003
https://doi.org/10.1016/j.jcfm.2006.09.003
Autor:
PE Aylward, Leonard F Arnolda, Ian R. Doyle, A. E. Russell, Carmine G. De Pasquale, Andrew D. Bersten
Publikováno v:
Clinical and Experimental Pharmacology and Physiology. 32:622-627
SUMMARY 1. As a result of its enormous surface area and necessary thinness for gas exchange, the alveolocapillary barrier is vulnerable to mechanical disruption from raised pulmonary microvascular pressure (Pmv). 2. Because surfactant protein-B (SP-B
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::449fa539b5ac229227fde2635582670c
https://doi.org/10.1111/j.0305-1870.2005.04241.x
https://doi.org/10.1111/j.0305-1870.2005.04241.x
Publikováno v:
American Journal of Physiology-Lung Cellular and Molecular Physiology. 289:L96-L103
Alveolar macrophages (AM) may be exposed to a range of CO2and pH levels depending on their location in the alveoli and the health of the lung. Cytokines produced by AM contribute to inflammation in acute lung injury (ALI). Current ventilatory practic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e84184258a0176e41115e1235d83bc3a
https://doi.org/10.1152/ajplung.00394.2004
https://doi.org/10.1152/ajplung.00394.2004
Autor:
Ian R. Doyle, Carmine G. De Pasquale, Leonard F Arnolda, Philip E. Aylward, Derek P. Chew, Andrew D. Bersten
Publikováno v:
Circulation. 110:1091-1096
Background— In chronic heart failure (CHF), elevated pulmonary microvascular pressure (P mv ) results in pulmonary edema. Because elevated P mv may alter the integrity of the alveolocapillary barrier, allowing leakage of surfactant protein-B (SP-B)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bf933d8b77bcc8d2d275c70e45c3ce68
https://doi.org/10.1161/01.cir.0000140260.73611.fa
https://doi.org/10.1161/01.cir.0000140260.73611.fa
Publikováno v:
American Journal of Physiology-Heart and Circulatory Physiology. 284:H2136-H2145
Chronic heart failure (CHF) is associated with adaptive structural changes at the alveolocapillary barrier that may be associated with altered protein permeability. Bidirectional protein movement across the barrier was studied in anesthetized rats wi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2b51648614ae99a3bac51afb1c9335f3
https://doi.org/10.1152/ajpheart.00875.2002
https://doi.org/10.1152/ajpheart.00875.2002
Autor:
J-P Buchet, Olivier Michel, Ian R. Doyle, C. de Burbure, Xavier Dumont, Sylviane Carbonnelle, Cédric Hermans, S Higuet, Alfred Bernard
Publikováno v:
Occupational and environmental medicine, Vol. 60, no. 6, p. 385-394 (2003)
AIMS: To study whether exposure to nitrogen trichloride in indoor chlorinated pools may affect the respiratory epithelium of children and increase the risk of some lung diseases such as asthma. METHODS: In 226 healthy children, serum surfactant assoc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6fd0dbff365fedc511d4e3424568c50b
https://doi.org/10.1136/oem.60.6.385
https://doi.org/10.1136/oem.60.6.385
Autor:
Ian R. Doyle, Richard I. Fisher, Otto D. Schoch, Ashley R. Dunn, K Uchida, Emi Hamano, Jeffrey J. Presneill, John F. Seymour, Koh Nakata
Publikováno v:
Thorax. 58:252-257
Background: Conventional measures of the severity of alveolar proteinosis (AP) include alveolar-arterial oxygen gradient ([A – a]Do 2 ), vital capacity (VC), and carbon monoxide transfer factor (Tlco), but alternative serological measures have been
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ce95e496509257b5d593d67bcd1a6158
https://doi.org/10.1136/thorax.58.3.252
https://doi.org/10.1136/thorax.58.3.252
Publikováno v:
European Respiratory Journal. 20:1152-1161
Since the 16-kDa bronchiolar Clara cell protein (CC16) and the alveolar surfactant-associated proteins (SP)-A and -B leak into the circulation when parenchymal health is disturbed, the aim of this study was to determine whether their serum levels cou
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f1c00027f7c76c2139c795dbe7f931f1
https://doi.org/10.1183/09031936.02.02042001
https://doi.org/10.1183/09031936.02.02042001
Autor:
Ian R. Doyle, Koh Nakata, Gordon H. Downie, Jeffrey J. Presneill, Takayuki Kitamura, David Langton, John F. Seymour, Ashley R. Dunn, Paul E. Moore, Otto D. Schoch, Janette M. Vincent, Michael C. Pain
Publikováno v:
American Journal of Respiratory and Critical Care Medicine, 163(2), 524-531. AMER THORACIC SOC
Alveolar proteinosis (AP) is characterized by excessive surfactant accumulation, and most cases are of unknown etiology. Standard therapy for AP is whole-lung lavage, which may not correct the underlying defect. Because the hematopoietic cytokine gra
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e9619659a99219713ade52d3f6435c27
https://doi.org/10.1164/ajrccm.163.2.2003146
https://doi.org/10.1164/ajrccm.163.2.2003146
Autor:
Ian R. Doyle, Heather A. Barr, Kate G. Davidson, Terence E. Nicholas, Andrew D. Bersten, Kay D. Dowling
Publikováno v:
American Journal of Physiology-Lung Cellular and Molecular Physiology. 279:L1091-L1102
Although acute lung injury (ALI) is associated with inflammation and surfactant dysfunction, the precise sequence of these changes remains poorly described. We used oleic acid to study the pathogenesis of ALI in spontaneously breathing anesthetized r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::63079b61e8bf4bd94afbd2f1be92d132
https://doi.org/10.1152/ajplung.2000.279.6.l1091
https://doi.org/10.1152/ajplung.2000.279.6.l1091