Zobrazeno 1 - 10
of 27
pro vyhledávání: '"Ian R. D. Johnson"'
Autor:
Jessica M. Logan, Carmela Martini, Alexandra Sorvina, Ian R. D. Johnson, Robert D. Brooks, Maria C. Caruso, Chelsea Huzzell, Courtney R. Moore, Litsa Karageorgos, Lisa M. Butler, Prerna Tewari, Sarita Prabhakaran, Shane M. Hickey, Sonja Klebe, Hemamali Samaratunga, Brett Delahunt, Kim Moretti, John J. O’Leary, Douglas A. Brooks, Ben S.-Y. Ung
Publikováno v:
Scientific Data, Vol 11, Iss 1, Pp 1-10 (2024)
Abstract The diagnosis of prostate cancer using histopathology is reliant on the accurate interpretation of prostate tissue sections. Current standards rely on the assessment of Haematoxylin and Eosin (H&E) staining, which can be difficult to interpr
Externí odkaz:
https://doaj.org/article/7812ab7abe164dde80c9cc732a6b3935
Autor:
Weranga Rajapaksha, Riya Khetan, Ian R. D. Johnson, Anton Blencowe, Sanjay Garg, Hugo Albrecht, Todd A. Gillam
Publikováno v:
Frontiers in Drug Delivery, Vol 4 (2024)
Ovarian cancers are a complex and heterogenic group of malignancies that are difficult to detect, diagnose and treat. Fortunately, considerable knowledge of ovarian cancer specific biomarkers has been generated, that is pertinent to the development o
Externí odkaz:
https://doaj.org/article/b4513d829c8b43c4a35196f93caa174d
Autor:
Joanna Lazniewska, Ka Lok Li, Ian R. D. Johnson, Alexandra Sorvina, Jessica M. Logan, Carmela Martini, Courtney Moore, Ben S.-Y. Ung, Litsa Karageorgos, Shane M. Hickey, Sarita Prabhakaran, Jessica K. Heatlie, Robert D. Brooks, Chelsea Huzzell, Nicholas I. Warnock, Mark P. Ward, Bashir Mohammed, Prerna Tewari, Cara Martin, Sharon O’Toole, Laura Bogue Edgerton, Mark Bates, Paul Moretti, Stuart M. Pitson, Stavros Selemidis, Lisa M. Butler, John J. O’Leary, Douglas A. Brooks
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-18 (2023)
Abstract Prostate cancer (PCa) development and progression relies on the programming of glucose and lipid metabolism, and this involves alterations in androgen receptor expression and signalling. Defining the molecular mechanism that underpins this m
Externí odkaz:
https://doaj.org/article/50253ef611194e4595e03d647adf9305
Fluid and Bubble Flow Detach Adherent Cancer Cells to Form Spheroids on a Random Positioning Machine
Autor:
José Luis Cortés-Sánchez, Daniela Melnik, Viviann Sandt, Stefan Kahlert, Shannon Marchal, Ian R. D. Johnson, Marco Calvaruso, Christian Liemersdorf, Simon L. Wuest, Daniela Grimm, Marcus Krüger
Publikováno v:
Cells, Vol 12, Iss 22, p 2665 (2023)
In preparing space and microgravity experiments, the utilization of ground-based facilities is common for initial experiments and feasibility studies. One approach to simulating microgravity conditions on Earth is to employ a random positioning machi
Externí odkaz:
https://doaj.org/article/0f32450df8c24fc0ae9d647013e8627a
Autor:
Giang T. Lam, Carmela Martini, Tiffany Brooks, Sarita Prabhakaran, Ashley M. Hopkins, Ben S.-Y. Ung, Jingying Tang, Maria C. Caruso, Robert D. Brooks, Ian R. D. Johnson, Alexandra Sorvina, Shane M. Hickey, Litsa Karageorgos, Sonja Klebe, John J. O’Leary, Douglas A. Brooks, Jessica M. Logan
Publikováno v:
Cancers, Vol 15, Iss 18, p 4631 (2023)
Background: Early diagnosis is the key to improving outcomes for patients with melanoma, and this requires a standardized histological assessment approach. The objective of this survey was to understand the challenges faced by clinicians when assessi
Externí odkaz:
https://doaj.org/article/475ab1b1abb04cf9808d410a11f7f1c1
Autor:
Jessica M. Logan, Ashley M. Hopkins, Carmela Martini, Alexandra Sorvina, Prerna Tewari, Sarita Prabhakaran, Chelsea Huzzell, Ian R. D. Johnson, Shane M. Hickey, Ben S.-Y. Ung, Joanna Lazniewska, Robert D. Brooks, Courtney R. Moore, Maria C. Caruso, Litsa Karageorgos, Cara M. Martin, Sharon O’Toole, Laura Bogue Edgerton, Mark P. Ward, Mark Bates, Stavros Selemidis, Adrian Esterman, Sheena Heffernan, Helen Keegan, Sarah Ní Mhaolcatha, Roisin O’Connor, Victoria Malone, Marguerite Carter, Katie Ryan, Andres Clarke, Nathan Brady, Sonja Klebe, Hemamali Samaratunga, Brett Delahunt, Michael J. Sorich, Kim Moretti, Lisa M. Butler, John J. O’Leary, Douglas A. Brooks
Publikováno v:
Cancers, Vol 15, Iss 12, p 3215 (2023)
Gleason scoring is used within a five-tier risk stratification system to guide therapeutic decisions for patients with prostate cancer. This study aimed to compare the predictive performance of routine H&E or biomarker-assisted ISUP (International So
Externí odkaz:
https://doaj.org/article/b0042daff2db49f98a2094ebe85cdd67
Autor:
Shane M. Hickey, Ben Ung, Christie Bader, Robert Brooks, Joanna Lazniewska, Ian R. D. Johnson, Alexandra Sorvina, Jessica Logan, Carmela Martini, Courtney R. Moore, Litsa Karageorgos, Martin J. Sweetman, Douglas A. Brooks
Publikováno v:
Cells, Vol 11, Iss 1, p 35 (2021)
Fluorescence microscopy has become a critical tool for researchers to understand biological processes at the cellular level. Micrographs from fixed and live-cell imaging procedures feature in a plethora of scientific articles for the field of cell bi
Externí odkaz:
https://doaj.org/article/26b29595c70c47f8a2ea463c7848b882
Publikováno v:
International Journal of Molecular Sciences, Vol 21, Iss 21, p 8205 (2020)
Space exploration poses multiple challenges for mankind, not only on a technical level but also to the entire physiology of the space traveller. The human system must adapt to several environmental stressors, microgravity being one of them. Lysosomes
Externí odkaz:
https://doaj.org/article/7fc3853a540a4d6ba269d92ac5e9635a
Autor:
Giang T. Lam, Sarita Prabhakaran, Alexandra Sorvina, Carmela Martini, Ben S.-Y. Ung, Litsa Karageorgos, Shane M. Hickey, Joanna Lazniewska, Ian R. D. Johnson, Desmond B. Williams, Sonja Klebe, Victoria Malone, John J. O’Leary, Louise Jackett, Doug A. Brooks, Jessica M. Logan
Publikováno v:
Molecular Diagnosis & Therapy. 27:49-60
Refereed/Peer-reviewed Cutaneous melanoma is one of the most aggressive forms of skin cancer, with the development of advanced stage disease resulting in a high rate of patient mortality. Accurate diagnosis of melanoma at an early stage is essential
Autor:
Zhiguo Yuan, Philip L. Bond, Xuan Li, Ian R D Johnson, Lucija Hanzic, Simeon Wilkie, Guangming Jiang, Liza O'Moore, Kara Mueller
Publikováno v:
The Science of the total environment. 806(Pt 3)
Microbially influenced concrete corrosion (MICC) in sewers is caused by the activity of sulfide-oxidizing microorganisms (SOMs) on concrete surfaces, which greatly deteriorates the integrity of sewers. Surface treatment of corroded concrete by sprayi