Zobrazeno 1 - 10
of 75
pro vyhledávání: '"Ian R Wickersham"'
Autor:
Connor M Wander, Ya-Dong Li, Hechen Bao, Brent Asrican, Yan-Jia Luo, Heather A Sullivan, Tzu-Hao Harry Chao, Wei-Ting Zhang, Samantha L Chéry, Dalton S Tart, Ze-Ka Chen, Yen-Yu Ian Shih, Ian R Wickersham, Todd J Cohen, Juan Song
Publikováno v:
Journal of Translational Medicine, Vol 21, Iss 1, Pp 1-17 (2023)
Abstract Background Alzheimer’s disease (AD) is characterized by a progressive loss of memory that cannot be efficiently managed by currently available AD therapeutics. So far, most treatments for AD that have the potential to improve memory target
Externí odkaz:
https://doaj.org/article/b86bc6cf52144cdf81b7f50dbae489f8
Publikováno v:
Frontiers in Neural Circuits, Vol 2 (2007)
A recombinant rabies virus was used as a retrograde tracer to allow complete fi lling of the axonal and dendritic arbors of identifi ed projection neurons in layer 5 of mouse primary somatosensory cortex (S1) in vivo. Previous studies have distinguis
Externí odkaz:
https://doaj.org/article/7f28afaa2fbd4c54a8070e63aea2a2dc
Autor:
Aixin Zhang, Lei Jin, Shenqin Yao, Makoto Matsuyama, Cindy van Velthoven, Heather Sullivan, Na Sun, Manolis Kellis, Bosiljka Tasic, Ian R. Wickersham, Xiaoyin Chen
Publikováno v:
bioRxiv
Mapping the connectivity of diverse neuronal types provides the foundation for understanding the structure and function of neural circuits. High-throughput and low-cost neuroanatomical techniques based on RNA barcode sequencing have the potential to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::47f736d338c03cc031e638b3c328e4a4
https://doi.org/10.1101/2023.03.16.532873
https://doi.org/10.1101/2023.03.16.532873
Autor:
Mulangma Zhu, María Lucía Dam Ferdínez, Heather A. Sullivan, Thomas K. Lavin, Lei Jin, Nicholas E. Lea, YuanYuan Hou, Maxwell T. Pruner, Makoto Matsuyama, Ian R. Wickersham
Publikováno v:
Proceedings of the National Academy of Sciences. 120
Monosynaptic tracing using rabies virus is an important technique in neuroscience, allowing brain- wide labeling of neurons directly presynaptic to a targeted neuronal population. A 2017 article reported development of a noncytotoxic version – a ma
Autor:
Yi Ning Leow, Blake Zhou, Heather A. Sullivan, Alexandria R. Barlowe, Ian R. Wickersham, Mriganka Sur
Publikováno v:
Journal of Comparative Neurology. 530:1992-2013
The rodent homolog of the primate pulvinar, the lateral posterior (LP) thalamus, is extensively interconnected with multiple cortical areas. While these cortical interactions can span the entire LP, subdivisions of the LP are characterized by differe
Autor:
Ian R. Wickersham, Nora L. Benavidez, Jun-Hyeok Choi, Jim Stanis, Tao Jiang, Yasmine Sherafat, Marlene Becerra, Amanda J. Tugangui, Lin Gou, Hong-Wei Dong, Byung Kook Lim, Hui Gong, Nicholas N. Foster, Xiangning Li, Hyun-Seung Mun, Zhao Feng, Ian Bowman, Anthony Santarelli, Joshua Barry, Luis Garcia, Lei Gao, Muye Zhu, Gordon Dan, Qingming Luo, Brian Zingg, Tyler Boesen, David L. Johnson, Sarvia Aquino, Marina Fayzullina, Darrick Lo, Neda Khanjani, Joel D. Hahn, Bo Peng, X. William Yang, Monica Song, Carlos Cepeda, Anan Li, Sarah Ustrell, Michael S. Bienkowski, Chunru Cao, Seita Yamashita, Houri Hintiryan, Sana Azam, Xueyan Jia, Hanpeng Xu, Bin Zhang, Michael Levine, Li I. Zhang, Kaelan Cotter, Laura Korobkova
Publikováno v:
Nature
The cortico–basal ganglia–thalamo–cortical loop is one of the fundamental network motifs in the brain. Revealing its structural and functional organization is critical to understanding cognition, sensorimotor behaviour, and the natural history
Autor:
Cuiyu Xiao, Jinxing Wei, Guang-wei Zhang, Can Tao, Junxiang J. Huang, Li Shen, Ian R. Wickersham, Huizhong W. Tao, Li I. Zhang
Publikováno v:
Neuron. 111:1486-1503.e7
Autor:
Ying Zhang, Dheeraj S. Roy, Yi Zhu, Yefei Chen, Tomomi Aida, Yuanyuan Hou, Chenjie Shen, Nicholas E. Lea, Margaret E. Schroeder, Keith M. Skaggs, Heather A. Sullivan, Kyle B. Fischer, Edward M. Callaway, Ian R. Wickersham, Ji Dai, Xiao-Ming Li, Zhonghua Lu, Guoping Feng
Publikováno v:
Nature
Although bradykinesia, tremor, and rigidity are the hallmark motor defects in Parkinson’s disease (PD) patients, they also experience motor learning impairments and non-motor symptoms such as depression(1). The neural circuit basis for these differ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a045ec54d2bef435e0515273dbc4cd9f
https://europepmc.org/articles/PMC9403858/
https://europepmc.org/articles/PMC9403858/
Autor:
K. Guadalupe Cruz, Gerald N. Pho, Mriganka Sur, Liadan M. Gunter, Rafiq Huda, Austin Sullins, Grayson O. Sipe, Elie M. Adam, Vincent Breton-Provencher, Ian R. Wickersham
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-17 (2020)
Nature Communications
Nature Communications
Sensorimotor behaviors require processing of behaviorally relevant sensory cues and the ability to select appropriate responses from a vast behavioral repertoire. Modulation by the prefrontal cortex (PFC) is thought to be key for both processes, but
Autor:
Lei Jin, Heather A. Sullivan, Mulangma Zhu, Nicholas E. Lea, Thomas K. Lavin, Makoto Matsuyama, YuanYuan Hou, Ian R. Wickersham
SUMMARYRabies viral vectors have become important components of the systems neuroscience toolkit, allowing both direct retrograde targeting of projection neurons and monosynaptic tracing of inputs to defined postsynaptic populations, but the rapid cy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d17277edf2cd9b2b123930695516ee8c
https://doi.org/10.1101/2022.02.23.481706
https://doi.org/10.1101/2022.02.23.481706