Zobrazeno 1 - 10
of 61
pro vyhledávání: '"Ian R Duce"'
Autor:
Himanshu Kharkwal, Farhat Batool, Frank Koentgen, David R Bell, David A Kendall, Francis J P Ebling, Ian R Duce
Publikováno v:
PLoS ONE, Vol 12, Iss 12, p e0187959 (2017)
Cytochrome P450 4x1 (Cyp4x1) is expressed at very high levels in the brain but the function of this protein is unknown. It has been hypothesised to regulate metabolism of fatty acids and to affect the activity of endocannabinoid signalling systems, w
Externí odkaz:
https://doaj.org/article/a951ee8c28ec47a3ba7837f898eaae29
Publikováno v:
Parasites & Vectors, Vol 7, Iss 1, Pp 1-8 (2014)
Abstract Background Cysteine proteinases (CPs) from papaya (Carica papaya) possess anthelmintic properties against human soil-transmitted helminths (STH, Ascaris lumbricoides, Trichuris trichiura and hookworm), but there is a lack of supportive and u
Externí odkaz:
https://doaj.org/article/f876ae05b8ae414f8519fe5731b85c6f
Autor:
David P. Richards, Rohit N. Patel, Ian R. Duce, Bhupinder P. S. Khambay, Michael A. Birkett, John A. Pickett, Ian R. Mellor
Publikováno v:
Molecules, Vol 27, Iss 20, p 7074 (2022)
Ladybird beetles (Coleoptera: Coccinellidae) possess strong chemical defences that are secreted in response to stress and are also found on the coating of eggs, which are rich in alkaloids that are responsible for their toxicity to other species. Rec
Externí odkaz:
https://doaj.org/article/a1d8a3d609e74298b42062a3f07ec78d
Autor:
Neville M. Ngum, Muhammad Y. A. Aziz, Liaque Mohammed Latif, Richard J. Wall, Ian R. Duce, Ian R. Mellor
Publikováno v:
The Journal of Physiology. 600:2499-2513
Autor:
David P, Richards, Rohit N, Patel, Ian R, Duce, Bhupinder P S, Khambay, Michael A, Birkett, John A, Pickett, Ian R, Mellor
Publikováno v:
Molecules (Basel, Switzerland). 27(20)
Ladybird beetles (Coleoptera: Coccinellidae) possess strong chemical defences that are secreted in response to stress and are also found on the coating of eggs, which are rich in alkaloids that are responsible for their toxicity to other species. Rec
Autor:
Jerzy M. Behnke, Iain L. Johnstone, Oumu Diallo, Tim Winks, Ann Lowe, Ian R. Duce, Victor S. Njom, David J. Buttle, Mark J. Dickman
Publikováno v:
Parasites & Vectors, Vol 14, Iss 1, Pp 1-11 (2021)
Parasites & Vectors
Parasites & Vectors
Background Plant-derived cysteine proteinases of the papain family (CPs) attack nematodes by digesting the cuticle, leading to rupture and death of the worm. The nematode cuticle is composed of collagens and cuticlins, but the specific molecular targ
Publikováno v:
Heliyon, Vol 7, Iss 10, Pp e08125-(2021)
Heliyon
Heliyon
Plant derived cysteine proteinases (CPs) have long been known to possess anthelmintic properties but have attracted renewed attention recently because of the acute need to discover novel methods for controlling helminth infections as a result of incr
Autor:
Ian R. Duce, T.G. Emyr Davies, Martin S. Williamson, Ian R. Mellor, Mark J. Burton, Linda M. Field, Paul S. Verdin, Andrew J. Thompson, Richard A. Baines
Publikováno v:
Insect Biochemistry and Molecular Biology. 122:103388
Voltage-gated sodium channels (VGSCs) are a major target site for the action of pyrethroid insecticides and resistance to pyrethroids has been ascribed to mutations in the VGSC gene. VGSCs in insects are encoded by only one gene and their structural
Autor:
David Richards, Ian R. Duce, Rohit N. Patel, Michael A. Birkett, David B. Sattelle, Ian R. Mellor
Publikováno v:
Pesticide Biochemistry and Physiology. 166:104561
© 2020 Elsevier Inc. The harlequin ladybird, Harmonia axyridis (H. axyridis), possesses a strong chemical defence that has contributed to its invasive success. Ladybird beetle defensive chemicals, secreted in response to stress and also found on the
Publikováno v:
Parasitology Research. 114:2535-2541
The development of plant-derived cysteine proteinases, such as those in papaya latex, as novel anthelmintics requires that the variables affecting efficacy be fully evaluated. Here, we conducted two experiments, the first to test for any effect of ho