Zobrazeno 1 - 10
of 42
pro vyhledávání: '"Ian Pitha"'
Autor:
Henry T. Hsueh, Renee Ti Chou, Usha Rai, Wathsala Liyanage, Yoo Chun Kim, Matthew B. Appell, Jahnavi Pejavar, Kirby T. Leo, Charlotte Davison, Patricia Kolodziejski, Ann Mozzer, HyeYoung Kwon, Maanasa Sista, Nicole M. Anders, Avelina Hemingway, Sri Vishnu Kiran Rompicharla, Malia Edwards, Ian Pitha, Justin Hanes, Michael P. Cummings, Laura M. Ensign
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-19 (2023)
Abstract Sustained drug delivery strategies have many potential benefits for treating a range of diseases, particularly chronic diseases that require treatment for years. For many chronic ocular diseases, patient adherence to eye drop dosing regimens
Externí odkaz:
https://doaj.org/article/7e5564fd12a045e4b4626040941ea3e5
Autor:
Aditya Josyula, Ann Mozzer, Julia Szeto, Youlim Ha, Nicole Richmond, Seung Woo Chung, Sri Vishnu Kiran Rompicharla, Janani Narayan, Samiksha Ramesh, Justin Hanes, Laura Ensign, Kunal Parikh, Ian Pitha
Publikováno v:
Bioengineering & Translational Medicine, Vol 8, Iss 3, Pp n/a-n/a (2023)
Abstract Biomaterials are implanted in millions of individuals worldwide each year. Both naturally derived and synthetic biomaterials induce a foreign body reaction that often culminates in fibrotic encapsulation and reduced functional lifespan. In o
Externí odkaz:
https://doaj.org/article/5a328a859a0b4ff6842687b015f31c2e
Autor:
Henry T. Hsueh, Yoo-Chun Kim, Ian Pitha, Matthew D. Shin, Cynthia A. Berlinicke, Renee Ti Chou, Elizabeth Kimball, Julie Schaub, Sarah Quillen, Kirby T. Leo, Hyounkoo Han, Amy Xiao, Youngwook Kim, Matthew Appell, Usha Rai, HyeYoung Kwon, Patricia Kolodziejski, Laolu Ogunnaike, Nicole M. Anders, Avelina Hemingway, Joan L. Jefferys, Abhijit A. Date, Charles Eberhart, Thomas V. Johnson, Harry A. Quigley, Donald J. Zack, Justin Hanes, Laura M. Ensign
Publikováno v:
Pharmaceutics, Vol 13, Iss 5, p 647 (2021)
Glaucoma is the leading cause of irreversible blindness worldwide. Elevated intraocular pressure (IOP) is one of the major risk factors for glaucoma onset and progression, and available pharmaceutical interventions are exclusively targeted at IOP low
Externí odkaz:
https://doaj.org/article/3232c89326b24142bbf27c0ff670b9ea
Autor:
Ian Pitha, Siva Kambhampati, Anjali Sharma, Rishi Sharma, Liam McCrea, Ann Mozzer, Rangaramanujam M. Kannan
Publikováno v:
Biomacromolecules
Retinal microglial/macrophage activation and optic nerve (ON) microglial/macrophage activation are glaucoma biomarkers and potential therapeutic targets for this blinding disease. We report targeting of activated microglia by PAMAM dendrimers in a ra
Autor:
null Aditya Josyula, null Ann Mozzer, null Julia Szeto, null Youlim Ha, null Nicole Richmond, null Seung Woo Chung, null Sri Vishnu Kiran Rompicharla, null Janani Narayan, null Samiksha Ramesh, null Justin Hanes, null Laura Ensign, null Kunal Parikh, null Ian Pitha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3b4bb10ec758bd61e27cb885ed559b36
https://doi.org/10.1002/btm2.10487/v3/response1
https://doi.org/10.1002/btm2.10487/v3/response1
Autor:
Ann Mozzer, Ian Pitha
PurposeMyofibroblasts are associated with scleral remodeling in myopia and glaucoma. We showed reduced myofibroblast alignment with topographic cues in sclera can be modeled by cyclic strain exposure of aligned myofibroblasts in vitro. Here, we chara
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0127fe77fec24cf658315c9965076cb1
https://doi.org/10.1101/2022.05.14.491950
https://doi.org/10.1101/2022.05.14.491950
Autor:
Charles G. Eberhart, Cynthia A. Berlinicke, Patricia Kolodziejski, Henry T. Hsueh, Nicole M. Anders, Kirby T. Leo, Matthew B. Appell, Renee Ti Chou, Hyounkoo Han, Hye Young Kwon, Ian Pitha, Avelina Hemingway, Yoo Chun Kim, Usha Rai, Justin Hanes, Matthew D. Shin, Laura M. Ensign, Donald J. Zack
Publikováno v:
Drug Deliv Transl Res
While eye drops are the most common ocular dosage form, eye drops for treating diseases of the posterior segment (retina, choroid, optic nerve) have yet to be developed. In glaucoma, eye drops are used extensively for delivering intraocular pressure
Autor:
Matthew B. Appell, Ian Pitha, Renee Ti Chou, Abhijit A. Date, Laura M. Ensign, Charles G. Eberhart, Matthew D. Shin, Cynthia A. Berlinicke, Nicole M. Anders, Usha Rai, Hyounkoo Han, Joan L. Jefferys, Henry T. Hsueh, Avelina Hemingway, Elizabeth C. Kimball, Sarah Quillen, Thomas V. Johnson, Justin Hanes, Amy Xiao, Harry A. Quigley, Donald J. Zack, Yoo Chun Kim, Kirby T. Leo, Laolu Ogunnaike, Patricia Kolodziejski, Julie Schaub, Youngwook Kim, Hye Young Kwon
Publikováno v:
Pharmaceutics, Vol 13, Iss 647, p 647 (2021)
Pharmaceutics
Volume 13
Issue 5
Pharmaceutics
Volume 13
Issue 5
Glaucoma is the leading cause of irreversible blindness worldwide. Elevated intraocular pressure (IOP) is one of the major risk factors for glaucoma onset and progression, and available pharmaceutical interventions are exclusively targeted at IOP low
Publikováno v:
Ophthalmology Glaucoma. 5:336
Publikováno v:
Drug Deliv Transl Res
Implantable biomaterials are essential surgical devices, extending and improving the quality of life of millions of people globally. Advances in materials science, manufacturing, and in our understanding of the biological response to medical device i