Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Ian P. Y. Lam"'
Publikováno v:
Translational Cancer Research
Background Triple-negative breast cancer (TNBC), an aggressive breast cancer subtype, is associated with poor prognosis and high mortality rate. In the search for effective therapeutic options, preclinical studies have suggested using systemic oxygen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::679ee2864ff011bf7d15841b430eb9e9
https://pubmed.ncbi.nlm.nih.gov/35116399
https://pubmed.ncbi.nlm.nih.gov/35116399
Publikováno v:
PLoS ONE, Vol 7, Iss 6, p e39913 (2012)
Osmoregulation via maintenance of water and salt homeostasis is a vital process. In the brain, a functional secretin (SCT) and secretin receptor (SCTR) axis has recently been shown to mediate central actions of angiotensin II (ANGII), including initi
Externí odkaz:
https://doaj.org/article/da6e0d38ea954d6b98992314de9498f8
Autor:
Hubert Vaudry, Jessica Y. S. Chu, Francis K.Y. Siu, Billy K. C. Chow, Ian P. Y. Lam, Leo T. O. Lee, Vien H. Y. Lee
Publikováno v:
The FASEB Journal. 24:5024-5032
Fluid balance is critical to life and hence is tightly controlled in the body. Angiotensin II (ANGII), one of the most important components of this regulatory system, is recognized as a dipsogenic hormone that stimulates vasopressin (VP) expression a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1c3d391f11da13d16be155e14b50113e
https://doi.org/10.1096/fj.10.165399
https://doi.org/10.1096/fj.10.165399
Autor:
Lai Nar Tung, Kin Tak Chan, Ho Yu Lam, Fei Chuen Tzang, Sze Hang Lau, Sui Yi Kwok, Ian P. Y. Lam, Cornelia Man, Simon Law, Heron Han, Daniel K. Tong, Nikki P. Lee, Mei Yuk Choi, Bing L. Wong
Publikováno v:
Cancer chemotherapy and pharmacology. 76(6)
Adjunct chemoradiation is offered to unresectable esophageal squamous cell carcinoma (ESCC) patients, while its use is limited in tumors with strong resistance. Oxygen carriers or anti-hypoxic drugs belong to an emerging class of regulators that can
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::24b83a5df73a90dbbce73ff8770672b8
https://pubmed.ncbi.nlm.nih.gov/26553104
https://pubmed.ncbi.nlm.nih.gov/26553104
Publikováno v:
Regulatory Peptides. 137:95-104
Secretin, a 27-amino acid gastrointestinal peptide, was initially discovered based on its activities in stimulating pancreatic juice. In the past 20 years, secretin was demonstrated to exhibit pleiotropic functions in many different tissues and more
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e26ed706e8d564c6a7e33350c0c6e625
https://doi.org/10.1016/j.regpep.2006.02.011
https://doi.org/10.1016/j.regpep.2006.02.011
Publikováno v:
Annals of the New York Academy of Sciences. 1070:371-375
Previous studies have demonstrated the transcriptional repressive property of the atypical nuclear receptor, small heterodimer partner (SHP), on NeuroD. NeuroD is a basic helix-loop-helix transcription factor that has also been shown to be important
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e4faa997102c78176128007bfc6d3f8b
https://doi.org/10.1196/annals.1317.047
https://doi.org/10.1196/annals.1317.047
Publikováno v:
PLoS ONE
PLoS ONE, Vol 7, Iss 6, p e39913 (2012)
PLoS ONE, Vol 7, Iss 6, p e39913 (2012)
Osmoregulation via maintenance of water and salt homeostasis is a vital process. In the brain, a functional secretin (SCT) and secretin receptor (SCTR) axis has recently been shown to mediate central actions of angiotensin II (ANGII), including initi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::123ea5e6711083ad20fc582565967567
http://europepmc.org/articles/PMC3382582
http://europepmc.org/articles/PMC3382582
Publikováno v:
American journal of physiology. Gastrointestinal and liver physiology. 297(1)
Small heterodimer partner (SHP) is an orphan nuclear receptor in which gene expression can be upregulated by bile acids. It regulates its target genes by repressing the transcriptional activities of other nuclear receptors including NeuroD, which has
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cf46b218de4dd09348eb637db509f4df
https://pubmed.ncbi.nlm.nih.gov/19372104
https://pubmed.ncbi.nlm.nih.gov/19372104
Publikováno v:
Journal of molecular neuroscience : MN. 36(1-3)
Secretin is a peptide hormone playing multiple functions in the brain–gut axis. In this report, we investigated, by promoter analysis, the potential function of the variable of tandem repeats (VNTR), located at the 5′ upstream region of the human
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5a060bf862259ada44de9563e636af16
https://pubmed.ncbi.nlm.nih.gov/18566919
https://pubmed.ncbi.nlm.nih.gov/18566919
Publikováno v:
International review of cytology. 265
The discovery of secretin initiated the field of endocrinology. Over the past century, multiple gastrointestinal functions of secretin have been extensively studied, and it was discovered that the principal function of this peptide in the gastrointes
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::3c3628020cd401c7a539c10674ee4f05
https://pubmed.ncbi.nlm.nih.gov/18275888
https://pubmed.ncbi.nlm.nih.gov/18275888