Zobrazeno 1 - 10
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pro vyhledávání: '"Ian Moench"'
Publikováno v:
Frontiers in Physiology, Vol 9 (2018)
Efficient excitation-contraction coupling in ventricular myocytes depends critically on the presence of the t-tubular network. It has been recently demonstrated that cholesterol, a major component of the lipid bilayer, plays an important role in long
Externí odkaz:
https://doaj.org/article/b7f4c625633e42498a9a5b12608d88be
Autor:
Nicholas J. Agard, Peter S. Dragovich, Ryan L. Kelly, Shion A. Lim, Allison M. Beal, Ian Moench, Anna M. Gram, Pei-Pei Kung, Daša Lipovšek
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::35ae0feec8bc4e0efe319f5c4f279989
https://doi.org/10.29200/acsmedchemrev-v56.ch22
https://doi.org/10.29200/acsmedchemrev-v56.ch22
Publikováno v:
Am J Physiol Heart Circ Physiol
Cardiac t tubules undergo significant remodeling in various pathological and experimental conditions, which can be associated with mechanical or osmotic stress. In particular, it has been shown that removal of hyposmotic stress can lead to sealing of
Autor:
Ian Moench, Christine G. Schnackenberg, Gatto Gregory J, John R. Toomey, Joanne Kuziw, Karpagam Aravindhan, Robert N. Willette
Publikováno v:
Journal of the Endocrine Society
Increased fibroblast growth factor 23 (FGF23) levels are an independent predictor for adverse cardiac events suggesting a role as a link that drives cardiomyopathic changes in cardiorenal syndrome. The search for the underlying mechanism driving this
Publikováno v:
Frontiers in Physiology
Frontiers in Physiology, Vol 9 (2018)
Frontiers in Physiology, Vol 9 (2018)
Efficient excitation-contraction coupling in ventricular myocytes depends critically on the presence of the t-tubular network. It has been recently demonstrated that cholesterol, a major component of the lipid bilayer, plays an important role in long
Publikováno v:
American Journal of Physiology-Heart and Circulatory Physiology. 311:H229-H238
Cardiac t-tubules are critical for efficient excitation-contraction coupling but become significantly remodeled during various stress conditions. However, the mechanisms by which t-tubule remodeling occur are poorly understood. Recently, we demonstra
Publikováno v:
Experimental Physiology. 98:1164-1177
It has been recently shown that various stress-inducing manipulations in isolated ventricular myocytes may lead to significant remodeling of t-tubules. Osmotic stress is one of the most common complications in various experimental and clinical settin
Publikováno v:
Biophysical Journal. 104(2)
It has been recently shown that various stress-inducing manipulations in isolated ventricular cardiac myocytes may lead to significant remodeling of t-tubules. Osmotic stress is one of the most common complications in various experimental and clinica
Sulindac confers high level ischemic protection to the heart through late preconditioning mechanisms
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America. 106(46)
We have recently shown that sulindac, an anti-inflammatory drug, enhances the killing of cancer cells, but not normal cells, under conditions of oxidative stress, by mechanisms unrelated to its cyclooxygenase (COX) inhibition. To further study the pr
Publikováno v:
ResearcherID
Cardiac t-tubules are critical for efficient excitation-contraction coupling and undergo significant remodeling during various experimental and clinical stress conditions including heart failure. Recently, we have shown that recovery of ventricular m