Zobrazeno 1 - 10
of 107
pro vyhledávání: '"Ian Martins"'
Autor:
Gemma Cadby, Corey Giles, Phillip E. Melton, Kevin Huynh, Natalie A. Mellett, Thy Duong, Anh Nguyen, Michelle Cinel, Alex Smith, Gavriel Olshansky, Tingting Wang, Marta Brozynska, Mike Inouye, Nina S. McCarthy, Amir Ariff, Joseph Hung, Jennie Hui, John Beilby, Marie-Pierre Dubé, Gerald F. Watts, Sonia Shah, Naomi R. Wray, Wei Ling Florence Lim, Pratishtha Chatterjee, Ian Martins, Simon M. Laws, Tenielle Porter, Michael Vacher, Ashley I. Bush, Christopher C. Rowe, Victor L. Villemagne, David Ames, Colin L. Masters, Kevin Taddei, Matthias Arnold, Gabi Kastenmüller, Kwangsik Nho, Andrew J. Saykin, Xianlin Han, Rima Kaddurah-Daouk, Ralph N. Martins, John Blangero, Peter J. Meikle, Eric K. Moses
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-17 (2022)
Dysregulation of lipid metabolism is associated with coronary artery disease (CAD). Here, the authors perform GWAS of the serum lipidome to identify variants associated with lipid species that are putatively in the mechanistic pathway to CAD.
Externí odkaz:
https://doaj.org/article/1160229aa3d04cc8a6b15b682b0f47a7
Autor:
Steve Pedrini, Pratishtha Chatterjee, Akinori Nakamura, Michelle Tegg, Eugene Hone, Stephanie R. Rainey-Smith, Christopher C. Rowe, Vincent Dore, Victor L. Villemagne, David Ames, Naoki Kaneko, Sam L. Gardener, Kevin Taddei, Binosha Fernando, Ian Martins, Prashant Bharadwaj, Hamid R. Sohrabi, Colin L. Masters, Belinda Brown, Ralph N. Martins
Publikováno v:
Frontiers in Aging Neuroscience, Vol 14 (2022)
Previous studies have indicated that physical activity may be beneficial in reducing the risk for Alzheimer's disease (AD), although the underlying mechanisms are not fully understood. The goal of this study was to evaluate the relationship between h
Externí odkaz:
https://doaj.org/article/1fb4baa934654da2abc0ab50c96fcaca
Autor:
Kevin Huynh, Wei Ling Florence Lim, Corey Giles, Kaushala S. Jayawardana, Agus Salim, Natalie A. Mellett, Adam Alexander T. Smith, Gavriel Olshansky, Brian G. Drew, Pratishtha Chatterjee, Ian Martins, Simon M. Laws, Ashley I. Bush, Christopher C. Rowe, Victor L. Villemagne, David Ames, Colin L. Masters, Matthias Arnold, Kwangsik Nho, Andrew J. Saykin, Rebecca Baillie, Xianlin Han, Rima Kaddurah-Daouk, Ralph N. Martins, Peter J. Meikle
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-11 (2020)
The onset and pathology of Alzheimer’s disease (AD) is associated with changes to lipid metabolism. Here, the authors analysed 569 lipids from 32 classes and subclasses in two independent patient cohorts to identify key lipid pathways to link the p
Externí odkaz:
https://doaj.org/article/4dd529924c75463b9ab9f71c074acad6
Autor:
Adam Alexander T. Smith, Christopher C. Rowe, Andrew J. Saykin, Rebecca Baillie, Brian G. Drew, Matthias Arnold, Wei Ling Florence Lim, Xianlin Han, Gavriel Olshansky, Victor L. Villemagne, Corey Giles, Natalie A. Mellett, Ashley I. Bush, Rima Kaddurah-Daouk, Peter J. Meikle, Ralph N. Martins, Agus Salim, Simon M. Laws, Pratishtha Chatterjee, Kevin Huynh, Kaushala S. Jayawardana, David Ames, Ian Martins, Colin L. Masters, Kwangsik Nho
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-11 (2020)
Nat. Commun. 11:5698 (2020)
Nature Communications
Nat. Commun. 11:5698 (2020)
Nature Communications
Changes to lipid metabolism are tightly associated with the onset and pathology of Alzheimer’s disease (AD). Lipids are complex molecules comprising many isomeric and isobaric species, necessitating detailed analysis to enable interpretation of bio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::57c5b3e38a444a6d2835280c1c346361
https://doaj.org/article/4dd529924c75463b9ab9f71c074acad6
https://doaj.org/article/4dd529924c75463b9ab9f71c074acad6
Autor:
Kaj Blennow, Stephanie J. Fuller, Hamid R. Sohrabi, Yunqi Wu, Tejal M. Shah, Ralph N. Martins, Steve Pedrini, Pratishtha Chatterjee, Cintia B. Dias, Kevin Taddei, Eugene Hone, Heidi Hillebrandt, Kathryn Goozee, Wei Ling Florence Lim, Matthew J. McKay, Prita R. Asih, Preeti Dave, Atul Bhatnagar, Ian Martins, Yeo-Jin Cheong, Victor L. Villemagne, Sunil Gupta, Michelle Tegg, Henrik Zetterberg
Publikováno v:
Journal of Neurochemistry. 159:389-402
Alzheimer's disease (AD) is a progressive neurodegenerative disorder that currently has no cure. Identifying biochemical changes associated with neurodegeneration prior to symptom onset, will provide insight into the biological mechanisms associated
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8dc61b4fc011f8f8842a7ea225a84c10
https://doi.org/10.1111/jnc.15128
https://doi.org/10.1111/jnc.15128
Autor:
Corey Giles, Ashley I. Bush, David Ames, Ian Martins, Victor L. Villemagne, Kevin Huynh, Kaushala S. Jayawardana, Christopher C. Rowe, Colin L. Masters, Brian G. Drew, Wei Ling Florence Lim, Simon M. Laws, Natalie A. Mellett, Peter J. Meikle, Ralph N. Martins, Pratishtha Chatterjee
Publikováno v:
Journal of Alzheimer's Disease
Background Lipid metabolism is altered in Alzheimer's disease (AD); however, the relationship between AD risk factors (age, APOEɛ4, and gender) and lipid metabolism is not well defined. Objective We investigated whether altered lipid metabolism asso
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::68b8f4f5c168626d5ea5c18870dec5d5
https://doi.org/10.3233/jad-191304
https://doi.org/10.3233/jad-191304
Autor:
Tingting Wang, Kevin Huynh, Corey Giles, Wei Ling Florence Lim, Thy Duong, Natalie A. Mellett, Alexander Smith, Gavriel Olshansky, Brian G. Drew, Gemma Cadby, Phillip E. Melton, Joseph Hung, John Beilby, Gerald F. Watts, Pratishtha Chatterjee, Ian Martins, Simon M. Laws, Ashley I. Bush, Christopher C. Rowe, Victor L. Villemagne, David Ames, Colin L. Masters, Matthias Arnold, Gabi Kastenmüller, Kwangsik Nho, Andrew J. Saykin, Rebecca Baillie, Xianlin Han, Ralph N. Martins, Eric Moses, Rima F. Kaddurah‐Daouk, Peter J Meikle
Publikováno v:
Alzheimer's & Dementia. 17
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2363bb9b8ada80a0baf4cb3f92bb6077
https://doi.org/10.1002/alz.056703
https://doi.org/10.1002/alz.056703
Autor:
Tingting Wang, Kevin Huynh, Corey Giles, Natalie A Mellett, Thy Duong, Anh Nguyen, Wei Ling Florence Lim, Alex AT Smith, Gavriel Olshansky, Gemma Cadby, Joseph Hung, Jennie Hui, John Beilby, Gerald F Watts, Pratishtha Chatterjee, Ian Martins, Simon M Laws, Ashley I Bush, Christopher C Rowe, Victor L Villemagne, David Ames, Colin L Masters, Kevin Taddei, Vincent Doré, Jürgen Fripp, Matthias Arnold, Gabi Kastenmüller, Kwangsik Nho, Andrew J Saykin, Rebecca Baillie, Xianlin Han, Ralph N Martins, Eric K Moses, Rima Kaddurah‐Daouk, Peter J Meikle
Publikováno v:
Alzheimer'sdementia : the journal of the Alzheimer's AssociationREFERENCES. 18(11)
The apolipoprotein E (APOE) genotype is the strongest genetic risk factor for late-onset Alzheimer's disease. However, its effect on lipid metabolic pathways, and their mediating effect on disease risk, is poorly understood.We performed lipidomic ana
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e4cfc8d4a37b17f060369aec008a8bf9
https://pubmed.ncbi.nlm.nih.gov/35077012
https://pubmed.ncbi.nlm.nih.gov/35077012
Autor:
Steve Pedrini, Pratishtha Chatterjee, Akinori Nakamura, Michelle Tegg, Eugene Hone, Stephanie R. Rainey-Smith, Christopher C. Rowe, Vincent Dore, Victor L. Villemagne, David Ames, Naoki Kaneko, Sam L. Gardener, Kevin Taddei, Binosha Fernando, Ian Martins, Prashant Bharadwaj, Hamid R. Sohrabi, Colin L. Masters, Belinda Brown, Ralph N. Martins
Publikováno v:
Frontiers in aging neuroscience. 14
Previous studies have indicated that physical activity may be beneficial in reducing the risk for Alzheimer's disease (AD), although the underlying mechanisms are not fully understood. The goal of this study was to evaluate the relationship between h
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e7369c53206eab78e76d1558f053f0ec
https://pubmed.ncbi.nlm.nih.gov/35418852
https://pubmed.ncbi.nlm.nih.gov/35418852
Autor:
Gemma Cadby, Michael Vacher, Christopher C. Rowe, Eric K. Moses, Anh Nguyen, John Beilby, Jennie Hui, David Ames, Ian Martins, Marta Brozynska, Ashley I. Bush, Naomi R. Wray, Tingting Wang, Simon M. Laws, Ralph N. Martins, John Blangero, Gabi Kastenmüller, Pratishtha Chatterjee, Gavriel Olshansky, Tenielle Porter, Phillip E. Melton, Sonia Shah, Marie-Pierre Dubé, Matthias Arnold, Amir Ariff, Andrew J. Saykin, Corey Giles, Xianlin Han, Michelle Cinel, Kevin Taddei, Wei Ling Florence Lim, Gerald F. Watts, Michael Inouye, Kevin Huynh, Joseph Hung, Nina S. McCarthy, Natalie A. Mellett, Alexander Ian Smith, Peter J. Meikle, Colin L. Masters, Kwangsik Nho, Victor L. Villemagne, Thy Duong, Rima Kaddurah-Daouk
We integrated lipidomics and genomics to unravel the genetic architecture of lipid metabolism and identify genetic variants associated with lipid species that are putatively in the mechanistic pathway to coronary artery disease (CAD). We quantified 5
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0009591bae8412dafa9ae5f917dc84b7
https://doi.org/10.1101/2021.08.20.21261814
https://doi.org/10.1101/2021.08.20.21261814
