Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Ian Mahar"'
Autor:
Katharine J. Babcock, Bobak Abdolmohammadi, Patrick T. Kiernan, Ian Mahar, Jonathan D. Cherry, Victor E. Alvarez, Lee E. Goldstein, Thor D. Stein, Ann C. McKee, Bertrand R. Huber
Publikováno v:
Acta Neuropathologica Communications, Vol 10, Iss 1, Pp 1-14 (2022)
Abstract Exposure to military blast and repetitive head impacts (RHI) in contact sports is associated with increased risk of long-term neurobehavioral sequelae and cognitive deficits, and the neurodegenerative disease chronic traumatic encephalopathy
Externí odkaz:
https://doaj.org/article/3671b8af5d384f5184db303fb11dbedd
Autor:
Jonathan D. Cherry, Jesse Mez, John F. Crary, Yorghos Tripodis, Victor E. Alvarez, Ian Mahar, Bertrand R. Huber, Michael L. Alosco, Raymond Nicks, Bobak Abdolmohammadi, Patrick T. Kiernan, Laney Evers, Sarah Svirsky, Katharine Babcock, Hannah M. Gardner, Gaoyuan Meng, Christopher J. Nowinski, Brett M. Martin, Brigid Dwyer, Neil W. Kowall, Robert C. Cantu, Lee E. Goldstein, Douglas I. Katz, Robert A. Stern, Lindsay A. Farrer, Ann C. McKee, Thor D. Stein
Publikováno v:
Acta Neuropathologica Communications, Vol 6, Iss 1, Pp 1-9 (2018)
Abstract The genetic basis of chronic traumatic encephalopathy (CTE) is poorly understood. Variation in transmembrane protein 106B (TMEM106B) has been associated with enhanced neuroinflammation during aging and with TDP-43-related neurodegenerative d
Externí odkaz:
https://doaj.org/article/00003741594643f4996e2555a01e03c7
Autor:
Ian Mahar, Rosemary C Bagot, Maria Antonietta Davoli, Sharon Miksys, Rachel F Tyndale, Claire-Dominique Walker, Marissa Maheu, Sheng-Hai Huang, Tak Pan Wong, Naguib Mechawar
Publikováno v:
PLoS ONE, Vol 7, Iss 5, p e37219 (2012)
The influence of developmental nicotine exposure on the brain represents an important health topic in light of the popularity of nicotine replacement therapy (NRT) as a smoking cessation method during pregnancy.In this study, we used a model of NRT d
Externí odkaz:
https://doaj.org/article/df1c9426053b475295e314d66883f37b
Autor:
Ian Mahar, Stephanie Tan, Maria Antonietta Davoli, Sergio Dominguez-Lopez, Calvin Qiang, Adeline Rachalski, Gustavo Turecki, Naguib Mechawar
Publikováno v:
PLoS ONE, Vol 6, Iss 10, p e26610 (2011)
BackgroundAdult hippocampal neurogenesis has been implicated in the mechanism of antidepressant action, and neurotrophic factors can mediate the neurogenic changes underlying these effects. The neurotrophic factor neuregulin-1 (NRG1) is involved in m
Externí odkaz:
https://doaj.org/article/1d30f46b6fa04af2a82f01b6af48e597
Autor:
Christopher J. Nowinski, Brett M. Martin, Todd M. Solomon, Joseph Palmisano, Zachary H. Baucom, Robert S. Stern, Ann C. McKee, Yorghos Tripodis, Nicole Saltiel, Michael L. Alosco, Douglas I. Katz, Raymond Nicks, Neil W. Kowall, Madeline Uretsky, Ian Mahar, Brigid Dwyer, Philip H. Montenigro, Bobak Abdolmohammadi, Victor E. Alvarez, Bertrand R. Huber, Robert C. Cantu, Thor D. Stein, Jonathan D. Cherry, Daniel H. Daneshvar, Jesse Mez, Lee E. Goldstein
Publikováno v:
Alzheimer's & Dementia
Introduction Validity of the 2014 traumatic encephalopathy syndrome (TES) criteria, proposed to diagnose chronic traumatic encephalopathy (CTE) in life, has not been assessed. Methods A total of 336 consecutive brain donors exposed to repetitive head
Autor:
Patrick T. Kiernan, Joseph Palmisano, Christopher J. Nowinski, Michael L. Alosco, Brett M. Martin, Laura Marshall, Neil W. Kowall, Jesse Mez, Yorghos Tripodis, Ian Mahar, Michael D. McClean, Rhoda Au, Thor D. Stein, Jennifer Weuve, Alicia S. Chua, Lee E. Goldstein, Brigid Dwyer, Victor E. Alvarez, Robert S. Stern, Jonathan D. Cherry, Bobak Abdolmohammadi, Ann C. McKee, Bertrand R. Huber, Robert C. Cantu, Douglas I. Katz, Laney Evers, Daniel H. Daneshvar
Publikováno v:
Annals of Neurology
Objective Chronic traumatic encephalopathy (CTE) is a neurodegenerative disease associated with exposure to contact and collision sports, including American football. We hypothesized a dose–response relationship between duration of football played
Autor:
Daniel H. Daneshvar, Jesse Mez, Michael L. Alosco, Zachary H. Baucom, Ian Mahar, Christine M. Baugh, Jhaqueline P. Valle, Jennifer Weuve, Sabrina Paganoni, Robert C. Cantu, Ross D. Zafonte, Robert A. Stern, Thor D. Stein, Yorghos Tripodis, Christopher J. Nowinski, Ann C. McKee
Publikováno v:
JAMA Network Open
Key Points Question What are the incidence and mortality rates of amyotrophic lateral sclerosis (ALS) in athletes who played in the National Football League (NFL)? Findings In this cohort study of all 19 423 NFL athletes who debuted between 1960 and
Autor:
Douglas I. Katz, Raymond Nicks, Jacob S. Friedberg, Joseph Palmisano, Ann C. McKee, Bertrand R. Huber, Robert C. Cantu, Jonathan D. Cherry, Thor D. Stein, Brett M. Martin, Neil W. Kowall, Ian Mahar, Michael L. Alosco, Oliver J. Standring, Hannah M. Gardner, Morgan Pothast, Jesse Mez, Weiming Xia, Yorghos Tripodis, Brigid Dwyer, Victor E. Alvarez, Robert S. Stern, Gaoyuan Meng, Lee E. Goldstein, Alicia S. Chua
Publikováno v:
Acta Neuropathol
Cerebral amyloid angiopathy (CAA) consists of beta-amyloid deposition in the walls of the cerebrovasculature and is commonly associated with Alzheimer’s disease (AD). However, the association of CAA with repetitive head impacts (RHI) and with chron
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0d5ec889c5a7f438502a25aec6de6f87
https://europepmc.org/articles/PMC6689453/
https://europepmc.org/articles/PMC6689453/
Chronic traumatic encephalopathy (CTE) is a progressive, neurodegenerative tauopathy associated with exposure to repetitive head injury, including concussions and subconcussions. Clinical features of CTE consist of abnormalities in behavior, includin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0865505a45617be2a9afbc89f0c45a37
https://doi.org/10.1093/oxfordhb/9780190664121.013.29
https://doi.org/10.1093/oxfordhb/9780190664121.013.29
Autor:
Katharine J. Babcock, Jonathan D. Cherry, Lee E. Goldstein, Thor D. Stein, John F. Crary, Neil W. Kowall, Hannah M. Gardner, Gaoyuan Meng, Yorghos Tripodis, Jesse Mez, Patrick T. Kiernan, Christopher J. Nowinski, Michael L. Alosco, Brett M. Martin, Robert S. Stern, Ann C. McKee, Ian Mahar, Sarah Svirsky, Bobak Abdolmohammadi, Bertrand R. Huber, Robert C. Cantu, Douglas I. Katz, Laney Evers, Raymond Nicks, Brigid Dwyer, Victor E. Alvarez, Lindsay A. Farrer
Publikováno v:
Acta Neuropathologica Communications
Acta Neuropathologica Communications, Vol 6, Iss 1, Pp 1-9 (2018)
Acta Neuropathologica Communications, Vol 6, Iss 1, Pp 1-9 (2018)
The genetic basis of chronic traumatic encephalopathy (CTE) is poorly understood. Variation in transmembrane protein 106B (TMEM106B) has been associated with enhanced neuroinflammation during aging and with TDP-43-related neurodegenerative disease, a