Zobrazeno 1 - 10
of 142
pro vyhledávání: '"Ian M. Carr"'
Autor:
Aidyn Kydyrmanov, Kobey Karamendin, Yermukhammet Kassymbekov, Marat Kumar, Shynar Mazkirat, Symbat Suleimenova, Mirgaliy Baimukanov, Ian M. Carr, Simon J. Goodman
Publikováno v:
Frontiers in Marine Science, Vol 10 (2023)
Disease surveillance of marine mammal populations is essential to understand the causes of strandings, identify potential threats to animal health, and to support development of conservation strategies. Here we report the first large multi-pathogen s
Externí odkaz:
https://doaj.org/article/ffaf9c0dc7c24a949782c0107b7baf3d
Autor:
Antonios Psarras, Adewonuola Alase, Agne Antanaviciute, Ian M. Carr, Md Yuzaiful Md Yusof, Miriam Wittmann, Paul Emery, George C. Tsokos, Edward M. Vital
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-18 (2020)
Type I interferon drives autoimmune pathology in SLE and has been assumed to come predominantly from plasmacytoid dendritic cells (pDCs). Here, the authors show that prior to the onset of SLE, pDCs lose multiple immunogenic functions and, instead, no
Externí odkaz:
https://doaj.org/article/bbb2318833484129bd8e0fdec78640c3
Autor:
Elena Valsecchi, Antonella Arcangeli, Roberto Lombardi, Elizabeth Boyse, Ian M. Carr, Paolo Galli, Simon J. Goodman
Publikováno v:
Frontiers in Marine Science, Vol 8 (2021)
Marine environmental DNA (eDNA) is an important tool for biodiversity research and monitoring but challenges remain in scaling surveys over large spatial areas, and increasing the frequency of sampling in remote locations at reasonable cost. Here we
Externí odkaz:
https://doaj.org/article/557328c1c0f44abf9c106bb7743b7854
Autor:
Mark A. Hull, Richard J. Cuthbert, C. W. Stanley Ko, Daniel J. Scott, Elizabeth J. Cartwright, Gillian Hawcroft, Sarah L. Perry, Nicola Ingram, Ian M. Carr, Alexander F. Markham, Constanze Bonifer, P. Louise Coletta
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-14 (2017)
Abstract Genetic deletion or pharmacological inhibition of cyclooxygenase (COX)-2 abrogates intestinal adenoma development at early stages of colorectal carcinogenesis. COX-2 is localised to stromal cells (predominantly macrophages) in human and mous
Externí odkaz:
https://doaj.org/article/e481426f4bf8467fae7994ac44635d17
Autor:
Imeshi Wijetunga, Laura E. McVeigh, Antonia Charalambous, Agne Antanaviciute, Ian M. Carr, Amit Nair, K. Raj Prasad, Nicola Ingram, P. Louise Coletta
Publikováno v:
Cancers, Vol 12, Iss 10, p 2817 (2020)
Cholangiocarcinoma (CCA) is a rare disease with poor outcomes and limited research efforts into novel treatment options. A systematic review of CCA biomarkers was undertaken to identify promising biomarkers that may be used for theranosis (therapy an
Externí odkaz:
https://doaj.org/article/6ed8ee726d9442d3bfcfd03fad0bf45d
Autor:
Philip A. Robinson, D. Mark Pritchard, Ian M. Carr, Kazuma Danjo, Michael F. Dixon, Anthony H.T. Jeremy, Cedric Duval, Jean E. Crabtree
Publikováno v:
Pathogens, Vol 2, Iss 4, Pp 571-590 (2013)
Helicobacter pylori transactivates the Epidermal Growth Factor Receptor (EGFR) and predisposes to gastric cancer development in humans and animal models. To examine the importance of EGFR signalling to gastric pathology, this study investigated wheth
Externí odkaz:
https://doaj.org/article/47aa089efc3c448b92bfa539972f21df
Autor:
Kylie K. Reed, Ava E. Silverman, Afrouz Abbaspour, Kyle S. Burger, Cynthia M. Bulik, Ian M. Carroll
Publikováno v:
Journal of Eating Disorders, Vol 12, Iss 1, Pp 1-15 (2024)
Abstract Background Weight gain and nutritional rehabilitation are essential first steps to achieve medical stabilization in anorexia nervosa, and frequent resistance to weight gain requires patients to consume high kilocalorie loads. Adaptive hypome
Externí odkaz:
https://doaj.org/article/3221fda4a7f948fb8209e795294668ba
Autor:
David T. Bonthron, Rachel Robinson, Rowena E. Mitchell, Christopher M. Watson, Sérgio D.J. Pena, George A. Tanteles, Laura A. Crinnion, Helen Lindsay, Ian M. Carr, Nick Camm, Domhnall J. O' Halloran, Caroline Joyce
Publikováno v:
Laboratory Investigation. 101:442-449
Short-read next generation sequencing (NGS) has become the predominant first-line technique used to diagnose patients with rare genetic conditions. Inherent limitations of short-read technology, notably for the detection and characterization of compl
Autor:
Christopher W. Wasson, Jörg H W Distler, Clarissa Corinaldesi, Rebecca L. Ross, Agne Antanaviciute, Clive S. McKimmie, Francesco Del Galdo, Yasser M. El-Sherbiny, Steve Holmes, Antonio Carriero, Ian M. Carr, Gemma Migneco
Publikováno v:
Annals of the Rheumatic Diseases
ObjectivesPlasmacytoid dendritic cells (pDC) have been implicated in the pathogenesis of autoimmune diseases, such as scleroderma (SSc). However, this has been derived from indirect evidence using ex vivo human samples or mouse pDC in vivo. We have d
Autor:
Andrea Galimberti, Elena Valsecchi, Roberto Lombardi, Ian M. Carr, Laura M. Castellano, Paolo Galli, Jonas Bylemans, Simon J. Goodman
Publikováno v:
Environmental DNA, Vol 2, Iss 4, Pp 460-476 (2020)
Metabarcoding studies using environmental DNA (eDNA) and high‐throughput sequencing (HTS) are rapidly becoming an important tool for assessing and monitoring marine biodiversity, detecting invasive species, and supporting basic ecological research.