Zobrazeno 1 - 10
of 78
pro vyhledávání: '"Ian M. Burr"'
Autor:
Shigeru Kiyama, Iekuni Ichikawa, Ian M. Burr, Agnes B. Fogo, Valentina Kon, Toshimasa Yoshioka
Publikováno v:
Kidney International. 47(2):536-546
Strategic locus for the activation of the superoxide dismutase gene in the nephron. Upon exposure to a transient ischemia, the distal tubule of the kidney often escapes the severe damage which afflicts the proximal tubule. To ascertain whether this f
Autor:
Gary A. Visner, Jonathan D. Hurt, William C. Dougall, Ian M. Burr, Jan-Ling Hsu, Harry S. Nick
Publikováno v:
Nucleic Acids Research. 20:2985-2990
The mitochondrial enzyme, manganese superoxide dismutase (MnSOD) is an integral component of the cell's defense against superoxide-mediated cellular damage. We have isolated and characterized four cDNA clones and the structural gene for rat MnSOD. No
Publikováno v:
American Review of Respiratory Disease. 144:600-605
The purpose of this study was to determine the effect of endotoxin on the development of vascular and airway dysfunction during O2 toxicity. Sheep were prepared for chronic measurement of vascular pressures, cardiac output, gas exchange, and collecti
Autor:
Tracy Moore-Jarrett, Toshimasa Yoshioka, Iekuni Ichikawa, Teresa Bills, Ian M. Burr, Harry L. Greene
Publikováno v:
Kidney International. 38:282-288
Role of intrinsic antioxidant enzymes in renal oxidant injury. To investigate the functional role of renal intrinsic antioxidant enzymes (AOEs), the levels of AOE activities in isolated glomeruli and the changes in renal function to oxidant insults w
Publikováno v:
The Journal of Pediatrics. 85:792-795
A 16-year-old boy with type I GSD has been treated with parenteral nutrition, continuous intragastric feeding, and portacaval shunt. The effects of these treatment methods have been compared with reference to changes in blood chemical values, platele
Publikováno v:
Metabolism. 28:707-715
The acute hormonal and amino acid responses to differing food substrates were examined in type I glycogen storage disease. Ingestion of a glucose load or a glucose-plus-beef meal caused an acute fall in the initially elevated plasma glucagon, alanine
Publikováno v:
The Journal of Clinical Endocrinology & Metabolism. 42:918-925
Both pregnenolone and 17-OH-pregnenolone were found to be higher in the plasma of patients with poorly controlled congential adrenal hyperplasia than in normal subjects. The plasma levels of these precursor steroids were significantly correlated with
Autor:
Younger Rk, Harry L. Greene, Ian M. Burr, Peter W. Stacpoole, Larry L. Swift, Alfred E. Slonim
Publikováno v:
The American Journal of Medicine. 72:889-893
Homozygous familial hypercholesterolemia is refractory to standard dietary or drug therapy. Recent studies, however, suggest that a high-carbohydrate/low-fat diet may reduce circulating cholesterol levels in normal or hyperlipidemic subjects. In this
Publikováno v:
Lipids. 23:559-563
Although copper has been demonstrated to promote lipid peroxidation in a number of systems, the mechanisms involved have not been fully defined. In this study, the role of copper in modifying lipid peroxidation has been explored in rat hepatic micros