Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Ian M Sudbery"'
Autor:
Jamie A Greig, Ian M Sudbery, Jonathan P Richardson, Julian R Naglik, Yue Wang, Peter E Sudbery
Publikováno v:
PLoS Pathogens, Vol 11, Iss 1, p e1004630 (2015)
The opportunistic human fungal pathogen, Candida albicans, undergoes morphological and transcriptional adaptation in the switch from commensalism to pathogenicity. Although previous gene-knockout studies have identified many factors involved in this
Externí odkaz:
https://doaj.org/article/846d535c67e340c5a4c64b412dfb7735
Autor:
Alexia Katsarou, Nikolaos Trasanidis, Kanagaraju Ponnusamy, Ioannis V Kostopoulos, Jaime Alvarez-Benayas, Foteini Papaleonidopoulou, Keren Keren, Pierangela MR Sabbattini, Niklas Feldhahn, Maria Papaioannou, Evdoxia Hatjiharissi, Ian M Sudbery, Aristeidis Chaidos, Valentina S Caputo, Anastasios Karadimitris
Publikováno v:
Blood Advances.
Deregulated expression of lineage-affiliated transcription factors is a major mechanism of oncogenesis. However, how deregulation of non-lineage affiliated TF impacts chromatin to initiate oncogenic transcriptional programmes is not well known. To ad
Autor:
Jaime Alvarez-Benayas, Nikolaos Trasanidis, Alexia Katsarou, Kanagaraju Ponnusamy, Aristeidis Chaidos, Philippa C. May, Xiaolin Xiao, Marco Bua, Maria Atta, Irene A. G. Roberts, Holger W. Auner, Evdoxia Hatjiharissi, Maria Papaioannou, Valentina S. Caputo, Ian M. Sudbery, Anastasios Karadimitris
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-16 (2021)
Despite extensive genetic heterogeneity, nearly half of all multiple myeloma (MM) cases are driven by cyclin D2 (CCND2) over-expression. Here the authors dissect the chromatin landscape of MM to provide insights into the transcriptional regulatory la
Externí odkaz:
https://doaj.org/article/3fcdca45e3ee4529b529898c605a8394
Autor:
Chiara Niespolo, Jessica M. Johnston, Sumeet R. Deshmukh, Swapna Satam, Ziyanda Shologu, Oscar Villacanas, Ian M. Sudbery, Heather L. Wilson, Endre Kiss-Toth
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
The pseudokinase TRIB1 controls cell function in a range of contexts, by regulating MAP kinase activation and mediating protein degradation via the COP1 ubiquitin ligase. TRIB1 regulates polarization of macrophages and dysregulated Trib1 expression i
Externí odkaz:
https://doaj.org/article/00a9348182fc4be89e88a4ad4dc40580