Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Ian M Gans"'
Autor:
Karolina M Andralojc, Anne C Campbell, Ashley L Kelly, Markus Terrey, Paige C Tanner, Ian M Gans, Michael J Senter-Zapata, Eraj S Khokhar, Dustin L Updike
Publikováno v:
PLoS Genetics, Vol 13, Iss 2, p e1006611 (2017)
Germ cells contain non-membrane bound cytoplasmic organelles that help maintain germline integrity. In C. elegans they are called P granules; without them, the germline undergoes partial masculinization and aberrant differentiation. One key P-granule
Externí odkaz:
https://doaj.org/article/d5e11391c9da41e6ad9ae9793657bf23
Autor:
Laura Drepanos, Ian M. Gans, Janelle Grendler, Sophia Guitar, J. Heath Fuqua, Nathaniel J. Maki, Andrea R. Tilden, Joel H. Graber, James A. Coffman
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-13 (2023)
Abstract Krüppel-like factor 9 (Klf9) is a ubiquitously expressed transcription factor that is a feedforward regulator of multiple stress-responsive and endocrine signaling pathways. We previously described how loss of Klf9 function affects the tran
Externí odkaz:
https://doaj.org/article/37894aed86f4483480f6e316ff19041a
Autor:
Ian M. Gans, James A. Coffman
Publikováno v:
Frontiers in Physiology, Vol 12 (2021)
Glucocorticoids, vertebrate steroid hormones produced by cells of the adrenal cortex or interrenal tissue, function dynamically to maintain homeostasis under constantly changing and occasionally stressful environmental conditions. They do so by bindi
Externí odkaz:
https://doaj.org/article/747ab4d7497846f8b4c17455f3a111fb
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 9 (2021)
Krüppel-like factor 9 (Klf9) is a feedforward regulator of glucocorticoid receptor (GR) signaling. Here we show that in zebrafish klf9 is expressed with GR-dependent oscillatory dynamics in synchrony with fkbp5, a GR target that encodes a negative f
Externí odkaz:
https://doaj.org/article/09396b52284e4bcaaf5fd8008b11915f
Publikováno v:
SSRN Electronic Journal.
Kruppel-like factor 9 (Klf9) is a feedforward regulator of glucocorticoid receptor (GR) signaling. We asked if klf9 interacts with fkbp5, a negative feedback regulator of the GR implicated in stress-induced psychiatric and metabolic disorders. We sho
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::eab3fd972e84dd1c068908228adfda08
https://doi.org/10.2139/ssrn.3816951
https://doi.org/10.2139/ssrn.3816951
Autor:
Shusen Zhu, Nathaniel J. Maki, Ian M Gans, Joel H. Graber, Lucie N. Hutchins, Andrea R. Tilden, James A. Coffman, Ellen I. Hartig
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-16 (2020)
Scientific Reports
Scientific Reports
The zebrafish has recently emerged as a model system for investigating the developmental roles of glucocorticoid signaling and the mechanisms underlying glucocorticoid-induced developmental programming. To assess the role of the Glucocorticoid Recept
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::09f6b801fd677c9060c8a5b88d012875
https://doi.org/10.1038/s41598-020-68040-z
https://doi.org/10.1038/s41598-020-68040-z
Autor:
Dustin L. Updike, Michael Senter-Zapata, Paige C. Tanner, Anne C. Campbell, Ashley L. Kelly, Markus Terrey, Eraj Shafiq Khokhar, Karolina M. Andralojc, Ian M. Gans
Publikováno v:
PLoS Genetics
Plos Genetics, 13, 1-20
Plos Genetics, 13, 2, pp. 1-20
PLoS Genetics, Vol 13, Iss 2, p e1006611 (2017)
Plos Genetics, 13, 1-20
Plos Genetics, 13, 2, pp. 1-20
PLoS Genetics, Vol 13, Iss 2, p e1006611 (2017)
Germ cells contain non-membrane bound cytoplasmic organelles that help maintain germline integrity. In C. elegans they are called P granules; without them, the germline undergoes partial masculinization and aberrant differentiation. One key P-granule
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::722e79a1d446bb52bb9c352af7181163
https://doi.org/10.1371/journal.pgen.1006611
https://doi.org/10.1371/journal.pgen.1006611