Zobrazeno 1 - 10
of 124
pro vyhledávání: '"Ian M Carr"'
Publikováno v:
Bioinformatics and Biology Insights, Vol 18 (2024)
Gene ontology phrases are a widely used set of hierarchical terms that describe the biological properties of genes. These terms are then used to annotate individual genes, making it possible to determine the likely physiological properties of groups
Externí odkaz:
https://doaj.org/article/bf82eb50506349bab87c2f83b0ee78cb
Autor:
Belinda Baquero-Perez, Agne Antanaviciute, Ivaylo D Yonchev, Ian M Carr, Stuart A Wilson, Adrian Whitehouse
Publikováno v:
eLife, Vol 8 (2019)
N6-methyladenosine (m6A) is the most abundant internal RNA modification of cellular mRNAs. m6A is recognised by YTH domain-containing proteins, which selectively bind to m6A-decorated RNAs regulating their turnover and translation. Using an m6A-modif
Externí odkaz:
https://doaj.org/article/8f45fcf9731d40a1852c8fa1a6403483
Publikováno v:
PLoS ONE, Vol 13, Iss 2, p e0192170 (2018)
Epigenetic marks such as DNA methylation and histone modification can vary among plant accessions creating epi-alleles with different levels of expression competence. Mutations in epigenetic pathway functions are powerful tools to induce epigenetic v
Externí odkaz:
https://doaj.org/article/42460f72fff84912b010417dc4ba1402
Autor:
Christine P Diggle, Isabel Martinez-Garay, Zoltan Molnar, Martin H Brinkworth, Ed White, Ewan Fowler, Ruth Hughes, Bruce E Hayward, Ian M Carr, Christopher M Watson, Laura Crinnion, Aruna Asipu, Ben Woodman, P Louise Coletta, Alexander F Markham, T Neil Dear, David T Bonthron, Michelle Peckham, Ewan E Morrison, Eamonn Sheridan
Publikováno v:
PLoS ONE, Vol 12, Iss 4, p e0174264 (2017)
Tubulin alpha 8 (Tuba8) is the most divergent member of the highly conserved alpha tubulin family, and uniquely lacks two key post-translational modification sites. It is abundantly expressed in testis and muscle, with lower levels in the brain. We p
Externí odkaz:
https://doaj.org/article/018e0d0b0c5f4a439d4efb23ef2dfb63
Autor:
Kobey Karamendin, Aidyn Kydyrmanov, Yermukhammet Kasymbekov, Saule Asanova, Klara Daulbayeva, Aigerim Seidalina, Elizaveta Khan, Sally M Harrison, Ian M Carr, Simon J Goodman, Alibek Moldakozhayev, Marat Sayatov
Publikováno v:
PLoS ONE, Vol 12, Iss 12, p e0190339 (2017)
Three isolates APMV/gull/Kazakhstan/5976/2014, APMV/gull/Kazakhstan/ 5977/2014 and APMV/gull/Kazakhstan/5979/2014, were obtained from independent samples during annual surveillance for avian influenza and paramyxoviruses in wild birds from the Caspia
Externí odkaz:
https://doaj.org/article/d074f5ce41b343899d787e923eba718f
Autor:
Christopher M Watson, Laura A Crinnion, Sally M Harrison, Carolina Lascelles, Agne Antanaviciute, Ian M Carr, David T Bonthron, Eamonn Sheridan
Publikováno v:
PLoS ONE, Vol 11, Iss 6, p e0157075 (2016)
Next generation sequencing methodologies are facilitating the rapid characterisation of novel structural variants at nucleotide resolution. These approaches are particularly applicable to variants initially identified using alternative molecular meth
Externí odkaz:
https://doaj.org/article/824d612fa70a4520b39526d2fa623574
Autor:
Christine P Diggle, Daniel J Moore, Girish Mali, Petra zur Lage, Aouatef Ait-Lounis, Miriam Schmidts, Amelia Shoemark, Amaya Garcia Munoz, Mihail R Halachev, Philippe Gautier, Patricia L Yeyati, David T Bonthron, Ian M Carr, Bruce Hayward, Alexander F Markham, Jilly E Hope, Alex von Kriegsheim, Hannah M Mitchison, Ian J Jackson, Bénédicte Durand, Walter Reith, Eamonn Sheridan, Andrew P Jarman, Pleasantine Mill
Publikováno v:
PLoS Genetics, Vol 10, Iss 9, p e1004577 (2014)
Cilia are highly conserved microtubule-based structures that perform a variety of sensory and motility functions during development and adult homeostasis. In humans, defects specifically affecting motile cilia lead to chronic airway infections, infer
Externí odkaz:
https://doaj.org/article/221a47d3cc01479e8e83de40453586ea
Autor:
Christopher M Watson, Mohammed El-Asrag, David A Parry, Joanne E Morgan, Clare V Logan, Ian M Carr, Eamonn Sheridan, Ruth Charlton, Colin A Johnson, Graham Taylor, Carmel Toomes, Martin McKibbin, Chris F Inglehearn, Manir Ali
Publikováno v:
PLoS ONE, Vol 9, Iss 8, p e104281 (2014)
Retinal dystrophies are genetically heterogeneous, resulting from mutations in over 200 genes. Prior to the development of massively parallel sequencing, comprehensive genetic screening was unobtainable for most patients. Identifying the causative ge
Externí odkaz:
https://doaj.org/article/90cf5e0403ae4c868eed24f25f38499b
Autor:
Ian M Carr, Christine P Diggle, Kamron Khan, Chris Inglehearn, Martin McKibbin, David T Bonthron, Alexander F Markham, Rashida Anwar, Angus Dobbie, Sergio D J Pena, Manir Ali
Publikováno v:
PLoS ONE, Vol 7, Iss 8, p e43466 (2012)
Whilst the majority of inherited diseases have been found to be caused by single base substitutions, small insertions or deletions (
Externí odkaz:
https://doaj.org/article/d168e93b68dd4b10b977255d9e742357
Autor:
Aidyn Kydyrmanov, Kobey Karamendin, Yermukhammet Kassymbekov, Marat Kumar, Shynar Mazkirat, Symbat Suleimenova, Mirgaliy Baimukanov, Ian M. Carr, Simon J. Goodman
Publikováno v:
Frontiers in Marine Science. 10
Disease surveillance of marine mammal populations is essential to understand the causes of strandings, identify potential threats to animal health, and to support development of conservation strategies. Here we report the first large multi-pathogen s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ed28751caeb37af62f95487cdafe3b1c