Zobrazeno 1 - 10
of 402
pro vyhledávání: '"Ian M Anderson"'
Autor:
Zsuliet Kristof, Nora Eszlari, Sara Sutori, Zsofia Gal, Dora Torok, Daniel Baksa, Peter Petschner, Beata Sperlagh, Ian M Anderson, John Francis William Deakin, Gabriella Juhasz, Gyorgy Bagdy, Xenia Gonda
Publikováno v:
PLoS ONE, Vol 16, Iss 6, p e0252766 (2021)
The P2X purinoceptor 7 (P2RX7) mediates inflammatory microglial responses and is implicated in neuroimmune mechanisms of depression and neurodegenerative disorders. A number of studies suggest that psychosocial stress may precipitate depression throu
Externí odkaz:
https://doaj.org/article/6a53842c27204f458916cea46a0bd37e
Autor:
Ian M Anderson, Andrew Blamire, Tim Branton, Sabrina Brigadoi, Ross Clark, Darragh Downey, Graham Dunn, Andrew Easton, Rebecca Elliott, Clare Elwell, Katherine Hayden, Fiona Holland, Salman Karim, Jo Lowe, Colleen Loo, Rajesh Nair, Timothy Oakley, Antony Prakash, Parveen K Sharma, Stephen R Williams, R Hamish McAllister-Williams
Publikováno v:
Efficacy and Mechanism Evaluation, Vol 4, Iss 2 (2017)
Background: Electroconvulsive therapy (ECT) is the most effective acute treatment for severe depression, but there are concerns about its adverse cognitive effects. ECT may impair cognition through stimulation of glutamate receptors, and preliminary
Externí odkaz:
https://doaj.org/article/e8f7610ed14c41008f3217830aa334ab
Autor:
I Nicol Ferrier, Ian M Anderson, Jane Barnes, Peter Gallagher, Heinz CR Grunze, Peter M Haddad, Allan O House, Tom Hughes, Adrian J Lloyd, Chrysovalanto Mamasoula, Elaine McColl, Simon Pearce, Najma Siddiqi, Baxi Sinha, Chris Speed, Nick Steen, June Wainwright, Stuart Watson, Fiona H Winter, R Hamish McAllister-Williams, the ADD Study Team
Publikováno v:
Efficacy and Mechanism Evaluation, Vol 2, Iss 4 (2015)
Background: Depressed patients who do not respond to second-line antidepressant drugs are characterised as suffering from treatment-refractory depression (TRD). Chronic psychosocial stress hypothalamic–pituitary–adrenal (HPA) axis dysfunction is
Externí odkaz:
https://doaj.org/article/3d74dfb8adfd4995a7284d41960e5c5a
Autor:
Zsuliet Kristof, Zsofia Gal, Dora Torok, Nora Eszlari, Sara Sutori, Berta Erdelyi-Hamza, Peter Petschner, Beata Sperlagh, Ian M. Anderson, John Francis William Deakin, Gyorgy Bagdy, Gabriella Juhasz, Xenia Gonda
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-13 (2023)
Abstract Emotional stress is a leading risk factor in the development of neuropsychiatric disorders possibly via immune activation. P2X7 receptors promote neuroinflammation, and research suggests a relationship between chromosome region 12q2431, in w
Externí odkaz:
https://doaj.org/article/81986f79dbbe4dbd83f4ed8d9fedeb10
Autor:
Cynthia H. Y. Fu, Guray Erus, Yong Fan, Mathilde Antoniades, Danilo Arnone, Stephen R. Arnott, Taolin Chen, Ki Sueng Choi, Cherise Chin Fatt, Benicio N. Frey, Vibe G. Frokjaer, Melanie Ganz, Jose Garcia, Beata R. Godlewska, Stefanie Hassel, Keith Ho, Andrew M. McIntosh, Kun Qin, Susan Rotzinger, Matthew D. Sacchet, Jonathan Savitz, Haochang Shou, Ashish Singh, Aleks Stolicyn, Irina Strigo, Stephen C. Strother, Duygu Tosun, Teresa A. Victor, Dongtao Wei, Toby Wise, Rachel D. Woodham, Roland Zahn, Ian M. Anderson, J. F. William Deakin, Boadie W. Dunlop, Rebecca Elliott, Qiyong Gong, Ian H. Gotlib, Catherine J. Harmer, Sidney H. Kennedy, Gitte M. Knudsen, Helen S. Mayberg, Martin P. Paulus, Jiang Qiu, Madhukar H. Trivedi, Heather C. Whalley, Chao-Gan Yan, Allan H. Young, Christos Davatzikos
Publikováno v:
BMC Psychiatry, Vol 23, Iss 1, Pp 1-18 (2023)
Abstract Background Efforts to develop neuroimaging-based biomarkers in major depressive disorder (MDD), at the individual level, have been limited to date. As diagnostic criteria are currently symptom-based, MDD is conceptualized as a disorder rathe
Externí odkaz:
https://doaj.org/article/c4130b307f0648e6a85a0f1b24a7458d
Autor:
Zsuliet Kristof, Zsofia Gal, Dora Torok, Nora Eszlari, Sara Sutori, Beata Sperlagh, Ian M. Anderson, Bill Deakin, Gyorgy Bagdy, Gabriella Juhasz, Xenia Gonda
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 2, p 865 (2024)
Both early childhood traumatic experiences and current stress increase the risk of suicidal behaviour, in which immune activation might play a role. Previous research suggests an association between mood disorders and P2RX7 gene encoding P2X7 recepto
Externí odkaz:
https://doaj.org/article/b49298f8d48e44f18b0191fa7fde87de
Autor:
Alish B. Palmos, Stuart Watson, Tom Hughes, Andreas Finkelmeyer, R. Hamish McAllister-Williams, Nicol Ferrier, Ian M. Anderson, Rajesh Nair, Allan H. Young, Rebecca Strawbridge, Anthony J. Cleare, Raymond Chung, Souci Frissa, Laura Goodwin, Matthew Hotopf, Stephani L. Hatch, Hong Wang, David A. Collier, Sandrine Thuret, Gerome Breen, Timothy R. Powell
Publikováno v:
BJPsych Open, Vol 5 (2019)
BackgroundChildhood maltreatment is one of the strongest predictors of adulthood depression and alterations to circulating levels of inflammatory markers is one putative mechanism mediating risk or resilience.AimsTo determine the effects of childhood
Externí odkaz:
https://doaj.org/article/ba32019057c1460bbee994a5c0feedf1
Autor:
Felipe Guapo, Tomos E. Morgan, Florian Füssl, Ian M. Anderson, Daniel Forsey, Jonathan Bones, Lisa Strasser
Publikováno v:
Analytical Chemistry
Adeno-associated virus (AAV)-based gene therapy is a rapidly developing field, requiring analytical methods for detailed product characterization. One important quality attribute of AAV products that requires monitoring is the amount of residual empt
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0ea3010fba507ee3ee98bc42bcc506d5
https://doi.org/10.1021/acs.analchem.1c02828
https://doi.org/10.1021/acs.analchem.1c02828
Autor:
Ian M. Anderson
Publikováno v:
BJPsych Advances. 27:285-291
SUMMARYElectroconvulsive therapy (ECT) for depression is a controversial treatment with highly polarised views about the balance between therapeutic benefits and adverse effects. Studies investigating whether ECT is more effective than a placebo trea
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::133a27a311a6cd83438b9f829979e9a8
https://doi.org/10.1192/bja.2021.23
https://doi.org/10.1192/bja.2021.23
Autor:
Ian M. Anderson
Publikováno v:
BJPsych Advances. :1-2
SUMMARY Benzodiazepines have attracted controversy from shortly after their introduction. They have been subject to periodic calls for their use to be re-evaluated on the basis that their risks have been overstated and their benefits underappreciated
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::90c07100cfa00672b2c1e40b1286ddcb
https://doi.org/10.1192/bja.2022.85
https://doi.org/10.1192/bja.2022.85