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pro vyhledávání: '"Ian K. Gurrell"'
Autor:
M. Catarina Silva, Ghata A. Nandi, Sharon Tentarelli, Ian K. Gurrell, Tanguy Jamier, Diane Lucente, Bradford C. Dickerson, Dean G. Brown, Nicholas J. Brandon, Stephen J. Haggarty
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-18 (2020)
Disruption of autophagy function in cellular and animal models of tauopathy increases tau aggregation. Here, the authors describe a small-molecule screen to identify compounds that promote autophagy clearance of tau and rescue disease-relevant phenot
Externí odkaz:
https://doaj.org/article/8c984694d54f4d749b8a1bed03dbaffc