Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Ian K Wright"'
Autor:
Sung-Eun Bae, Ian K Wright, Cathy Wyse, Nathalie Samson-Desvignes, Pascale Le Blanc, Serge Laroche, David G Hazlerigg, Jonathan D Johnston
Publikováno v:
PLoS ONE, Vol 9, Iss 3, p e90056 (2014)
Melatonin receptor expression exhibits profound developmental changes through poorly understood mechanisms. In mammals, a current model suggests that pubertal reactivation of gonadotrophin-releasing hormone (GnRH) secretion down-regulates MT1 melaton
Externí odkaz:
https://doaj.org/article/c30203ecf91947d0b4dcbdb9dafa1e4d
Autor:
Ian K. Wright, Gregor Broessner, Uwe Reuter, Robert A. Lenz, Daniel D. Mikol, Yngve Hallström, Feng Zhang, Jo H. Bonner, Hernan Picard, Jan Klatt, Peter J. Goadsby, Denise E. Chou
Publikováno v:
Neurology
article-version (Version of Record) 3
article-version (Version of Record) 3
ObjectiveTo assess efficacy and tolerability of 1-year erenumab treatment in patients with episodic migraine.MethodsPatients were randomized (n = 955; 1:1:1) during the 24-week double-blind treatment phase (DBTP) to monthly subcutaneous placebo or er
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::848d8fc94b80c248668e5065db0a6199
https://doi.org/10.1212/wnl.0000000000010019
https://doi.org/10.1212/wnl.0000000000010019
Publikováno v:
ACS Applied Materials & Interfaces. 2:2360-2364
We demonstrate the operation of a device that can produce chitosan nanoparticles in a tunable size range from 50-300 nm with small size dispersion. A piezoelectric oscillator operated at megahertz frequencies is used to aerosolize a solution containi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::567a91a0865bde75298fee037bbcb185
https://doi.org/10.1021/am100375w
https://doi.org/10.1021/am100375w
Publikováno v:
European Journal of Pharmacology. 239:195-202
The neurochemical profile of the selective 5-HT1A receptor antagonist WAY100135 [N-tert-butyl 3-4-(2-methoxyphenyl) piperazin-1-yl-2-phenylpropanamide dihydrochloride] and its enantiomers at the somatodendritic 5-HT1A receptor was determined by study
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::612969a0c83bde257c7e8ecfd489d99f
https://doi.org/10.1016/0014-2999(93)90994-s
https://doi.org/10.1016/0014-2999(93)90994-s
Autor:
Helen Crooke, Felicity J. Haines, S. Anna La Rocca, Helen L. Johns, Trevor W. Drew, Helen Everett, Ian K. Wright, Simon P. Graham, Meenakshi Khatri
Publikováno v:
Veterinary microbiology. 142(1-2)
Existing live attenuated classical swine fever virus (CSFV) vaccines provide a rapid onset of complete protection but pose problems in discriminating infected amongst vaccinated animals. With a view to providing additional information on the cellular
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5e0a639248ebe63631706f5c6c734803
https://pubmed.ncbi.nlm.nih.gov/19854006
https://pubmed.ncbi.nlm.nih.gov/19854006
Publikováno v:
Physiology & Behavior. 50:1129-1132
Rats were reared from weaning either in isolation or in social groups for 30 days and their behaviour on the elevated X-maze was studied. Isolation-reared rats displayed an anxiogenic profile on the X-maze compared to socially reared controls. Resoci
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::983dd4666786b804bb9c401f7d5db1a6
https://doi.org/10.1016/0031-9384(91)90572-6
https://doi.org/10.1016/0031-9384(91)90572-6
Publikováno v:
Psychopharmacology. 105:259-263
Rats were reared from weaning (21 days of age) either in isolation or in social groups of five for 30 days and were then tested for spontaneous locomotor activity and 7 days later for 5-hydroxytryptamine (5-HT) agonist-induced behaviour. Isolation-re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8dfd6a7129b1de93e5e11738f6b201b1
https://doi.org/10.1007/bf02244319
https://doi.org/10.1007/bf02244319
Publikováno v:
Naunyn-Schmiedeberg's archives of pharmacology. 352(2)
The aim of this study was to use a 3H-adenine pre-labelling technique to characterise the effect of α2-adrenoceptor activation on forskolin-stimulated cyclic AMP accumulation in the isolated porcine palmar lateral vein. Forskolin (10−7–10−4 M)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::47de392ccc7a864d0061a76255b4eac8
https://pubmed.ncbi.nlm.nih.gov/7477432
https://pubmed.ncbi.nlm.nih.gov/7477432
Publikováno v:
British journal of pharmacology. 114(3)
1. The aim of this study was to investigate constrictor alpha-adrenoceptors in three isolated blood vessels of the pig, the thoracic aorta (TA), the splenic artery (SA) and marginal ear vein (MEV) and then compare the functional response with the den
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::040ba094609ca31c8ee06e7c95e97adb
https://pubmed.ncbi.nlm.nih.gov/7735695
https://pubmed.ncbi.nlm.nih.gov/7735695
1. We have examined the effect of elevation of cellular adenosine 3':5'-cyclic monophosphate (cyclic AMP) on alpha 1- and alpha 2-adrenoceptor-mediated contraction of the isolated palmar lateral vein of the pig. Cellular cyclic AMP was increased by e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ab80c6f58e236e865d8074e8f2ed2176
https://europepmc.org/articles/PMC1510157/
https://europepmc.org/articles/PMC1510157/
