Zobrazeno 1 - 10
of 447
pro vyhledávání: '"Ian Judson"'
Autor:
Jessica Burns, Christopher P. Wilding, Lukas Krasny, Xixuan Zhu, Madhumeeta Chadha, Yuen Bun Tam, Hari PS, Aswanth H. Mahalingam, Alexander T. J. Lee, Amani Arthur, Nafia Guljar, Emma Perkins, Valeriya Pankova, Andrew Jenks, Vanessa Djabatey, Cornelia Szecsei, Frank McCarthy, Chanthirika Ragulan, Martina Milighetti, Theodoros I. Roumeliotis, Stephen Crosier, Martina Finetti, Jyoti S. Choudhary, Ian Judson, Cyril Fisher, Eugene F. Schuster, Anguraj Sadanandam, Tom W. Chen, Daniel Williamson, Khin Thway, Robin L. Jones, Maggie C. U. Cheang, Paul H. Huang
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-17 (2023)
Abstract Soft tissue sarcomas (STS) are rare and diverse mesenchymal cancers with limited treatment options. Here we undertake comprehensive proteomic profiling of tumour specimens from 321 STS patients representing 11 histological subtypes. Within l
Externí odkaz:
https://doaj.org/article/9d213184d1a64b60a226a35cf5a6990a
Autor:
Georgios Kantidakis, Saskia Litière, Hans Gelderblom, Marta Fiocco, Ian Judson, Winette T.A. van der Graaf, Antoine Italiano, Sandrine Marréaud, Stefan Sleijfer, Gunhild Mechtersheimer, Christina Messiou, Bernd Kasper
Publikováno v:
Sarcoma, Vol 2022 (2022)
Background. Soft-tissue sarcomas (STS) constitute a rare group of heterogeneous mesenchymal tumours containing more than 100 histologic subtypes. Here, we investigate whether, and if so, to what extent, skeletal metastases affect the outcome of patie
Externí odkaz:
https://doaj.org/article/25ec7fab08104814b3d6fdf06f2f5c0a
Autor:
Axel Le Cesne, Sebastian Bauer, George D. Demetri, Guangyang Han, Luca Dezzani, Qasim Ahmad, Jean-Yves Blay, Ian Judson, Patrick Schöffski, Massimo Aglietta, Peter Hohenberger, Hans Gelderblom
Publikováno v:
BMC Cancer, Vol 19, Iss 1, Pp 1-7 (2019)
Abstract Background PALETTE is a phase 3 trial that demonstrated single-agent activity of pazopanib in advanced soft tissue sarcomas (aSTS). We performed retrospective subgroup analyses to explore potential relationships between patient characteristi
Externí odkaz:
https://doaj.org/article/e7be3d15549546a4b191211c85af8d93
Autor:
Ian Judson, Christina Messiou
Publikováno v:
Gynecologic Oncology Reports, Vol 35, Iss , Pp 100681- (2021)
This is a case of recurrent intravascular leiomyomatosis in a pre-menopausal woman of African-Caribbean heritage. She presented in 2006 with multiple uterine leiomyomata, tumour invading the inferior vena cava (IVC) extending into the right atrium, a
Externí odkaz:
https://doaj.org/article/fc063ba1d3c041b7a04c21e5dc5bfac1
Publikováno v:
PLoS ONE, Vol 14, Iss 9, p e0210731 (2019)
OBJECTIVE:Soft tissue sarcoma (STS) is a rare cancer type that when locally advanced or metastatic, is predominantly treated with palliative chemotherapy with the aim of improving both quantity and quality of life. Given modest survival data after co
Externí odkaz:
https://doaj.org/article/fd69f48122db49bda2e580da1d53a3b7
Autor:
Joanna Vitfell-Rasmussen, Ian Judson, Akmal Safwat, Robin L. Jones, Philip Blach Rossen, Maja Lind-Hansen, Poul Knoblauch, Anders Krarup-Hansen
Publikováno v:
Sarcoma, Vol 2016 (2016)
Background. Belinostat is a novel histone deacetylase inhibitor. Primary Objectives. Maximum tolerated dose (MTD) and dose limiting toxicities (DLTs) of belinostat (Bel) in combination with doxorubicin (Dox) in solid tumours (phase I) and response ra
Externí odkaz:
https://doaj.org/article/bf901b03196d47cd83c4ec0cdd396221
Autor:
Ian Judson, Michael Leahy, Jeremy Whelan, Paul Lorigan, Mark Verrill, Robert Grimer, Martin Robinson
Publikováno v:
Sarcoma, Vol 6, Iss 3, Pp 83-87 (2002)
Gastrointestinal stromal tumour (GIST) is the commonest mesenchymal tumour to affect the gastrointestinal tract. Appropriate management requires accurate diagnosis and the skills of a multidisciplinary team. Surgery is the only curative treatment opt
Externí odkaz:
https://doaj.org/article/b60ba0310acd43fb9f5e0903227fe725
Publikováno v:
Case Reports in Medicine, Vol 2014 (2014)
Clear cell sarcoma-like tumor of the gastrointestinal tract (CCSLGT) is a rare malignant neoplasm arising within the wall of the small bowel, stomach, or large bowel, predominantly in children and young adults. It is an aggressive tumor with a high r
Externí odkaz:
https://doaj.org/article/a64af970243549a9b0e6333f55297895
Clinical Activity and Tolerability of a 14-Day Infusional Ifosfamide Schedule in Soft-Tissue Sarcoma
Autor:
Juan Martin-Liberal, Salma Alam, Anastasia Constantinidou, Cyril Fisher, Komel Khabra, Christina Messiou, David Olmos, Scott Mitchell, Omar Al-Muderis, Aisha Miah, Mark Linch, Robin L. Jones, Michelle Scurr, Ian Judson, Charlotte Benson
Publikováno v:
Sarcoma, Vol 2013 (2013)
Externí odkaz:
https://doaj.org/article/57b74992795a42c8af2387313ccb73b0
Publikováno v:
Sarcoma, Vol 2011 (2011)
Introduction. The symptom burden and role of palliative care (PC) in patients with advanced soft tissue sarcoma (STS) are not well defined. Methods. This study retrospectively reviewed both symptoms and PC involvement in patients known to an STS refe
Externí odkaz:
https://doaj.org/article/1d4378b395704bf181587197d3dab4ed